KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:pea00010 pea01200 pea01230 pea01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:pea00010 pea00020 pea01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:pea00010 pea00020 pea00620 pea01200 pea01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:pea00020 pea01200 pea01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pea00020 pea01200 pea01210 pea01230 pea01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:pea00020 pea01200 pea01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:pea00030 pea01200 pea01100 pea01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:pea00030 pea01200 pea01100 pea01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:pea00030 pea01200 pea01230 pea01100 pea01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:pea00030 pea00230 pea01200 pea01230 pea01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:pea00030 pea01200 pea01100 pea01120]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:pea00052 pea01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:pea00500 pea01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:pea00520 pea01250 pea01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:pea00520 pea00052 pea01250 pea01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:pea00520 pea01250 pea01100]
M00012 Glyoxylate cycle [PATH:pea00630 pea01200 pea01100 pea01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:pea00620 pea01200 pea01100 pea01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:pea00430 pea00620 pea01200 pea01100 pea01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:pea00920 pea01100 pea01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:pea00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:pea00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:pea00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:pea00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:pea00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:pea00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:pea00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:pea00061 pea01212 pea01100]
M00083 Fatty acid biosynthesis, elongation [PATH:pea00061 pea01212 pea01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:pea00061 pea00071 pea01212 pea01100]
M00087 beta-Oxidation [PATH:pea00071 pea01212 pea01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pea00564 pea01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pea00230 pea01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pea00230 pea01232 pea01240 pea01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pea00230 pea01232 pea01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pea00230 pea00240 pea01232 pea01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:pea00230 pea01232]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:pea00230 pea01232]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:pea00240 pea01232 pea01240 pea01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:pea00240 pea01232 pea01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:pea00260 pea00680 pea01200 pea01230 pea01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pea00260 pea01230 pea01100 pea01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:pea00260 pea01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:pea00270 pea00920 pea01200 pea01230 pea01100 pea01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:pea00270 pea01230 pea01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pea00290 pea00770 pea01210 pea01230 pea01100 pea01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pea00290 pea01230 pea01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pea00290 pea01210 pea01230 pea01100 pea01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:pea00280 pea01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:pea00300 pea01230 pea01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:pea00220 pea01210 pea01230 pea01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:pea00220 pea01230 pea01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:pea00330 pea01230 pea01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:pea00330 pea01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:pea00340 pea01230 pea01100 pea01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:pea00340 pea01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pea00400 pea01230 pea01100 pea01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:pea00400 pea01230 pea01100 pea01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:pea00480 pea01240 pea01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:pea00540 pea01250 pea01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:pea00740 pea01240 pea01100 pea01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:pea00750 pea01240 pea01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:pea00760 pea01240 pea01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:pea00770 pea01240 pea01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:pea00780 pea01240 pea01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:pea00785 pea01240 pea01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:pea00790 pea00670 pea01240 pea01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pea00790 pea01240 pea01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:pea00860 pea01240 pea01100 pea01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:pea00860 pea01240 pea01100 pea01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pea00130 pea01240 pea01100 pea01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity