Ursus arctos (brown bear): 113262259 Help Entry 113262259         CDS       T05909                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X3   KO K02187   caspase 3 [EC:3.4.22.56] Organism uah  Ursus arctos (brown bear) Pathway uah01524   Platinum drug resistance uah04010   MAPK signaling pathway uah04115   p53 signaling pathway uah04148   Efferocytosis uah04210   Apoptosis uah04215   Apoptosis - multiple species uah04623   Cytosolic DNA-sensing pathway uah04650   Natural killer cell mediated cytotoxicity uah04657   IL-17 signaling pathway uah04668   TNF signaling pathway uah04726   Serotonergic synapse uah04932   Non-alcoholic fatty liver disease uah04933   AGE-RAGE signaling pathway in diabetic complications uah04936   Alcoholic liver disease uah05010   Alzheimer disease uah05012   Parkinson disease uah05014   Amyotrophic lateral sclerosis uah05016   Huntington disease uah05020   Prion disease uah05022   Pathways of neurodegeneration - multiple diseases uah05132   Salmonella infection uah05133   Pertussis uah05134   Legionellosis uah05145   Toxoplasmosis uah05146   Amoebiasis uah05152   Tuberculosis uah05160   Hepatitis C uah05161   Hepatitis B uah05162   Measles uah05163   Human cytomegalovirus infection uah05164   Influenza A uah05165   Human papillomavirus infection uah05167   Kaposi sarcoma-associated herpesvirus infection uah05168   Herpes simplex virus 1 infection uah05169   Epstein-Barr virus infection uah05170   Human immunodeficiency virus 1 infection uah05200   Pathways in cancer uah05203   Viral carcinogenesis uah05205   Proteoglycans in cancer uah05206   MicroRNAs in cancer uah05210   Colorectal cancer uah05222   Small cell lung cancer uah05416   Viral myocarditis uah05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     113262259 (CASP3)    04668 TNF signaling pathway     113262259 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     113262259 (CASP3)   09143 Cell growth and death    04210 Apoptosis     113262259 (CASP3)    04215 Apoptosis - multiple species     113262259 (CASP3)    04115 p53 signaling pathway     113262259 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     113262259 (CASP3)    04650 Natural killer cell mediated cytotoxicity     113262259 (CASP3)    04657 IL-17 signaling pathway     113262259 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     113262259 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     113262259 (CASP3)    05206 MicroRNAs in cancer     113262259 (CASP3)    05205 Proteoglycans in cancer     113262259 (CASP3)    05203 Viral carcinogenesis     113262259 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     113262259 (CASP3)    05222 Small cell lung cancer     113262259 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     113262259 (CASP3)    05161 Hepatitis B     113262259 (CASP3)    05160 Hepatitis C     113262259 (CASP3)    05164 Influenza A     113262259 (CASP3)    05162 Measles     113262259 (CASP3)    05168 Herpes simplex virus 1 infection     113262259 (CASP3)    05163 Human cytomegalovirus infection     113262259 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     113262259 (CASP3)    05169 Epstein-Barr virus infection     113262259 (CASP3)    05165 Human papillomavirus infection     113262259 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     113262259 (CASP3)    05133 Pertussis     113262259 (CASP3)    05134 Legionellosis     113262259 (CASP3)    05152 Tuberculosis     113262259 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     113262259 (CASP3)    05145 Toxoplasmosis     113262259 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     113262259 (CASP3)    05012 Parkinson disease     113262259 (CASP3)    05014 Amyotrophic lateral sclerosis     113262259 (CASP3)    05016 Huntington disease     113262259 (CASP3)    05020 Prion disease     113262259 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     113262259 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     113262259 (CASP3)    05416 Viral myocarditis     113262259 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     113262259 (CASP3)    04932 Non-alcoholic fatty liver disease     113262259 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     113262259 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     113262259 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uah01002]     113262259 (CASP3) Enzymes [BR:uah01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      113262259 (CASP3) Peptidases and inhibitors [BR:uah01002]  Cysteine peptidases   Family C14: caspase family    113262259 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  113262259 NCBI-ProteinID:  XP_026364368 LinkDB All DBs Position Unknown AA seq 277 aa AA seqDB search MENTEHTVDAKAIKNSETKILHGSKSVDSGMSLDNSYKMDYPEMGLCIIINNKNFHRSTG MTARSGTDVDAANLRETFTNLKYEVRNKNDLTREEILELMDSVSKEDHSKRSSFVCVLLS HGDEGIIFGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGAED DMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCTMLKLYAHKLEFMHILTRVN RKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYLYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacaccgaacacacagtggatgcaaaagccattaaaaattcagaaacaaagatc ttacatgggagcaaatcagtggactctggaatgtccttggacaacagttataaaatggat tatcctgaaatgggtttatgtataataattaataataagaactttcatagaagtactgga atgaccgctcggtctggtacagatgtagatgcagcaaacctccgggaaacattcacgaac ttgaagtatgaagtcaggaataaaaatgatctcacacgcgaagaaattttggaattaatg gacagtgtctctaaagaagatcatagcaaaaggagcagttttgtttgtgtgcttctaagc catggggatgaaggaataatttttggaacaaatggacctgttgacctgaaaaaattaaca ggtttcttcagaggggattactgtcgaagtctgactggaaaacccaaacttttcattatt caggcctgccgaggcacagaactggactgcggtattgagacggacagcggagcagaggac gacatggcctgtcagaaaataccagttgaagcggacttcttgtatgcctattctacagcc cctggttactactcatggcgaaattcgaaggacggatcctggttcatccagtcactttgt acgatgctgaaactgtatgctcacaagcttgagtttatgcacattcttacccgggttaac cggaaggtagccacagaatttgagtccttctctcttgactctgcttttcatggaaagaaa cagattccgtgtattgtgtcgatgctcacaaaagaactgtatctttatcactaa

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