KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:bvi00010 bvi01200 bvi01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bvi00010 bvi01200 bvi01230 bvi01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bvi00010 bvi00020 bvi01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bvi00010 bvi00020 bvi00620 bvi00785 bvi01200 bvi01210 bvi01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bvi00020 bvi01200 bvi01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bvi00020 bvi01200 bvi01210 bvi01230 bvi01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bvi00020 bvi01200 bvi01210 bvi01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bvi00030 bvi01200 bvi01100 bvi01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bvi00030 bvi01200 bvi01100 bvi01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bvi00030 bvi01200 bvi01230 bvi01100 bvi01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bvi00030 bvi00230 bvi01200 bvi01230 bvi01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:bvi00030 bvi01200 bvi01100 bvi01120]

Other carbohydrate metabolism
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:bvi00052 bvi01100]
M00012 Glyoxylate cycle [PATH:bvi00630 bvi01200 bvi01100 bvi01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bvi00280 bvi00630 bvi00640 bvi01200 bvi01100]
M00982 Methylcitrate cycle [PATH:bvi00640 bvi00020 bvi01200 bvi01100 bvi01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:bvi00620 bvi00710 bvi01200 bvi01100 bvi01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:bvi00620 bvi00710 bvi01200 bvi01100 bvi01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bvi00430 bvi00620 bvi00720 bvi01200 bvi01100 bvi01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:bvi00910 bvi01310 bvi01100 bvi01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:bvi00910 bvi01310 bvi01100 bvi01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:bvi00920 bvi01320 bvi01100 bvi01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:bvi00190 bvi01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:bvi00190 bvi01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:bvi00190 bvi01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bvi00190 bvi01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:bvi00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:bvi00190 bvi01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bvi00190 bvi01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bvi00061 bvi01212 bvi01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bvi00061 bvi01212 bvi01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bvi00061 bvi00071 bvi01212 bvi01100]
M00087 beta-Oxidation [PATH:bvi00071 bvi01212 bvi01100]

Sterol biosynthesis
Lipid metabolism
M00098 Acylglycerol degradation [PATH:bvi00561 bvi01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bvi00564 bvi01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bvi00230 bvi01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bvi00230 bvi01232 bvi01240 bvi01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bvi00230 bvi01232 bvi01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bvi00230 bvi00240 bvi01232 bvi01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:bvi00230 bvi01232 bvi01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:bvi00230 bvi01232 bvi01100]
M00546 Purine degradation, xanthine => urea [PATH:bvi00230 bvi01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:bvi00240 bvi01240 bvi01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bvi00240 bvi01232 bvi01240 bvi01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:bvi00240 bvi01232 bvi01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:bvi00240 bvi00410 bvi00770 bvi01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:bvi00260 bvi00680 bvi01200 bvi01230 bvi01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bvi00260 bvi01230 bvi01100 bvi01110]
M00621 Glycine cleavage system [PATH:bvi00260 bvi00630 bvi00670 bvi00785 bvi01200 bvi01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:bvi00260 bvi00670 bvi01100]
M00975 Betaine degradation, bacteria, betaine => pyruvate [PATH:bvi00260 bvi01100]
M00919 Ectoine degradation, ectoine => aspartate [PATH:bvi00260 bvi01100 bvi01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bvi00270 bvi00920 bvi01320 bvi01200 bvi01230 bvi01100 bvi01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:bvi00260 bvi00270 bvi00670 bvi01230 bvi01100]
M00035 Methionine degradation [PATH:bvi00270 bvi00670 bvi01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bvi00290 bvi00770 bvi01210 bvi01230 bvi01100 bvi01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bvi00290 bvi01230 bvi01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bvi00290 bvi01210 bvi01230 bvi01100 bvi01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:bvi00280 bvi01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:bvi00300 bvi01230 bvi01100]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:bvi00300 bvi01230 bvi01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bvi00220 bvi01210 bvi01230 bvi01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bvi00220 bvi01230 bvi01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bvi00330 bvi01230 bvi01100]
M00970 Proline degradation, proline => glutamate [PATH:bvi00330 bvi01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:bvi00330 bvi01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:bvi00340 bvi01230 bvi01100 bvi01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:bvi00340 bvi01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bvi00400 bvi01230 bvi01100 bvi01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:bvi00400 bvi01230 bvi01100 bvi01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:bvi00400 bvi01230 bvi01100 bvi01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:bvi00400 bvi01230 bvi01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:bvi00350 bvi01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:bvi00350 bvi01220 bvi01100 bvi01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:bvi00480 bvi01240 bvi01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:bvi00470 bvi01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:bvi00520 bvi01250 bvi01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:bvi00520 bvi01250 bvi01100 bvi01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:bvi00520 bvi01250 bvi01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:bvi00520 bvi01250 bvi01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:bvi00520 bvi00053 bvi01250 bvi01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:bvi00520 bvi01250 bvi01100]
M01036 UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA [PATH:bvi00541]
M01035 UDP-ManNAc3NAcA biosynthesis, UDP-GlcNAc => UDP-ManNAc3NAcA [PATH:bvi00541]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:bvi00541 bvi01250 bvi01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:bvi00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:bvi00541 bvi01250 bvi01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:bvi00521 bvi00523 bvi00541 bvi01250 bvi01100 bvi01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:bvi00730 bvi01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bvi00750 bvi01240 bvi01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bvi00760 bvi01240 bvi01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bvi00770 bvi01240 bvi01100 bvi01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bvi00770 bvi01240 bvi01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bvi00780 bvi01240 bvi01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:bvi00785 bvi01240 bvi01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bvi00790 bvi00670 bvi01240 bvi01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bvi00790 bvi01240 bvi01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:bvi00790 bvi01100]
M00140 C1-unit interconversion, prokaryotes [PATH:bvi00670 bvi01240 bvi01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:bvi00860 bvi01240 bvi01100 bvi01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:bvi00860 bvi01240 bvi01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:bvi00130 bvi01240 bvi01100 bvi01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00548 Benzene degradation, benzene => catechol [PATH:bvi00361 bvi00362 bvi01220 bvi01100 bvi01120]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:bvi00362 bvi00622 bvi01220 bvi01100 bvi01120]
M00637 Anthranilate degradation, anthranilate => catechol [PATH:bvi00627 bvi01100 bvi01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:bvi00362 bvi01220 bvi01100 bvi01120]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:bvi00362 bvi00622 bvi01220 bvi01100 bvi01120]
M00623 Phthalate degradation, phthalate => protocatechuate [PATH:bvi00624 bvi01220 bvi01100 bvi01120]
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:bvi00360 bvi01220 bvi01100 bvi01120]

Gene set
Pathogenicity
Drug resistance
M00643 Multidrug resistance, efflux pump MexXY-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation