Ursus americanus (American black bear): 123785006 Help Entry 123785006         CDS       T07931                                  Symbol F2 Name (RefSeq) prothrombin   KO K01313   coagulation factor II (thrombin) [EC:3.4.21.5] Organism uar  Ursus americanus (American black bear) Pathway uar04072   Phospholipase D signaling pathway uar04080   Neuroactive ligand-receptor interaction uar04610   Complement and coagulation cascades uar04611   Platelet activation uar04810   Regulation of actin cytoskeleton uar05171   Coronavirus disease - COVID-19 uar05200   Pathways in cancer Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     123785006 (F2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     123785006 (F2)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     123785006 (F2)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     123785006 (F2)    04611 Platelet activation     123785006 (F2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123785006 (F2)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     123785006 (F2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123785006 (F2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:uar04147]     123785006 (F2)    00536 Glycosaminoglycan binding proteins [BR:uar00536]     123785006 (F2) Enzymes [BR:uar01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.21  Serine endopeptidases     3.4.21.5  thrombin      123785006 (F2) Peptidases and inhibitors [BR:uar01002]  Serine peptidases   Family S1: chymotrypsin family    123785006 (F2) Exosome [BR:uar04147]  Exosomal proteins   Exosomal proteins of hepatic cells    123785006 (F2) Glycosaminoglycan binding proteins [BR:uar00536]  Heparan sulfate / Heparin   Coagulation and fibrinolysis    123785006 (F2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2 Motif Other DBs NCBI-GeneID:  123785006 NCBI-ProteinID:  XP_045642499 LinkDB All DBs Position Unknown AA seq 623 aa AA seqDB search MAHIRGLWVPGCLALAVLFSLVHSQHAVFLAPQQALSLLQRVRRANSGFLEELRKGNLER ECVEEKCSYEEAFEALESSIATDVFWTKYTACESVRKPREKLTECLEGSCAEGLGMNYRG NVSFTRSGIECQLWRSRYPHKPEINTTTHPGADLRENFCRNPDGSTTGPWCYTTDPTVRR EECSIPVCGGGGVTVQLTPRSRGPTVNLPPSSEHCVPERGRYYQGRQAVTAHGSTCLAWA SSQAKALSKDQDFNPAVPLVENFCRNPDGDEEGAWCYVSEGPGGFEYCDLDYCEEPVEEV GDGLAEDPDAAIEGRTGDEEFQPFFNEKTFGAGEADCGLRPLFEKSLVKDKTEHELLESY IDGRVVEGWDAEIGLAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE NDLLVRIGKHSRTRYERSIEKISMLEKIYIHPRYNWRENLDRDIALLRLKKPIAFSNYIH PVCLPDKDTAVRLLRAGYKGRVTGWGNLKEMWTSSVTEVQPSVLQVVNLPIVERPVCKAS TRIRITDNMFCAGFKPNEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK YGFYTHVFRLKKWIQKVIDQSGS NT seq 1872 nt NT seq  +upstreamnt  +downstreamnt atggcgcacatccgaggcctgtgggtacctggctgcctggccctagctgtcctgtttagc cttgtgcacagccagcatgcagtgttcctggcccctcagcaagcattatcgttgctccag cgggtccgacgcgccaacagtggcttcctggaggagttgcgcaaggggaacctggagcga gagtgtgtggaagagaagtgcagctacgaagaggcctttgaggccctggagtcttccatc gccacggatgtattctggaccaagtacacagcttgtgagtcggtgaggaaacctcgagaa aagctcactgaatgtctggaaggtagctgtgctgaaggtctgggtatgaattaccgaggg aacgtgagcttcacccggtcaggcatcgagtgtcagctctggaggagtcgctacccacat aagcctgaaatcaacactaccacccaccctggggcggacctgcgggagaatttctgccgt aacccggatggcagcaccactgggccctggtgctatacgacagaccccactgtgaggagg gaggagtgcagcatccctgtctgcggcggggggggcgtcactgtgcagctgaccccacgt tccagaggccccacggtgaatctgccaccttcatctgagcactgcgtccctgagcgtggc cggtactaccagggtcgccaggcagtgaccgcacatgggtccacctgcctggcctgggcc agcagtcaggctaaggcgctgagcaaggaccaggacttcaaccctgcggtgccgctggtg gagaatttctgccgcaaccccgacggggacgaggagggcgcgtggtgttatgtgtcggag gggcccggtggcttcgagtactgcgacctggactactgcgaggagcctgtggaagaggtg ggcgacgggctggccgaggacccagacgcggccatcgagggacgcaccggcgacgaggag ttccagcccttcttcaacgagaagactttcggcgccggggaggcagactgtgggctgcgg cctctgtttgagaagtcgttggtgaaggacaaaacggaacacgagcttctggagtcctac atcgacgggcgcgtcgtggagggttgggacgccgagattggcctcgcgccctggcaggtg atgcttttccggaagagtccccaggagctgctttgtggggccagcctcatcagtgaccgc tgggtccttactgctgcccactgtctcctgtacccaccttgggacaagaacttcaccgag aatgatcttctggtgcgcattggcaagcactcccgcaccaggtatgagcgaagcattgag aagatctccatgctggaaaagatctacatccaccccaggtacaactggagggagaacttg gaccgtgacatagccctgctgaggctcaagaagcccattgccttcagcaactacatccac cccgtgtgcctgcctgacaaggacaccgcagtcagactgctccgcgcgggatacaaagga cgggtgaccggctggggcaacctgaaggagatgtggacgtccagcgtgacagaggtgcag cccagcgtcctgcaggtggtgaacctccccatcgtggagcggccggtgtgcaaggcctcc actcggatccgcatcaccgacaacatgttctgtgctggtttcaagcccaatgaagggaaa cgaggggatgcttgtgaaggcgacagtgggggaccctttgtcatgaagagcccctttaac aaccgctggtatcaaatgggcatcgtctcatggggtgaaggctgtgacagggatggaaaa tatggcttctacacacacgtgttccgcctgaagaagtggatacagaaggtcattgatcag tctggaagctag

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