KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:erwi00010 erwi01200 erwi01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:erwi00010 erwi01200 erwi01230 erwi01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:erwi00010 erwi00020 erwi01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:erwi00010 erwi00020 erwi00620 erwi00785 erwi01200 erwi01210 erwi01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:erwi00020 erwi01200 erwi01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:erwi00020 erwi01200 erwi01210 erwi01230 erwi01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:erwi00020 erwi01200 erwi01210 erwi01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:erwi00030 erwi01200 erwi01100 erwi01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:erwi00030 erwi01200 erwi01100 erwi01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:erwi00030 erwi01200 erwi01230 erwi01100 erwi01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:erwi00030 erwi00230 erwi01200 erwi01230 erwi01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:erwi00040 erwi00030 erwi01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:erwi00040 erwi00030 erwi01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:erwi00052 erwi01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:erwi00500 erwi01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:erwi00500 erwi01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:erwi00500 erwi01100 erwi01110]
M00012 Glyoxylate cycle [PATH:erwi00630 erwi01200 erwi01100 erwi01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:erwi00620 erwi00710 erwi01200 erwi01100 erwi01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:erwi00430 erwi00620 erwi00720 erwi01200 erwi01100 erwi01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:erwi00920 erwi01320 erwi01100 erwi01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:erwi00190 erwi01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:erwi00190 erwi01100]
M00150 Fumarate reductase, prokaryotes [PATH:erwi00190 erwi01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:erwi00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:erwi00190 erwi01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:erwi00190 erwi01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:erwi00061 erwi01212 erwi01100]
M00083 Fatty acid biosynthesis, elongation [PATH:erwi00061 erwi01212 erwi01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:erwi00061 erwi00071 erwi01212 erwi01100]
M00087 beta-Oxidation [PATH:erwi00071 erwi01212 erwi01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:erwi00564 erwi01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:erwi00230 erwi01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:erwi00230 erwi01232 erwi01240 erwi01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:erwi00230 erwi01232 erwi01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:erwi00230 erwi00240 erwi01232 erwi01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:erwi00240 erwi01240 erwi01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:erwi00240 erwi01232 erwi01240 erwi01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:erwi00240 erwi01232 erwi01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:erwi00240 erwi01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:erwi00260 erwi00680 erwi01200 erwi01230 erwi01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:erwi00260 erwi01230 erwi01100 erwi01110]
M00621 Glycine cleavage system [PATH:erwi00260 erwi00630 erwi00670 erwi00785 erwi01200 erwi01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:erwi00260 erwi00670 erwi01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:erwi00270 erwi00920 erwi01320 erwi01200 erwi01230 erwi01100 erwi01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:erwi00270 erwi01230 erwi01100]
M00034 Methionine salvage pathway [PATH:erwi00270 erwi01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:erwi00290 erwi00770 erwi01210 erwi01230 erwi01100 erwi01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:erwi00290 erwi01230 erwi01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:erwi00290 erwi01210 erwi01230 erwi01100 erwi01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:erwi00300 erwi01230 erwi01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:erwi00220 erwi01210 erwi01230 erwi01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:erwi00220 erwi01230 erwi01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:erwi00330 erwi01230 erwi01100]
M00970 Proline degradation, proline => glutamate [PATH:erwi00330 erwi01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:erwi00330 erwi01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:erwi00330 erwi01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:erwi00330 erwi01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:erwi00340 erwi01230 erwi01100 erwi01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:erwi00340 erwi01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:erwi00400 erwi01230 erwi01100 erwi01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:erwi00400 erwi01230 erwi01100 erwi01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:erwi00400 erwi01230 erwi01100 erwi01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:erwi00400 erwi01230 erwi01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:erwi00480 erwi01240 erwi01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:erwi00520 erwi01250 erwi01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:erwi00520 erwi01250 erwi01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:erwi00520 erwi01250 erwi01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:erwi00520 erwi00053 erwi01250 erwi01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:erwi00520 erwi00052 erwi01250 erwi01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:erwi00541 erwi01250 erwi01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:erwi00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:erwi00541 erwi01250 erwi01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:erwi00541 erwi01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:erwi00540 erwi01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:erwi00730 erwi01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:erwi00740 erwi01240 erwi01100 erwi01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:erwi00750 erwi01240 erwi01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:erwi00760 erwi01240 erwi01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:erwi00770 erwi01240 erwi01100 erwi01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:erwi00770 erwi01240 erwi01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:erwi00780 erwi01240 erwi01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:erwi00785 erwi01240 erwi01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:erwi00790 erwi00670 erwi01240 erwi01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:erwi00790 erwi01240 erwi01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:erwi00790 erwi01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:erwi00860 erwi01240 erwi01100 erwi01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:erwi00860 erwi01240 erwi01100 erwi01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:erwi00130 erwi01240 erwi01100 erwi01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:erwi00130 erwi01240 erwi01100 erwi01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:erwi00130 erwi01240 erwi01100 erwi01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:erwi00900 erwi01100 erwi01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:erwi00900 erwi01100 erwi01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation