KEGG   Xenopus laevis (African clawed frog): 443571
Entry
443571            CDS       T01010                                 
Symbol
akr1c3.L
Name
(RefSeq) aldo-keto reductase family 1 member C3
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00140  Steroid hormone biosynthesis
xla00590  Arachidonic acid metabolism
xla00790  Folate biosynthesis
xla01100  Metabolic pathways
Module
xla_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
xla_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    443571 (akr1c3.L)
   00590 Arachidonic acid metabolism
    443571 (akr1c3.L)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    443571 (akr1c3.L)
Enzymes [BR:xla01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     443571 (akr1c3.L)
    1.1.1.188  prostaglandin-F synthase
     443571 (akr1c3.L)
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     443571 (akr1c3.L)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     443571 (akr1c3.L)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 443571
NCBI-ProteinID: XP_018096360
Xenbase: XB-GENE-5821995
UniProt: A0A8J0U3T7
LinkDB
Position
3L:complement(6684051..6688388)
AA seq 324 aa
MALHKDSYVELNDGHKMPVLGFGTYAPQKFPKNLAEEGTKVAIDVGYRHIDGAFLYGNEV
EVGRAIRAKIADGTVKREQLFYTGKLWSTFHTPEMVRPALEKSLKDLQLDYMDLFIIHTP
MEFKPGDDIFPVDENGKFIYHNTDIRDTWKALEECKDSGLVRSIGVSNFNHKQLELILNM
PGLKYKPVCNQVECHVYLNQSKLLEFCKSNDIVLVGYSVLGSSRDERWIEPSAPVLLEDP
VLNAIAKKHNCTTAQVAMRYHLQRGVIVLAKSFTPSRIQQNFQIFDFRLDAEDMRRIDAL
NRNMRYFDTSKLTDHPKYPYSEEY
NT seq 975 nt   +upstreamnt  +downstreamnt
atggcgctgcacaaggactcctacgttgagctcaatgatgggcacaaaatgccagtgctt
ggttttggcacttatgcccctcagaagttccccaagaacttggcagaggagggcaccaaa
gtggccattgatgttggataccgccatattgacggcgcttttctctacgggaacgaggtg
gaggttggacgggcgataagagcaaagattgccgatggtacagtgaagagggagcaattg
ttttacactgggaagctctggtccaccttccatacccctgagatggtccgtccagccctg
gagaaatctctgaaggatcttcagttggattacatggatctcttcatcattcataccccc
atggagttcaagcctggagatgatatctttccggtggatgaaaatgggaaatttatttac
cataatacagacattagagacacatggaaggcactggaagagtgcaaagactccgggctg
gtcagatccatcggggtgtccaattttaaccacaagcagctggagctgatcctcaatatg
cctggcctgaaatataaacccgtctgtaaccaggtggaatgtcacgtgtacctgaaccag
agcaaactgctggagttctgcaagtccaatgacattgtgctggtggggtacagcgtattg
gggtccagcagggatgagcgatggattgaaccaagcgcccctgtgctcttggaagacccc
gtactgaatgcgattgctaaaaagcacaactgcaccactgctcaggtagcaatgcggtac
catctccaaagaggagtcatcgtccttgcaaagagctttaccccttccaggatccagcag
aacttccagattttcgactttcggttggacgcagaagacatgagacgcatcgacgcacta
aacagaaacatgcgctacttcgacacatccaagttgacggaccacccgaaatacccctac
agtgaggaatactga

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