Ursus americanus (American black bear): 123775491
Help
Entry
123775491 CDS
T07931
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00350
Tyrosine metabolism
uar00790
Folate biosynthesis
uar01100
Metabolic pathways
uar04728
Dopaminergic synapse
uar04917
Prolactin signaling pathway
uar05012
Parkinson disease
uar05030
Cocaine addiction
uar05031
Amphetamine addiction
uar05034
Alcoholism
Module
uar_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
123775491 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
123775491 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
123775491 (TH)
09156 Nervous system
04728 Dopaminergic synapse
123775491 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
123775491 (TH)
09165 Substance dependence
05030 Cocaine addiction
123775491 (TH)
05031 Amphetamine addiction
123775491 (TH)
05034 Alcoholism
123775491 (TH)
Enzymes [BR:
uar01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
123775491 (TH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
123775491
NCBI-ProteinID:
XP_045626678
LinkDB
All DBs
Position
Unknown
AA seq
524 aa
AA seq
DB search
MPTPSTASPQAKGFRRAVSELDAKQAEAIMVRGLPGPGGQNGSWPGWGRPSTGCVLSPQS
PRFIGRRQSLIEDARKEREKAEAASAAASEPGDPLEAAVVKDKDGKATLNLLFTLRGTKT
APLSRAVKAFETFEAQIHHLETRPAQRPRAGGPHLEYFVRCEVPSADLPALLSSVRRVAE
DVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQY
KHGDPIPRVEYTAEEIATWKEVYTTLKGLYITHACREYLEAFQLLERFSGYREDNIPQLE
DVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELL
GHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLL
SSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSVYFVSESFSDAKDKLRNYASRIQR
PFSVKFDPYTLAIDVLDSPHAIRRSLEGVQEELHTLAHALSAIS
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagcaccgcctccccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaggccatcatggtaagggggctgccggggcccggcggccag
aacgggtcctggccgggctgggggcggccgagcacagggtgtgtcctgtccccacagtcc
ccgcgcttcattgggcggcgacagagcctcatcgaggacgctcgcaaggagcgagagaag
gccgaggcagcgtcagccgctgcctcggagcccggagaccccctagaggccgccgtggtc
aaggacaaggacgggaaggccacgctgaaccttctcttcaccctacggggcaccaagacc
gcgccactgtcccgggccgtgaaggcgtttgaaacatttgaagcccaaatccaccacctg
gagacccggcctgcccagaggccacgggcaggcggcccccacctggagtactttgtgcgc
tgcgaggtgcccagcgccgacctgccggccctgctcagctccgtgcgccgggtggcggag
gacgtgcgtggcgccggggagaacaaggtcctctggttcccgaggaaagtttccgagctg
gacaagtgccaccatctggtcaccaagtttgaccctgacctggacttggatcacccgggc
ttctcggaccaggtgtaccgccagcgccggaagctgattgcggagatagcgttccagtac
aagcacggtgaccctattccccgcgtggagtacacggccgaggagatagccacctggaag
gaggtctacaccaccctcaagggcctctacatcacccacgcctgccgggagtacctggag
gccttccagctgctggagcgcttcagcgggtacagggaggacaacatcccgcagctggag
gacgtgtcccgcttcctgaaggagcggacaggcttccagctgcggcccgtggctggcctg
ctgtccgcccgggacttcctggccagcctggccttccgagtgttccagtgcacccagtac
atccggcacgcctcctcgcccatgcactcccctgagccggactgctgccatgagctgctg
gggcacgtgcccatgctggctgaccggacctttgctcagttctcccaggacatcgggctc
gcgtccttgggggcttctgacgaggaaattgagaagctgtccacgctatactggttcacg
gtggagttcgggctgtgtaagcagaacggcgaggtgaaggcctacggtgctgggctgctg
tcctcctacggggagctcctgcactccctgtctgaggaacccgagatccgggccttcgac
cccgatgctgcggccgtgcagccttaccaggaccagacctaccagtctgtctactttgtg
tccgaaagtttcagcgacgccaaggacaagctcaggaactacgcttcccgcatccagcgc
cccttctccgtgaagttcgacccgtatacactggccatcgacgtgctggacagtccccac
gcgatccggcgctccctggagggcgtccaggaggagctgcacacgctcgcacacgcgctg
agcgccatcagctag
DBGET
integrated database retrieval system
