KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:abe00010 abe01200 abe01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:abe00010 abe01200 abe01230 abe01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:abe00010 abe00020 abe01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:abe00020 abe01200 abe01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:abe00020 abe01200 abe01210 abe01230 abe01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:abe00020 abe01200 abe01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:abe00030 abe01200 abe01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:abe00030 abe01200 abe01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:abe00030 abe01200 abe01230 abe01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:abe00030 abe00230 abe01200 abe01230 abe01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:abe00052 abe01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:abe00500 abe01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:abe00500 abe01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:abe00520 abe01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:abe00520 abe00052 abe01100]
M00012 Glyoxylate cycle [PATH:abe00630 abe01200 abe01100 abe01110]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH:abe00410 abe00640 abe01200 abe01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:abe00920 abe01100]

Photosynthesis
ATP synthesis
M00148 Succinate dehydrogenase (ubiquinone) [PATH:abe00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:abe00061 abe01212 abe01100]
M00083 Fatty acid biosynthesis, elongation [PATH:abe00061 abe01212 abe01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:abe00061 abe00071 abe01212 abe01100]

Sterol biosynthesis
M00102 Ergocalciferol biosynthesis [PATH:abe00100 abe01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:abe00561 abe01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:abe00564 abe01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:abe00564 abe01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:abe00564 abe01100]
M00094 Ceramide biosynthesis [PATH:abe00600 abe01100]
M00099 Sphingosine biosynthesis [PATH:abe00600 abe01100]
M00100 Sphingosine degradation [PATH:abe00600 abe01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:abe00230 abe01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:abe00230 abe01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:abe00230 abe01100]

Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:abe00240 abe01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:abe00240 abe01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:abe00260 abe00680 abe01200 abe01230 abe01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:abe00260 abe01230 abe01100 abe01110]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:abe00260 abe00270 abe01230 abe01100]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:abe00270 abe01230 abe01100]
M00035 Methionine degradation [PATH:abe00270 abe01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:abe00290 abe00770 abe01210 abe01230 abe01100 abe01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:abe00290 abe01230 abe01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:abe00290 abe01210 abe01230 abe01100 abe01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:abe00280 abe01100]

Lysine metabolism
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:abe00300 abe01230 abe01100]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:abe00300 abe01210 abe01230 abe01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:abe00220 abe01210 abe01230 abe01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:abe00220 abe01230 abe01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:abe00330 abe01230 abe01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:abe00330 abe01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:abe00340 abe01230 abe01100 abe01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:abe00400 abe01230 abe01100 abe01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:abe00400 abe01230 abe01100 abe01110]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:abe00350 abe01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:abe00250 abe00650 abe01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:abe00480 abe01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:abe00510 abe01100]
M00073 N-glycan precursor trimming [PATH:abe00510 abe01100]

Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:abe00780 abe01100]
M00141 C1-unit interconversion, eukaryotes [PATH:abe00670 abe01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:abe00860 abe01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:abe00900 abe01100 abe01110]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:abe00900 abe01100 abe01110]

Other terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
beta-Lactam biosynthesis
M00672 Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin [PATH:abe00311 abe01100]

Biosynthesis of other secondary metabolites
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity