KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:hahe00010 hahe01200 hahe01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:hahe00010 hahe01200 hahe01230 hahe01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:hahe00010 hahe00020 hahe01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:hahe00010 hahe00020 hahe00620 hahe00785 hahe01200 hahe01210 hahe01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:hahe00020 hahe01200 hahe01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:hahe00020 hahe01200 hahe01210 hahe01230 hahe01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:hahe00020 hahe01200 hahe01210 hahe01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:hahe00030 hahe01200 hahe01230 hahe01100 hahe01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:hahe00030 hahe00230 hahe01200 hahe01230 hahe01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:hahe00030 hahe01200 hahe01100 hahe01120]

Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH:hahe00630 hahe01200 hahe01100 hahe01110]
M00982 Methylcitrate cycle [PATH:hahe00640 hahe00020 hahe01200 hahe01100 hahe01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:hahe00620 hahe00710 hahe01200 hahe01100 hahe01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:hahe00430 hahe00620 hahe00720 hahe01200 hahe01100 hahe01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:hahe00910 hahe01310 hahe01100 hahe01120]

Sulfur metabolism
Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:hahe00190 hahe01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:hahe00190 hahe01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:hahe00190 hahe01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:hahe00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:hahe00190 hahe01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:hahe00190 hahe01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:hahe00061 hahe01212 hahe01100]
M00083 Fatty acid biosynthesis, elongation [PATH:hahe00061 hahe01212 hahe01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:hahe00061 hahe00071 hahe01212 hahe01100]
M00087 beta-Oxidation [PATH:hahe00071 hahe01212 hahe01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:hahe00564 hahe01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hahe00230 hahe01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hahe00230 hahe01232 hahe01240 hahe01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hahe00230 hahe01232 hahe01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hahe00230 hahe00240 hahe01232 hahe01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:hahe00230 hahe01232 hahe01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:hahe00230 hahe01232 hahe01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:hahe00240 hahe01232 hahe01240 hahe01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:hahe00240 hahe01232 hahe01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:hahe00260 hahe00680 hahe01200 hahe01230 hahe01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:hahe00260 hahe01230 hahe01100 hahe01110]
M00621 Glycine cleavage system [PATH:hahe00260 hahe00630 hahe00670 hahe00785 hahe01200 hahe01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:hahe00260 hahe00670 hahe01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:hahe00260 hahe01210 hahe01230 hahe01100 hahe01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:hahe00270 hahe00920 hahe01320 hahe01200 hahe01230 hahe01100 hahe01110]
M00035 Methionine degradation [PATH:hahe00270 hahe00670 hahe01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:hahe00290 hahe00770 hahe01210 hahe01230 hahe01100 hahe01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:hahe00290 hahe01230 hahe01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:hahe00290 hahe01210 hahe01230 hahe01100 hahe01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:hahe00280 hahe01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:hahe00300 hahe01230 hahe01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:hahe00220 hahe01210 hahe01230 hahe01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:hahe00220 hahe01230 hahe01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:hahe00330 hahe01230 hahe01100]
M00970 Proline degradation, proline => glutamate [PATH:hahe00330 hahe01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:hahe00330 hahe01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:hahe00330 hahe01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:hahe00340 hahe01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:hahe00400 hahe01230 hahe01100 hahe01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:hahe00400 hahe01230 hahe01100 hahe01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:hahe00480 hahe01240 hahe01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:hahe00520 hahe01250 hahe01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:hahe00520 hahe01250]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:hahe00520 hahe01250]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:hahe00520 hahe01250 hahe01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:hahe00520 hahe00053 hahe01250]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:hahe00520 hahe01250]
M01009 UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc [PATH:hahe00541]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:hahe00541 hahe01250 hahe01100]
M01028 GDP-DDmanHep biosynthesis, sedoheptulose-7P => GDP-DDmanHep [PATH:hahe00541]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:hahe00750 hahe01240 hahe01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:hahe00760 hahe01240 hahe01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:hahe00770 hahe01240 hahe01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:hahe00780 hahe01240 hahe01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:hahe00780 hahe01240 hahe01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:hahe00785 hahe01240 hahe01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:hahe00790 hahe00670 hahe01240 hahe01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:hahe00790 hahe01240 hahe01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:hahe00860 hahe01240 hahe01100 hahe01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:hahe00860 hahe01240 hahe01100 hahe01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:hahe00860 hahe01240 hahe01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:hahe00860 hahe01240 hahe01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00837 Prodigiosin biosynthesis, L-proline => prodigiosin [PATH:hahe00333 hahe01100 hahe01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation