Ursus maritimus (polar bear): 103682334 Help Entry 103682334         CDS       T03271                                  Name (RefSeq) steroid 21-hydroxylase   KO K00513   steroid 21-monooxygenase [EC:1.14.14.16] Organism umr  Ursus maritimus (polar bear) Pathway umr00140   Steroid hormone biosynthesis umr01100   Metabolic pathways umr04925   Aldosterone synthesis and secretion umr04927   Cortisol synthesis and secretion umr04934   Cushing syndrome Module umr_M00109   C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     103682334  09150 Organismal Systems   09152 Endocrine system    04925 Aldosterone synthesis and secretion     103682334    04927 Cortisol synthesis and secretion     103682334  09160 Human Diseases   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103682334  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:umr00199]     103682334 Enzymes [BR:umr01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.16  steroid 21-monooxygenase      103682334 Cytochrome P450 [BR:umr00199]  Cytochrome P450, animal type   CYP21 family    103682334 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 PapZ_C Motif Other DBs NCBI-GeneID:  103682334 NCBI-ProteinID:  XP_040500553 UniProt:  A0A8M1GXT5 LinkDB All DBs Position Unknown AA seq 493 aa AA seqDB search MLLLGLLLLLTLLAGARLLWDKWQLRSLHLPPLVPGFLHLLQPNLPLYLLGLTRKLGPVY RLRLGLRDVVVLNSKRTIEEAMIRKWVDFAGRPQTLSYQLVSQHDQDLSLGDYSLLWKAH KKLTRSALLLGLRSSTELLVEQLTQEFCERMRAQAGAPVAIQKEFSFLTCTIICHLTFGD KEDTLVHAFHDCVQDLMKTWEHWSIQILDIVPFLRFLPNPGLWRLKQALENRDHMVEKQL RQHKESMVAGQWRDMTDYMLQRVGKPRAEEGHGQLLEGHVHMSVVDLFIGGTETTATTLS WAVAFLLHHPEIQRRLQEELDRELGPGASGSRVPYRDPARLPLLTATIAEVLRLRPVVPL ALPHRTTRPSSILGYDIPEGTVVIPNLQGAHLDETVWERPHEFRPDRFLVPGASPRVLAF GCGARVCLGEPLARLELFVVLAQLLRAFTLRPPAGALPSLQPRARCGVNLTVQPFQVQLQ PRGAAAGALGQHP NT seq 1482 nt NT seq  +upstreamnt  +downstreamnt atgctcctcctcgggctgctgctgctgctgaccctgctggctggcgcccgcctgctgtgg gacaagtggcagctccgcagcctccacctcccaccccttgtgcccggcttcctgcacctg ctgcagcccaaccttcccctctatctgctgggtctgacccggaaactggggcctgtctac aggctccgcctggggttgcgagatgtggtggtgctgaactccaagaggaccatcgaggaa gccatgatcaggaaatgggtggactttgccggcagaccccagacgctgtcctatcagctg gtgtctcagcatgaccaggacctctcccttggggactactccctgctctggaaggctcac aagaagctcacccgctcggccctgctgctgggcctccgcagctccacggagctgctggtg gagcagctgacccaggagttctgcgagcgcatgagagcccaggccggagcccccgtggcc atccagaaggagttctctttcctcacctgcaccatcatctgtcacctcacctttggagac aaggaggacaccttagtacatgcctttcatgactgtgtccaagacttgatgaaaacctgg gagcactggtccatccaaattttggacatcgttccctttctcaggttcctccccaaccca ggcctctggaggctgaagcaggccttggagaacagggaccacatggtagagaagcagctg cggcagcacaaggagagcatggtggcaggccagtggagggacatgacggactatatgctc cagagagtggggaagccaagagcagaagagggccacgggcagctgcttgaagggcacgtg catatgtctgtggtggacctgttcattggcggcacggagaccacggcgaccaccctctcc tgggccgtggcgttcttgcttcaccaccctgagattcagcggcgactccaggaagagctg gatcgtgagttgggccctggagcctcaggctcccgagtcccgtacagagaccctgcacgg ctgcccttgctcacagccaccatcgccgaggtgctgcgcctgcggcctgtcgtgcccctg gccttgccacaccgcaccacgcggcctagcagcatcttgggctacgacatccccgagggc acggttgtcatccccaacctgcaaggcgcccacttagacgagacggtctgggagcggcca cacgagttccggccggatcgtttcctggtccccggcgccagccccagagtgctggccttt ggctgcggggcgcgcgtgtgcctgggggagccgctggcgcgcctggagctcttcgtggtg ctggcgcagctgctgcgggccttcacgctgcggccgcccgccggcgccctgccctccctg cagccgcgcgcccgctgcggcgtcaacctcaccgtgcagcccttccaggtgcagctgcag ccccggggggccgcggccggggcgctgggccagcacccgtga

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