KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:cbra00010 cbra01200 cbra01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:cbra00010 cbra01200 cbra01230 cbra01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:cbra00010 cbra00020 cbra01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:cbra00010 cbra00020 cbra00620 cbra00785 cbra01200 cbra01210 cbra01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:cbra00020 cbra01200 cbra01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:cbra00020 cbra01200 cbra01210 cbra01230 cbra01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:cbra00020 cbra01200 cbra01210 cbra01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:cbra00030 cbra01200 cbra01100 cbra01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:cbra00030 cbra01200 cbra01100 cbra01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:cbra00030 cbra01200 cbra01230 cbra01100 cbra01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:cbra00030 cbra00230 cbra01200 cbra01230 cbra01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:cbra00030 cbra01200 cbra01100 cbra01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:cbra00040 cbra00030 cbra01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:cbra00040 cbra00030 cbra01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:cbra00052 cbra01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:cbra00053 cbra01100 cbra01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:cbra00500 cbra01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:cbra00500 cbra01100]
M00012 Glyoxylate cycle [PATH:cbra00630 cbra01200 cbra01100 cbra01110]
M00982 Methylcitrate cycle [PATH:cbra00640 cbra00020 cbra01200 cbra01100 cbra01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:cbra00620 cbra00710 cbra01200 cbra01100 cbra01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:cbra00430 cbra00620 cbra00720 cbra01200 cbra01100 cbra01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:cbra00910 cbra01310 cbra01100 cbra01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:cbra00910 cbra01310 cbra01100 cbra01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:cbra00920 cbra01320 cbra01100 cbra01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:cbra00190 cbra01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:cbra00190 cbra01100]
M00150 Fumarate reductase, prokaryotes [PATH:cbra00190 cbra01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:cbra00190 cbra01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:cbra00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:cbra00190 cbra01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:cbra00190 cbra01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:cbra00061 cbra01212 cbra01100]
M00083 Fatty acid biosynthesis, elongation [PATH:cbra00061 cbra01212 cbra01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:cbra00061 cbra00071 cbra01212 cbra01100]
M00087 beta-Oxidation [PATH:cbra00071 cbra01212 cbra01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:cbra00564 cbra01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cbra00230 cbra01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cbra00230 cbra01232 cbra01240 cbra01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cbra00230 cbra01232 cbra01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cbra00230 cbra00240 cbra01232 cbra01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:cbra00240 cbra01240 cbra01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:cbra00240 cbra01232 cbra01240 cbra01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:cbra00240 cbra01232 cbra01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:cbra00260 cbra00680 cbra01200 cbra01230 cbra01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:cbra00260 cbra01230 cbra01100 cbra01110]
M00621 Glycine cleavage system [PATH:cbra00260 cbra00630 cbra00670 cbra00785 cbra01200 cbra01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:cbra00270 cbra00920 cbra01320 cbra01200 cbra01230 cbra01100 cbra01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:cbra00270 cbra01230 cbra01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:cbra00290 cbra00770 cbra01210 cbra01230 cbra01100 cbra01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:cbra00290 cbra01230 cbra01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:cbra00290 cbra01210 cbra01230 cbra01100 cbra01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:cbra00300 cbra01230 cbra01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:cbra00310 cbra01100 cbra01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:cbra00220 cbra01210 cbra01230 cbra01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:cbra00220 cbra01230 cbra01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:cbra00330 cbra01230 cbra01100]
M00970 Proline degradation, proline => glutamate [PATH:cbra00330 cbra01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:cbra00330 cbra01100]

Polyamine biosynthesis
M00136 GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:cbra00330 cbra01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:cbra00340 cbra01230 cbra01100 cbra01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:cbra00340 cbra01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:cbra00400 cbra01230 cbra01100 cbra01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:cbra00400 cbra01230 cbra01100 cbra01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:cbra00400 cbra01230 cbra01100 cbra01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:cbra00400 cbra01230 cbra01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:cbra00350 cbra01220 cbra01100 cbra01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:cbra00480 cbra01240 cbra01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:cbra00520 cbra01250 cbra01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:cbra00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:cbra00520 cbra01250 cbra01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:cbra00520 cbra00052 cbra01250 cbra01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:cbra00520]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:cbra00541 cbra01250 cbra01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:cbra00541 cbra01250 cbra01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:cbra00541 cbra01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:cbra00521 cbra00523 cbra00541 cbra01250 cbra01100 cbra01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:cbra00540 cbra01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:cbra00730 cbra01240 cbra01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:cbra00730 cbra01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:cbra00740 cbra01240 cbra01100 cbra01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:cbra00750 cbra01240 cbra01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:cbra00760 cbra01240 cbra01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:cbra00770 cbra01240 cbra01100 cbra01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:cbra00770 cbra01240 cbra01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:cbra00780 cbra01240 cbra01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:cbra00780 cbra01240 cbra01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:cbra00785 cbra01240 cbra01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:cbra00790 cbra00670 cbra01240 cbra01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:cbra00790 cbra01240 cbra01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:cbra00790 cbra01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:cbra00860 cbra01240 cbra01100 cbra01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:cbra00860 cbra01240 cbra01100 cbra01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:cbra00860 cbra01240 cbra01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:cbra00860 cbra01240 cbra01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:cbra00130 cbra01240 cbra01100 cbra01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:cbra00130 cbra01240 cbra01100 cbra01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:cbra00130 cbra01240 cbra01100 cbra01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:cbra00900 cbra01100 cbra01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:cbra00900 cbra01100 cbra01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
M00857 Salmonella enterica pathogenicity signature, Vi antigen

Drug resistance
M00696 Multidrug resistance, efflux pump AcrEF-TolC
M00697 Multidrug resistance, efflux pump MdtEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation