KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:blh00010 blh01200 blh01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:blh00010 blh01200 blh01230 blh01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:blh00010 blh00020 blh01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:blh00010 blh00020 blh00620 blh00785 blh01200 blh01210 blh01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:blh00020 blh01200 blh01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:blh00020 blh01200 blh01210 blh01230 blh01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:blh00020 blh01200 blh01210 blh01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:blh00030 blh01200 blh01100 blh01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:blh00030 blh01200 blh01100 blh01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:blh00030 blh01200 blh01230 blh01100 blh01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:blh00030 blh00230 blh01200 blh01230 blh01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:blh00040 blh00030 blh01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:blh00052 blh01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:blh00500 blh01100]
M00012 Glyoxylate cycle [PATH:blh00630 blh01200 blh01100 blh01110]
M00982 Methylcitrate cycle [PATH:blh00640 blh00020 blh01200 blh01100 blh01120]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:blh00430 blh00620 blh00720 blh01200 blh01100 blh01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:blh00030 blh00680 blh01200 blh01230 blh01100 blh01120]

Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:blh00910 blh01310 blh01100 blh01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:blh00920 blh01320 blh01100 blh01120]

Photosynthesis
ATP synthesis
M00151 Cytochrome bc1 complex respiratory unit [PATH:blh00190 blh01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:blh00190 blh01100]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:blh00190 blh01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:blh00190 blh01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:blh00061 blh01212 blh01100]
M00083 Fatty acid biosynthesis, elongation [PATH:blh00061 blh01212 blh01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:blh00061 blh00071 blh01212 blh01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:blh00564 blh01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:blh00230 blh01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:blh00230 blh01232 blh01240 blh01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:blh00230 blh01232 blh01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:blh00230 blh00240 blh01232 blh01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:blh00240 blh01232 blh01240 blh01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:blh00260 blh00680 blh01200 blh01230 blh01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:blh00260 blh01230 blh01100 blh01110]
M00621 Glycine cleavage system [PATH:blh00260 blh00630 blh00670 blh00785 blh01200 blh01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:blh00260 blh00670 blh01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:blh00270 blh00920 blh01320 blh01200 blh01230 blh01100 blh01110]
M00609 Cysteine biosynthesis, methionine => cysteine [PATH:blh00270 blh01230 blh01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:blh00270 blh01230 blh01100]
M00034 Methionine salvage pathway [PATH:blh00270 blh01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:blh00290 blh00770 blh01210 blh01230 blh01100 blh01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:blh00290 blh01230 blh01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:blh00290 blh01210 blh01230 blh01100 blh01110]

Lysine metabolism
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:blh00300 blh01230 blh01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:blh00220 blh01210 blh01230 blh01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:blh00220 blh01230 blh01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:blh00330 blh01230 blh01100]
M00970 Proline degradation, proline => glutamate [PATH:blh00330 blh01100]
M00972 Proline metabolism [PATH:blh00330 blh01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:blh00330 blh01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:blh00340 blh01230 blh01100 blh01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:blh00400 blh01230 blh01100 blh01110]

Other amino acid metabolism
Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:blh00520 blh01250 blh01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:blh00520 blh01250 blh01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:blh00520 blh01250 blh01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:blh00520 blh00052 blh01250 blh01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00895 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP [PATH:blh00730 blh01240 blh01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:blh00730 blh01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:blh00740 blh01240 blh01100 blh01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:blh00750 blh01240 blh01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:blh00760 blh01240 blh01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:blh00770 blh01240 blh01100 blh01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:blh00770 blh01240 blh01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:blh00780 blh01240 blh01100]
M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin [PATH:blh00780 blh01240 blh01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:blh00780 blh01240 blh01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:blh00785 blh01240 blh01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:blh00790 blh00670 blh01240 blh01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:blh00790 blh01240 blh01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:blh00790 blh01100]
M00140 C1-unit interconversion, prokaryotes [PATH:blh00670 blh01240 blh01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:blh00860 blh01240 blh01100 blh01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:blh00860 blh01240 blh01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:blh00130 blh01240 blh01100 blh01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:blh00900 blh01100 blh01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:blh00900 blh01100 blh01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
M00877 Kanosamine biosynthesis, glucose 6-phosphate => kanosamine [PATH:blh00998 blh01100 blh01110]

Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:blh01501]
M00700 Multidrug resistance, efflux pump AbcA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation