KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:aso00010 aso01200 aso01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:aso00010 aso01200 aso01230 aso01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:aso00010 aso00020 aso01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:aso00010 aso00020 aso00620 aso01200 aso01210 aso01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:aso00020 aso01200 aso01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:aso00020 aso01200 aso01210 aso01230 aso01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:aso00020 aso01200 aso01210 aso01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:aso00030 aso01200 aso01100 aso01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:aso00030 aso01200 aso01100 aso01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:aso00030 aso01200 aso01230 aso01100 aso01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:aso00030 aso00230 aso01200 aso01230 aso01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:aso00052 aso01100]
M00012 Glyoxylate cycle [PATH:aso00630 aso01200 aso01100 aso01110]
M00982 Methylcitrate cycle [PATH:aso00640 aso00020 aso01200 aso01100 aso01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:aso00620 aso00710 aso01200 aso01100 aso01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:aso00430 aso00620 aso00720 aso01200 aso01100 aso01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:aso00190 aso01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:aso00190 aso01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:aso00190 aso01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:aso00190 aso01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:aso00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:aso00190 aso01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:aso00190 aso01100]
M00159 V/A-type ATPase, prokaryotes [PATH:aso00190 aso01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:aso00061 aso01212 aso01100]
M00083 Fatty acid biosynthesis, elongation [PATH:aso00061 aso01212 aso01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:aso00061 aso00071 aso01212 aso01100]
M00087 beta-Oxidation [PATH:aso00071 aso01212 aso01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:aso00564 aso01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aso00230 aso01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aso00230 aso01232 aso01240 aso01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aso00230 aso01232 aso01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aso00230 aso00240 aso01232 aso01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:aso00230 aso01232 aso01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:aso00230 aso01232 aso01100]
M00546 Purine degradation, xanthine => urea [PATH:aso00230 aso01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:aso00240 aso01232 aso01240 aso01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:aso00240 aso01232 aso01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:aso00260 aso00680 aso01200 aso01230 aso01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:aso00260 aso01230 aso01100 aso01110]
M00621 Glycine cleavage system [PATH:aso00260 aso00630 aso00670 aso01200 aso01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:aso00260 aso00670 aso01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:aso00270 aso01200 aso01230 aso01100 aso01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:aso00270 aso01230 aso01100]
M00034 Methionine salvage pathway [PATH:aso00270 aso01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:aso00290 aso00770 aso01210 aso01230 aso01100 aso01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:aso00290 aso01230 aso01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:aso00290 aso01210 aso01230 aso01100 aso01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:aso00300 aso01230 aso01100]
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:aso00300 aso01230 aso01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:aso00300 aso01230 aso01100 aso01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:aso00220 aso01210 aso01230 aso01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:aso00220 aso01230 aso01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:aso00330 aso01230 aso01100]
M00970 Proline degradation, proline => glutamate [PATH:aso00330 aso01100]
M00972 Proline metabolism [PATH:aso00330 aso01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:aso00330 aso01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:aso00330 aso01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:aso01230 aso01100 aso01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:aso01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:aso00400 aso01230 aso01100 aso01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:aso00400 aso01230 aso01100 aso01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:aso00400 aso01230 aso01100 aso01110]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:aso00400 aso01230 aso01100 aso01110]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:aso00350 aso01220 aso01100 aso01120]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:aso00250 aso00650 aso01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:aso00480 aso01240 aso01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:aso00520 aso01250 aso01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:aso00520]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:aso00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:aso00520 aso01250 aso01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:aso00520 aso00052]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:aso00520 aso00052 aso01250 aso01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:aso00520]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:aso00541 aso01250 aso01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:aso00521 aso00541 aso01250 aso01100 aso01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:aso00730 aso01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:aso01240 aso01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:aso00760 aso01240 aso01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:aso00770 aso01240 aso01100 aso01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:aso00770 aso01240 aso01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:aso00780 aso01240 aso01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:aso00780 aso01240 aso01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:aso00780 aso01240 aso01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:aso01240 aso01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:aso01240 aso01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:aso00790 aso01240 aso01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:aso00790 aso01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:aso00860 aso01240 aso01100 aso01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:aso00860 aso01240 aso01100 aso01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:aso00860 aso01240 aso01100]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:aso00860 aso01240 aso01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:aso00860 aso01240 aso01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:aso00900 aso01100 aso01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:aso00900 aso01100 aso01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:aso01220 aso01100 aso01120]
M00637 Anthranilate degradation, anthranilate => catechol [PATH:aso01100 aso01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:aso01220 aso01100 aso01120]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:aso01220 aso01100 aso01120]

Gene set
Pathogenicity
Drug resistance
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00649 Multidrug resistance, efflux pump AdeABC [PATH:aso01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity