Tupaia chinensis (Chinese tree shrew): 102491327 Help Entry 102491327         CDS       T02978                                  Name (RefSeq) steroid 21-hydroxylase   KO K00513   steroid 21-monooxygenase [EC:1.14.14.16] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00140   Steroid hormone biosynthesis tup01100   Metabolic pathways tup04925   Aldosterone synthesis and secretion tup04927   Cortisol synthesis and secretion tup04934   Cushing syndrome Module tup_M00109   C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     102491327  09150 Organismal Systems   09152 Endocrine system    04925 Aldosterone synthesis and secretion     102491327    04927 Cortisol synthesis and secretion     102491327  09160 Human Diseases   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102491327  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:tup00199]     102491327 Enzymes [BR:tup01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.16  steroid 21-monooxygenase      102491327 Cytochrome P450 [BR:tup00199]  Cytochrome P450, animal type   CYP21 family    102491327 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  102491327 NCBI-ProteinID:  XP_006154384 LinkDB All DBs Position Un AA seq 531 aa AA seqDB search MDGQRFEVQTCQGQWDRCHAENVPLCGRDNRKRPEGRGQERPQNSPAGSVAGLESYKWPS RGLCQVSAMLFFGLLLLALLAGAQLLRGWWGPRSLHLPPLAPGFLHLLQPNLPIHLLGLT QTLGPVYRLRLRRPDVVVLNSKKTIEEAMVRKWVDFAGRPHLWSYKLVSEHHPDLSLGDY SLLWKAHKRLTRSALALGMGSSMEPLVEQMTQEFCERMRAQAGAPVAIQKEFSFLTCSII CYLTFGDKVKAALTAPRLCVQDVMKAWAHWSIQILDMVPFLRFVPNPVLRRLRQVVENRD HIVERQLRQHKESLVAGQWRDMTDYMLQGVGQHRAEGPRQLHEGHVHMAVVDLFIGGTET TATTLSWAVAFLLHHPEIQQQLQEELDLALGPCTSGSRVVYADRTRLPLLNATIAEVLRL RPVVPLALPHHTTRRSSVCGYDIPKGTVIIPNLQGAHLDATVWDQPHEFRPDRFLEPGKS PRAAFTLLPPPAGTLPSLQPQPYGGVNLTMQPFQVCLQPRGGEAPGLGQCQ NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt atggatgggcagcgttttgaagtgcagacttgccaaggtcaatgggaccgctgccatgct gagaatgtccccctttgtgggcgggacaacaggaagagacctgaaggtaggggccaggag aggccccaaaacagtccggcaggatcggtggcagggctcgagagctataagtggccgtcc cggggcctttgccaggtttctgccatgctgttcttcgggttgctgctgctggccctgctg gctggtgcccagctgctgaggggctggtgggggccccggagcctccacctgccccctctc gccccgggcttcctgcacctgctgcagcccaacctccccatccacctgctcggcctgaca cagacgctcgggcctgtctacaggctgcggctccggcggcccgacgtggtggtgctgaac tccaagaagaccatcgaagaggccatggtcaggaagtgggtggactttgccggcaggccc cacttatggtcctacaagctggtgtctgagcaccacccagacctgtccctaggggactac tccctgctctggaaggcccacaagaggctcacccgctccgccctggcgctgggcatgggc agctccatggagcccttggtggagcagatgacccaggagttctgcgagcgcatgagggcc caggccggcgcccccgtggccatccagaaggagttctccttcctcacctgcagcatcatc tgctacctcacgttcggagacaaggtcaaggctgccctcacagcccctcggctctgcgtc caggacgtgatgaaagcctgggcccactggtccatccagattctggacatggttcccttt cttaggttcgtgcccaacccggtgctccggaggctgaggcaggtcgtggagaacagggac cacattgtggagaggcagctgagacagcacaaggagagcctggtggccggccagtggagg gacatgacggactacatgctccaaggggtggggcagcacagagcggagggcccccggcag ctccacgagggccacgtgcacatggctgtggtggacctcttcatcgggggcaccgagacc acagcgaccacactgtcctgggccgtggctttcctgcttcaccaccctgagatccagcag caactgcaggaggagttagacctggccctgggcccctgcacctccggctcccgggtggtg tacgcggaccgcacgcggctgcccctgctcaacgccaccatcgccgaggtgctgcggctg cggcccgtcgtgcccttggccttgccccaccacaccacgcggcgcagcagcgtctgtggc tatgacatccccaagggcaccgtcatcatccccaacctccaaggcgcccacctggacgcg acggtctgggatcagccccacgagttccggcctgatcgcttcctggagcctggcaagagc ccccgagcggccttcacgctgctgccgccgcccgccggcaccctgccctccctgcagccc cagccctacggcggcgtcaacctcaccatgcagcctttccaggtgtgcctgcaaccccgg ggcggggaggccccgggcctgggccagtgccagtga

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