KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:mbo00010 mbo01200 mbo01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:mbo00010 mbo01200 mbo01230 mbo01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:mbo00010 mbo00020 mbo01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:mbo00010 mbo00020 mbo00620 mbo00785 mbo01200 mbo01210 mbo01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:mbo00020 mbo01200 mbo01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:mbo00020 mbo01200 mbo01210 mbo01230 mbo01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:mbo00020 mbo01200 mbo01210 mbo01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:mbo00030 mbo01200 mbo01100 mbo01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:mbo00030 mbo01200 mbo01100 mbo01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:mbo00030 mbo01200 mbo01230 mbo01100 mbo01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:mbo00030 mbo00230 mbo01200 mbo01230 mbo01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:mbo00052 mbo01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:mbo00500 mbo01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:mbo00520 mbo01250 mbo01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:mbo00520 mbo00052 mbo01250 mbo01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:mbo00520 mbo01250 mbo01100]
M00012 Glyoxylate cycle [PATH:mbo00630 mbo01200 mbo01100 mbo01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mbo00280 mbo00630 mbo00640 mbo01200 mbo01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:mbo00620 mbo00710 mbo01200 mbo01100 mbo01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:mbo00430 mbo00620 mbo00720 mbo01200 mbo01100 mbo01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:mbo00910 mbo01100 mbo01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:mbo00920 mbo01100 mbo01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:mbo00190 mbo01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:mbo00190 mbo01100]
M00150 Fumarate reductase, prokaryotes [PATH:mbo00190 mbo01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:mbo00190 mbo01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:mbo00190 mbo01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:mbo00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:mbo00190 mbo01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:mbo00190 mbo01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:mbo00061 mbo01212 mbo01100]
M00083 Fatty acid biosynthesis, elongation [PATH:mbo00061 mbo01212 mbo01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:mbo00061 mbo00071 mbo01212 mbo01100]
M00087 beta-Oxidation [PATH:mbo00071 mbo01212 mbo01100]

Sterol biosynthesis
Lipid metabolism
M00098 Acylglycerol degradation [PATH:mbo00561 mbo01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:mbo00564 mbo01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mbo00230 mbo01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mbo00230 mbo01232 mbo01240 mbo01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mbo00230 mbo01232 mbo01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mbo00230 mbo00240 mbo01232 mbo01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:mbo00230 mbo01232 mbo01100]
M00546 Purine degradation, xanthine => urea [PATH:mbo00230 mbo01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:mbo00240 mbo01232 mbo01240 mbo01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:mbo00240 mbo01232 mbo01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:mbo00260 mbo00680 mbo01200 mbo01230 mbo01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:mbo00260 mbo01230 mbo01100 mbo01110]
M00621 Glycine cleavage system [PATH:mbo00260 mbo00630 mbo00785 mbo01200 mbo01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:mbo00260 mbo01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:mbo00260 mbo01210 mbo01230 mbo01100 mbo01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:mbo00270 mbo00920 mbo01200 mbo01230 mbo01100 mbo01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:mbo00260 mbo00270 mbo01230 mbo01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:mbo00270 mbo01230 mbo01100]
M00034 Methionine salvage pathway [PATH:mbo00270 mbo01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:mbo00290 mbo00770 mbo01210 mbo01230 mbo01100 mbo01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:mbo00290 mbo01230 mbo01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:mbo00290 mbo01210 mbo01230 mbo01100 mbo01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:mbo00300 mbo01230 mbo01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:mbo00220 mbo01210 mbo01230 mbo01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:mbo00220 mbo01230 mbo01100]
M00978 Ornithine-ammonia cycle [PATH:mbo00220]
M00015 Proline biosynthesis, glutamate => proline [PATH:mbo00330 mbo01230 mbo01100]
M00970 Proline degradation, proline => glutamate [PATH:mbo00330 mbo01100]
M00972 Proline metabolism [PATH:mbo00330 mbo01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:mbo00330 mbo01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:mbo00340 mbo01230 mbo01100 mbo01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:mbo00340 mbo01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:mbo00400 mbo01230 mbo01100 mbo01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:mbo00400 mbo01230 mbo01100 mbo01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:mbo00400 mbo01230 mbo01100 mbo01110]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:mbo00250 mbo00650 mbo01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:mbo00480 mbo01240 mbo01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:mbo00540 mbo01100]
M00063 CMP-KDO biosynthesis [PATH:mbo00540 mbo01250 mbo01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:mbo00540 mbo01250 mbo01100]
M00922 CMP-Neu5Ac biosynthesis [PATH:mbo00541 mbo01250 mbo01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:mbo00730 mbo01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:mbo00740 mbo01240 mbo01100 mbo01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:mbo00750 mbo01240 mbo01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:mbo00760 mbo01240 mbo01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:mbo00770 mbo01240 mbo01100 mbo01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:mbo00770 mbo01240 mbo01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:mbo00780 mbo01240 mbo01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:mbo00785 mbo01240 mbo01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:mbo00785 mbo01240 mbo01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:mbo00790 mbo00670 mbo01240 mbo01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:mbo00790 mbo01240 mbo01100]
M00140 C1-unit interconversion, prokaryotes [PATH:mbo00670 mbo01240 mbo01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:mbo00860 mbo01240 mbo01100 mbo01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:mbo00860 mbo01240 mbo01100 mbo01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:mbo00860 mbo01240 mbo01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:mbo00860 mbo01240 mbo01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:mbo00130 mbo01240 mbo01100 mbo01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:mbo00130 mbo01240 mbo01100 mbo01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:mbo00900 mbo01100 mbo01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:mbo00900 mbo01100 mbo01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:mbo00521 mbo00523 mbo00541 mbo01250 mbo01100 mbo01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:mbo00360 mbo01220 mbo01100 mbo01120]

Gene set
Pathogenicity
Drug resistance
M00625 Methicillin resistance [PATH:mbo01501]
M00627 beta-Lactam resistance, Bla system [PATH:mbo01501]
M00700 Multidrug resistance, efflux pump AbcA
M00702 Multidrug resistance, efflux pump NorB
M00705 Multidrug resistance, efflux pump MepA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation