Zalophus californianus (California sea lion): 113914758
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Entry
113914758 CDS
T07874
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00350
Tyrosine metabolism
zca00790
Folate biosynthesis
zca01100
Metabolic pathways
zca04728
Dopaminergic synapse
zca04917
Prolactin signaling pathway
zca05012
Parkinson disease
zca05030
Cocaine addiction
zca05031
Amphetamine addiction
zca05034
Alcoholism
Module
zca_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
113914758 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
113914758 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
113914758 (TH)
09156 Nervous system
04728 Dopaminergic synapse
113914758 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
113914758 (TH)
09165 Substance dependence
05030 Cocaine addiction
113914758 (TH)
05031 Amphetamine addiction
113914758 (TH)
05034 Alcoholism
113914758 (TH)
Enzymes [BR:
zca01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
113914758 (TH)
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Gene cluster
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
113914758
NCBI-ProteinID:
XP_027436057
EnsemblRapid:
ENSZCAG00025013010
UniProt:
A0A6J2C0F9
LinkDB
All DBs
Position
11:111820271..111828494
Genome browser
AA seq
495 aa
AA seq
DB search
MPTPSSASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIEDARKEREKAEALSAASS
EPGDPLEAAVFKDKDGKAVLNLLFTLRGAKAASLSRAVKAFETFEAQIHHLETRPAQKPR
AGGPHLEYFVRCEVPSADLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTK
FDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGL
YVTHACREHLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLAS
LAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDKE
IEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPY
QDQTYQSVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLEGV
QDELHTLTHALSTIS
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagctccgcctcgccccaggccaagggcttccgcagggcggtctccgag
ctggatgccaagcaggccgaagccatcatgtccccacgcttcgtcgggcggcgacagagc
ctcatcgaggacgctcgcaaggagcgggagaaggccgaggccttgtcggccgcctcctcg
gagcccggggaccccctagaggccgcagtgttcaaggacaaggacgggaaggccgtgctg
aatctgctcttcaccctacggggcgccaaggccgcgtctctgtcccgggccgtgaaggca
tttgagacgtttgaagcccaaatccaccatctggagacccggcccgcccagaagccacgg
gcagggggcccccacctggagtactttgtgcgctgtgaggtgcccagcgctgacctgccc
gccctgctcagctctgtgcgccgggtggcggaggacgtgcgtggcgctggggagaacaag
gtcctctggttcccgaggaaagtttctgagctggacaagtgtcaccatctggtcaccaag
tttgaccctgacctggacttggatcatccgggcttctcggaccaggcgtaccgccagcgc
cggaagctgatcgcggagatcgcgttccagtacaagcacggcgaccctattccccgcgtg
gagtacacggccgaggagattgccacctggaaggaggtctacaccaccctcaagggcctc
tacgtcacacacgcctgccgggagcacctggaggccttccagttgctggagcgcttcagc
ggctaccgggaggacagcatcccccagctggaggatgtgtcccgcttcctgaaggagcgg
acgggcttccagctgcggcccgtggccggcctgctgtccgccagggacttcctggccagc
ctggccttccgagtgttccagtgcacccagtacatccgacacgcgtcctcgccaatgcac
tcccccgagccggactgttgccatgagctgctggggcacgtgcccatgctggccgaccgg
acctttgctcagttctcccaggacatcgggctcgcgtccttgggcgcttctgacaaggaa
atcgagaagctgtccacgctgtactggtttacggtggagttcgggctgtgtaagcagaat
ggcgaggtgaaggcctacggtgctgggctactgtcctcctacggggagctcctgcactcc
ctgtctgaggagcctgagatccgggccttcgaccccgacgctgcagccgtgcagccctac
caggaccagacctaccagtccgtgtactttgtgtctgaaagtttcagcgacgccaaggac
aagctcaggaactacgcttcccgcatccaacgccccttctctgtgaagtttgacccgtat
accctggccatcgacgtgctggacagtccccatgcgatccggcgctccctggagggcgtc
caggatgagctgcacaccctcacccacgcgctgagcaccatcagctag
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