KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:daq00010 daq01200 daq01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:daq00010 daq01200 daq01230 daq01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:daq00010 daq00020 daq01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:daq00010 daq00020 daq00620 daq00785 daq01200 daq01210 daq01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:daq00020 daq01200 daq01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:daq00020 daq01200 daq01210 daq01230 daq01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:daq00020 daq01200 daq01210 daq01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:daq00030 daq01200 daq01100 daq01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:daq00030 daq01200 daq01100 daq01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:daq00030 daq01200 daq01230 daq01100 daq01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:daq00030 daq00230 daq01200 daq01230 daq01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:daq00040 daq00030 daq01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:daq00040 daq00030 daq01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:daq00052 daq01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:daq00053 daq01100 daq01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:daq00500 daq01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:daq00500 daq01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:daq00500 daq01100 daq01110]
M00012 Glyoxylate cycle [PATH:daq00630 daq01200 daq01100 daq01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:daq00620 daq00710 daq01200 daq01100 daq01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:daq00430 daq00620 daq00720 daq01200 daq01100 daq01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:daq00920 daq01320 daq01100 daq01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:daq00190 daq01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:daq00190 daq01100]
M00150 Fumarate reductase, prokaryotes [PATH:daq00190 daq01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:daq00190 daq01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:daq00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:daq00190 daq01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:daq00190 daq01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:daq00061 daq01212 daq01100]
M00083 Fatty acid biosynthesis, elongation [PATH:daq00061 daq01212 daq01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:daq00061 daq00071 daq01212 daq01100]
M00087 beta-Oxidation [PATH:daq00071 daq01212 daq01100]

Sterol biosynthesis
Lipid metabolism
M00098 Acylglycerol degradation [PATH:daq00561 daq01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:daq00564 daq01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:daq00230 daq01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:daq00230 daq01232 daq01240 daq01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:daq00230 daq01232 daq01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:daq00230 daq00240 daq01232 daq01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:daq00230 daq01232 daq01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:daq00230 daq01232 daq01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:daq00240 daq01240 daq01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:daq00240 daq01232 daq01240 daq01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:daq00240 daq01232 daq01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:daq00240 daq00410 daq00770 daq01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:daq00260 daq00680 daq01200 daq01230 daq01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:daq00260 daq01230 daq01100 daq01110]
M00621 Glycine cleavage system [PATH:daq00260 daq00630 daq00670 daq00785 daq01200 daq01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:daq00270 daq00920 daq01320 daq01200 daq01230 daq01100 daq01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:daq00260 daq00270 daq00670 daq01230 daq01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:daq00270 daq01230 daq01100]
M00034 Methionine salvage pathway [PATH:daq00270 daq01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:daq00290 daq00770 daq01210 daq01230 daq01100 daq01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:daq00290 daq01230 daq01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:daq00290 daq01210 daq01230 daq01100 daq01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:daq00300 daq01230 daq01100]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:daq00300 daq01210 daq01230 daq01100]
M00031 Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine [PATH:daq00300 daq01210 daq01230 daq01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:daq00220 daq01210 daq01230 daq01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:daq00220 daq01230 daq01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:daq00330 daq01230 daq01100]
M00970 Proline degradation, proline => glutamate [PATH:daq00330 daq01100]
M00972 Proline metabolism [PATH:daq00330 daq01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:daq00340 daq01230 daq01100 daq01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:daq00340 daq01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:daq00400 daq01230 daq01100 daq01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:daq00400 daq01230 daq01100 daq01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:daq00400 daq01230 daq01100 daq01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:daq00400 daq01230 daq01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:daq00480 daq01240 daq01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:daq00520 daq01250 daq01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:daq00520 daq01250 daq01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:daq00520 daq01250 daq01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:daq00520 daq00053 daq01250 daq01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:daq00520 daq00052 daq01250 daq01100]
M01009 UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc [PATH:daq00541]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:daq00541 daq01250 daq01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:daq00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:daq00541 daq01250 daq01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:daq00541 daq01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:daq00521 daq00523 daq00541 daq01250 daq01100 daq01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:daq00540 daq01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:daq00730 daq01240 daq01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:daq00740 daq01240 daq01100 daq01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:daq00750 daq01240 daq01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:daq00750 daq01240 daq01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:daq00760 daq01240 daq01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:daq00770 daq01240 daq01100 daq01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:daq00770 daq01240 daq01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:daq00780 daq01240 daq01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:daq00780 daq01240 daq01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:daq00785 daq01240 daq01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:daq00790 daq00670 daq01240 daq01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:daq00790 daq01240 daq01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:daq00790 daq01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:daq00860 daq01240 daq01100 daq01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:daq00860 daq01240 daq01100 daq01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:daq00860 daq01240 daq01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:daq00130 daq01240 daq01100 daq01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:daq00130 daq01240 daq01100 daq01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:daq00130 daq01240 daq01100 daq01110]
M00930 Menaquinone biosynthesis, futalosine pathway [PATH:daq00130 daq01240 daq01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:daq00900 daq01100 daq01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:daq00900 daq01100 daq01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
M00675 Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate [PATH:daq00332 daq01100 daq01110]

Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00649 Multidrug resistance, efflux pump AdeABC [PATH:daq01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity