KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:pagc00010 pagc01200 pagc01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:pagc00010 pagc01200 pagc01230 pagc01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:pagc00010 pagc00020 pagc01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:pagc00010 pagc00020 pagc00620 pagc00785 pagc01200 pagc01210 pagc01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:pagc00020 pagc01200 pagc01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pagc00020 pagc01200 pagc01210 pagc01230 pagc01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:pagc00020 pagc01200 pagc01210 pagc01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:pagc00030 pagc01200 pagc01100 pagc01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:pagc00030 pagc00230 pagc01200 pagc01230 pagc01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:pagc00040 pagc00030 pagc01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:pagc00040 pagc00030 pagc01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:pagc00052 pagc01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:pagc00500 pagc01100]
M00012 Glyoxylate cycle [PATH:pagc00630 pagc01200 pagc01100 pagc01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:pagc00620 pagc00710 pagc01200 pagc01100 pagc01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:pagc00430 pagc00620 pagc00720 pagc01200 pagc01100 pagc01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:pagc00910 pagc01310 pagc01100 pagc01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:pagc00910 pagc01310 pagc01100 pagc01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:pagc00920 pagc01320 pagc01100 pagc01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:pagc00190 pagc01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:pagc00190 pagc01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:pagc00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:pagc00190 pagc01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:pagc00190 pagc01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:pagc00061 pagc01212 pagc01100]
M00083 Fatty acid biosynthesis, elongation [PATH:pagc00061 pagc01212 pagc01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:pagc00061 pagc00071 pagc01212 pagc01100]
M00087 beta-Oxidation [PATH:pagc00071 pagc01212 pagc01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pagc00564 pagc01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pagc00230 pagc01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pagc00230 pagc01232 pagc01240 pagc01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pagc00230 pagc00240 pagc01232 pagc01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:pagc00240 pagc01240 pagc01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:pagc00240 pagc01232 pagc01240 pagc01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:pagc00240 pagc01232 pagc01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:pagc00240 pagc01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:pagc00260 pagc00680 pagc01200 pagc01230 pagc01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pagc00260 pagc01230 pagc01100 pagc01110]
M00621 Glycine cleavage system [PATH:pagc00260 pagc00630 pagc00670 pagc00785 pagc01200 pagc01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:pagc00260 pagc00670 pagc01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:pagc00270 pagc00920 pagc01320 pagc01200 pagc01230 pagc01100 pagc01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:pagc00270 pagc01230 pagc01100]
M00034 Methionine salvage pathway [PATH:pagc00270 pagc01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pagc00290 pagc00770 pagc01210 pagc01230 pagc01100 pagc01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pagc00290 pagc01230 pagc01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pagc00290 pagc01210 pagc01230 pagc01100 pagc01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:pagc00300 pagc01230 pagc01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:pagc00220 pagc01210 pagc01230 pagc01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:pagc00220 pagc01230 pagc01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:pagc00330 pagc01230 pagc01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:pagc00330 pagc01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:pagc00330 pagc01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:pagc00340 pagc01230 pagc01100 pagc01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:pagc00340 pagc01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pagc00400 pagc01230 pagc01100 pagc01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:pagc00400 pagc01230 pagc01100 pagc01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:pagc00400 pagc01230 pagc01100 pagc01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:pagc00400 pagc01230 pagc01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:pagc00480 pagc01240 pagc01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:pagc00520 pagc01250 pagc01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:pagc00520 pagc01250 pagc01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:pagc00520 pagc01250 pagc01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:pagc00520 pagc00053 pagc01250 pagc01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:pagc00520 pagc00052 pagc01250 pagc01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:pagc00541 pagc01250 pagc01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:pagc00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:pagc00541 pagc01250 pagc01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:pagc00541 pagc01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:pagc00521 pagc00523 pagc00541 pagc01250 pagc01100 pagc01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:pagc00730 pagc01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:pagc00760 pagc01240 pagc01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:pagc00770 pagc01240 pagc01100 pagc01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:pagc00770 pagc01240 pagc01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:pagc00780 pagc01240 pagc01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:pagc00780 pagc01240 pagc01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:pagc00785 pagc01240 pagc01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:pagc00790 pagc00670 pagc01240 pagc01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pagc00790 pagc01240 pagc01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:pagc00790 pagc01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:pagc00860 pagc01240 pagc01100 pagc01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:pagc00860 pagc01240 pagc01100 pagc01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pagc00130 pagc01240 pagc01100 pagc01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pagc00130 pagc01240 pagc01100 pagc01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:pagc00900 pagc01100 pagc01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:pagc00900 pagc01100 pagc01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
M00904 Dapdiamides biosynthesis, L-2,3-diaminopropanoate => dapdiamide A/B/C [PATH:pagc00998 pagc01100 pagc01110]

Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation