KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:paer00010 paer01200 paer01230 paer01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:paer00010 paer00020 paer01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:paer00010 paer00020 paer00620 paer01200 paer01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:paer00020 paer01200 paer01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:paer00020 paer01200 paer01210 paer01230 paer01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:paer00020 paer01200 paer01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:paer00030 paer01200 paer01230 paer01100 paer01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:paer00030 paer00230 paer01200 paer01230 paer01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:paer00030 paer01200 paer01100 paer01120]

Other carbohydrate metabolism
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:paer00520 paer01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:paer00520 paer01100]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:paer00430 paer00620 paer01200 paer01100 paer01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:paer00910 paer01100 paer01120]
M00529 Denitrification, nitrate => nitrogen [PATH:paer00910 paer01100 paer01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:paer00920 paer01100 paer01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:paer00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH:paer00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:paer00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:paer00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:paer00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:paer00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:paer00061 paer01212 paer01100]
M00083 Fatty acid biosynthesis, elongation [PATH:paer00061 paer01212 paer01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:paer00061 paer00071 paer01212 paer01100]
M00087 beta-Oxidation [PATH:paer00071 paer01212 paer01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:paer00564 paer01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:paer00230 paer01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:paer00230 paer01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:paer00230 paer01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:paer00240 paer01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH:paer00240 paer01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:paer00240 paer01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:paer00260 paer00680 paer01200 paer01230 paer01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:paer00260 paer01230 paer01100 paer01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:paer00260 paer01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:paer00270 paer00920 paer01200 paer01230 paer01100 paer01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:paer00260 paer00270 paer01230 paer01100]
M00035 Methionine degradation [PATH:paer00270 paer01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:paer00290 paer00770 paer01210 paer01230 paer01100 paer01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:paer00290 paer01230 paer01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:paer00290 paer01210 paer01230 paer01100 paer01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:paer00300 paer01230 paer01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:paer00220 paer01210 paer01230 paer01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:paer00220 paer01230 paer01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:paer00330 paer01230 paer01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:paer00330 paer01100]

Polyamine biosynthesis
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:paer00330 paer01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:paer00340 paer01230 paer01100 paer01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:paer00340 paer01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:paer00400 paer01230 paer01100 paer01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:paer00400 paer01230 paer01100 paer01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:paer00400 paer01230 paer01100 paer01110]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:paer00400 paer01230 paer01100 paer01110]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:paer00350 paer01220 paer01100 paer01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:paer00480 paer01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:paer00540 paer01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:paer00540 paer01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:paer00740 paer01100 paer01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:paer00750 paer01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:paer00760 paer01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:paer00770 paer01100 paer01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:paer00770 paer01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:paer00780 paer01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:paer00780 paer01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:paer00790 paer00670 paer01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:paer00790 paer01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:paer00860 paer01100 paer01110]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:paer00860 paer01100 paer01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:paer00860 paer01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:paer00521 paer00523 paer00541 paer01100 paer01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00835 Pyocyanine biosynthesis, chorismate => pyocyanine [PATH:paer00405 paer01100 paer01110]

Xenobiotics biodegradation
Aromatics degradation
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:paer00362 paer00622 paer01220 paer01100 paer01120]
M00637 Anthranilate degradation, anthranilate => catechol [PATH:paer00627 paer01100 paer01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:paer00362 paer01220 paer01100 paer01120]

Gene set
Pathogenicity
Drug resistance
M00745 Imipenem resistance, repression of porin OprD
M00718 Multidrug resistance, efflux pump MexAB-OprM
M00639 Multidrug resistance, efflux pump MexCD-OprJ
M00641 Multidrug resistance, efflux pump MexEF-OprN
M00642 Multidrug resistance, efflux pump MexJK-OprM

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation