KEGG pathway modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:T30899_00010 T30899_01200 T30899_01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:T30899_00010 T30899_01200 T30899_01230 T30899_01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:T30899_00010 T30899_00020 T30899_01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:T30899_00010 T30899_00020 T30899_00620 T30899_00785 T30899_01200 T30899_01210 T30899_01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:T30899_00020 T30899_01200 T30899_01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:T30899_00020 T30899_01200 T30899_01210 T30899_01230 T30899_01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:T30899_00020 T30899_01200 T30899_01210 T30899_01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:T30899_00030 T30899_01200 T30899_01100 T30899_01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P [PATH:T30899_00030 T30899_01200 T30899_01100 T30899_01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P [PATH:T30899_00030 T30899_01200 T30899_01230 T30899_01100 T30899_01120]
M00580 Pentose phosphate pathway, archaea, fructose-6P => ribose-5P [PATH:T30899_00030 T30899_01200 T30899_01230 T30899_01100 T30899_01120]
M00005 PRPP biosynthesis, ribose-5P => PRPP [PATH:T30899_00030 T30899_00230 T30899_01200 T30899_01230 T30899_01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:T30899_00030 T30899_01200 T30899_01100 T30899_01120]

Other carbohydrate metabolism
M00552 Galactonate degradation, De Ley-Doudoroff pathway, galactonate => glycerate-3P [PATH:T30899_00052 T30899_01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:T30899_00500 T30899_01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:T30899_00500 T30899_01100]
M00012 Glyoxylate cycle [PATH:T30899_00630 T30899_01200 T30899_01100 T30899_01110]
M00373 Ethylmalonyl pathway [PATH:T30899_00630 T30899_01200 T30899_01100 T30899_01120]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:T30899_00280 T30899_00630 T30899_00640 T30899_01200 T30899_01100]
M00982 Methylcitrate cycle [PATH:T30899_00640 T30899_00020 T30899_01200 T30899_01100 T30899_01120]

Energy metabolism
Carbon fixation
M00165 Reductive pentose phosphate cycle (Calvin cycle) [PATH:T30899_00710 T30899_01200 T30899_01100 T30899_01120]
M00168 CAM (Crassulacean acid metabolism), dark [PATH:T30899_00620 T30899_00710 T30899_01200 T30899_01100 T30899_01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:T30899_00620 T30899_00710 T30899_01200 T30899_01100 T30899_01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:T30899_00430 T30899_00620 T30899_00720 T30899_01200 T30899_01100 T30899_01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:T30899_00030 T30899_00680 T30899_01200 T30899_01230 T30899_01100 T30899_01120]

Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:T30899_00910 T30899_01310 T30899_01100 T30899_01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:T30899_00910 T30899_01310 T30899_01100 T30899_01120]
M00529 Denitrification, nitrate => nitrogen [PATH:T30899_00910 T30899_01310 T30899_01100 T30899_01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:T30899_00920 T30899_01320 T30899_01100 T30899_01120]
M00595 Sulfur oxidation, SOX system, thiosulfate => sulfate [PATH:T30899_00920 T30899_01320 T30899_01100 T30899_01120]

Photosynthesis
M00597 Anoxygenic photosystem II

ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:T30899_00190 T30899_01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:T30899_00190 T30899_01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:T30899_00190 T30899_01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:T30899_00190 T30899_01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:T30899_00190 T30899_01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:T30899_00190 T30899_01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:T30899_00190 T30899_00195 T30899_01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:T30899_00061 T30899_01212 T30899_01100]
M00083 Fatty acid biosynthesis, elongation [PATH:T30899_00061 T30899_01212 T30899_01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:T30899_00061 T30899_00071 T30899_01212 T30899_01100]
M00087 beta-Oxidation [PATH:T30899_00071 T30899_01212 T30899_01100]

Sterol biosynthesis
Lipid metabolism
M00098 Acylglycerol degradation [PATH:T30899_00561 T30899_01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:T30899_00564 T30899_01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:T30899_00564 T30899_01100]
M00100 Sphingosine degradation [PATH:T30899_00600 T30899_01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:T30899_00230 T30899_01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:T30899_00230 T30899_01232 T30899_01240 T30899_01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:T30899_00230 T30899_01232 T30899_01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:T30899_00230 T30899_00240 T30899_01232 T30899_01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:T30899_00230 T30899_01232 T30899_01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:T30899_00230 T30899_01232 T30899_01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:T30899_00240 T30899_01240 T30899_01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:T30899_00240 T30899_01232 T30899_01240 T30899_01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:T30899_00240 T30899_01232 T30899_01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:T30899_00240 T30899_00410 T30899_00770 T30899_01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:T30899_00260 T30899_00680 T30899_01200 T30899_01230 T30899_01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:T30899_00260 T30899_01230 T30899_01100 T30899_01110]
M00621 Glycine cleavage system [PATH:T30899_00260 T30899_00630 T30899_00670 T30899_00785 T30899_01200 T30899_01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:T30899_00260 T30899_00670 T30899_01100]
M00975 Betaine degradation, bacteria, betaine => pyruvate [PATH:T30899_00260 T30899_01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:T30899_00260 T30899_01210 T30899_01230 T30899_01100 T30899_01120]
M00919 Ectoine degradation, ectoine => aspartate [PATH:T30899_00260 T30899_01100 T30899_01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:T30899_00270 T30899_00920 T30899_01320 T30899_01200 T30899_01230 T30899_01100 T30899_01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:T30899_00260 T30899_00270 T30899_00670 T30899_01230 T30899_01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:T30899_00270 T30899_01230 T30899_01100]
M00035 Methionine degradation [PATH:T30899_00270 T30899_00670 T30899_01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:T30899_00290 T30899_00770 T30899_01210 T30899_01230 T30899_01100 T30899_01110]
M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:T30899_00290 T30899_00660 T30899_01210 T30899_01230 T30899_01100]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:T30899_00290 T30899_01230 T30899_01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:T30899_00290 T30899_01210 T30899_01230 T30899_01100 T30899_01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:T30899_00280 T30899_01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:T30899_00300 T30899_01230 T30899_01100]
M00957 Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA [PATH:T30899_00310 T30899_01100 T30899_01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:T30899_00220 T30899_01210 T30899_01230 T30899_01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:T30899_00220 T30899_01230 T30899_01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:T30899_00330 T30899_01230 T30899_01100]
M00970 Proline degradation, proline => glutamate [PATH:T30899_00330 T30899_01100]
M00972 Proline metabolism [PATH:T30899_00330 T30899_01100]
M00047 Creatine pathway [PATH:T30899_00330 T30899_00260 T30899_01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:T30899_00330 T30899_01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:T30899_00330 T30899_01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:T30899_00330 T30899_01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:T30899_00340 T30899_01230 T30899_01100 T30899_01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:T30899_00340 T30899_01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:T30899_00400 T30899_01230 T30899_01100 T30899_01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:T30899_00400 T30899_01230 T30899_01100 T30899_01110]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:T30899_00380 T30899_01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:T30899_00250 T30899_00650 T30899_01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:T30899_00480 T30899_01240 T30899_01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:T30899_00520 T30899_01250 T30899_01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:T30899_00520 T30899_01250 T30899_01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:T30899_00520 T30899_01250 T30899_01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:T30899_00520 T30899_00052 T30899_01250 T30899_01100]
M00997 UDP-Xyl/L-Ara biosynthesis, UDP-Glc => UDP-Xyl => UDP-L-Ala [PATH:T30899_00520 T30899_01250 T30899_01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:T30899_00520 T30899_00053 T30899_01250 T30899_01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:T30899_00520 T30899_00051 T30899_01250 T30899_01100]
M01015 GDP-Man biosynthesis, Man => GDP-Man [PATH:T30899_00520 T30899_00051 T30899_01250 T30899_01100]
M01036 UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA [PATH:T30899_00541 T30899_01250 T30899_01100]
M01035 UDP-ManNAc3NAcA biosynthesis, UDP-GlcNAc => UDP-ManNAc3NAcA [PATH:T30899_00541 T30899_01250 T30899_01100]
M01009 UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc [PATH:T30899_00541 T30899_01250 T30899_01100]
M01011 CMP-Leg5Ac7Ac biosynthesis, UDP-BacNAc4NAc => CMP-Leg5Ac7Ac [PATH:T30899_00541 T30899_01250 T30899_01100]
M00063 CMP-KDO biosynthesis, ribulose-5P => CMP-KDO [PATH:T30899_00541 T30899_01250 T30899_01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:T30899_00541 T30899_01250 T30899_01100]
M00064 ADP-LDmanHep biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:T30899_00541 T30899_01250 T30899_01100]
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha [PATH:T30899_00521 T30899_00523 T30899_00541 T30899_01250 T30899_01100 T30899_01110]
M01006 GDP-D-Rha4N biosynthesis, Fru-6P => GDP-D-Rha4N [PATH:T30899_00520 T30899_00541 T30899_01250 T30899_01100]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:T30899_00541 T30899_00051 T30899_01250 T30899_01100]
M01018 GDP-D-Rha biosynthesis, GDP-Man => GDP-D-Rha [PATH:T30899_00541 T30899_00051 T30899_01250 T30899_01100]

Glycan biosynthesis
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:T30899_00601 T30899_01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:T30899_00601 T30899_01100]

Glycosaminoglycan metabolism
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:T30899_00532 T30899_01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:T30899_00730 T30899_01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:T30899_00740 T30899_01240 T30899_01100 T30899_01110]
M00124 Pyridoxal phosphate biosynthesis, erythrose-4P => pyridoxal-P [PATH:T30899_00750 T30899_01240 T30899_01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:T30899_00760 T30899_01240 T30899_01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:T30899_00380 T30899_00760 T30899_01240 T30899_01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:T30899_00770 T30899_01240 T30899_01100 T30899_01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:T30899_00770 T30899_01240 T30899_01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:T30899_00780 T30899_01240 T30899_01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:T30899_00780 T30899_01240 T30899_01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:T30899_00785 T30899_01240 T30899_01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:T30899_00790 T30899_00670 T30899_01240 T30899_01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:T30899_00790 T30899_01240 T30899_01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:T30899_00790 T30899_01100]
M00140 C1-unit interconversion, prokaryotes [PATH:T30899_00670 T30899_01240 T30899_01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:T30899_00860 T30899_01240 T30899_01100 T30899_01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:T30899_00860 T30899_01240 T30899_01100 T30899_01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:T30899_00860 T30899_01240 T30899_01100 T30899_01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:T30899_00860 T30899_01240 T30899_01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:T30899_00860 T30899_01240 T30899_01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:T30899_00130 T30899_01240 T30899_01100 T30899_01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:T30899_00130 T30899_01240 T30899_01100 T30899_01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:T30899_00130 T30899_01240 T30899_01100 T30899_01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:T30899_00900 T30899_01100 T30899_01110]

Terpenoid biosynthesis
M00097 Lycopene biosynthesis, geranylgeranyl-PP => lycopene [PATH:T30899_00906 T30899_01100 T30899_01110]
M01045 Zeaxanthin biosynthesis, lycopene => beta-carotene => zeaxanthin [PATH:T30899_00906 T30899_01100 T30899_01110]

Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Biosynthesis of other compounds
Xenobiotics biodegradation
Aromatics degradation
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:T30899_00362 T30899_01220 T30899_01100 T30899_01120]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:T30899_00362 T30899_00622 T30899_01220 T30899_01100 T30899_01120]
M00623 Phthalate degradation, phthalate => protocatechuate [PATH:T30899_00624 T30899_01220 T30899_01100 T30899_01120]
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:T30899_00360 T30899_01220 T30899_01100 T30899_01120]

Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:T30899_01501]
M00642 Multidrug resistance, efflux pump MexJK-OprM

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00612 Anoxygenic photosynthesis in purple bacteria
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation