KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:pmav00010 pmav01200 pmav01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:pmav00010 pmav01200 pmav01230 pmav01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:pmav00010 pmav00020 pmav01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:pmav00010 pmav00020 pmav00620 pmav00785 pmav01200 pmav01210 pmav01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:pmav00020 pmav01200 pmav01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pmav00020 pmav01200 pmav01210 pmav01230 pmav01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:pmav00020 pmav01200 pmav01210 pmav01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:pmav00030 pmav01200 pmav01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:pmav00030 pmav01200 pmav01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:pmav00030 pmav01200 pmav01230 pmav01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:pmav00030 pmav00230 pmav01200 pmav01230 pmav01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:pmav00040 pmav01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:pmav00052 pmav01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:pmav00040 pmav00053 pmav01240 pmav01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:pmav00500 pmav01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:pmav00500 pmav01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:pmav00280 pmav00630 pmav00640 pmav01200 pmav01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:pmav00562 pmav01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:pmav00562 pmav01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:pmav00562 pmav01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00148 Succinate dehydrogenase (ubiquinone) [PATH:pmav00190 pmav01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:pmav00190 pmav01100]
M00154 Cytochrome c oxidase [PATH:pmav00190 pmav01100]
M00160 V-type ATPase, eukaryotes [PATH:pmav00190 pmav01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:pmav00061 pmav01212 pmav01100]
M00083 Fatty acid biosynthesis, elongation [PATH:pmav00061 pmav01212 pmav01100]
M00873 Fatty acid biosynthesis in mitochondria, animals [PATH:pmav00061 pmav01212 pmav01100]
M00085 Fatty acid elongation in mitochondria [PATH:pmav00062 pmav01212 pmav01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:pmav00062 pmav01040 pmav01212 pmav01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:pmav00061 pmav00071 pmav01212 pmav01100]
M00087 beta-Oxidation [PATH:pmav00071 pmav01212 pmav01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:pmav01040 pmav01212 pmav01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH:pmav00100 pmav01100]
M00103 Cholecalciferol biosynthesis [PATH:pmav00100 pmav01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH:pmav00120 pmav01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:pmav00120 pmav01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:pmav00140 pmav01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:pmav00561 pmav01100]
M00098 Acylglycerol degradation [PATH:pmav00561 pmav01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pmav00564 pmav01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pmav00564 pmav01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pmav00564 pmav01100]
M00094 Ceramide biosynthesis [PATH:pmav00600 pmav01100]
M00066 Lactosylceramide biosynthesis [PATH:pmav00600 pmav01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:pmav00600 pmav00565 pmav01100]
M00099 Sphingosine biosynthesis [PATH:pmav00600 pmav01100]
M00100 Sphingosine degradation [PATH:pmav00600 pmav01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pmav00230 pmav01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pmav00230 pmav01232 pmav01240 pmav01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pmav00230 pmav01232 pmav01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pmav00230 pmav00240 pmav01232 pmav01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:pmav00230 pmav01232 pmav01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:pmav00230 pmav01232 pmav01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:pmav00240 pmav01240 pmav01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:pmav00240 pmav01232 pmav01240 pmav01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:pmav00240 pmav00410 pmav00770 pmav01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:pmav00260 pmav01200 pmav01230 pmav01100]
M00621 Glycine cleavage system [PATH:pmav00260 pmav00630 pmav00670 pmav00785 pmav01200 pmav01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:pmav00260 pmav00670 pmav01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:pmav00260 pmav00670 pmav01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:pmav00260 pmav00270 pmav00670 pmav01230 pmav01100]
M00034 Methionine salvage pathway [PATH:pmav00270 pmav01100]
M00035 Methionine degradation [PATH:pmav00270 pmav00670 pmav01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:pmav00280 pmav01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:pmav00310 pmav01210 pmav01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:pmav00220 pmav01230 pmav01100]
M00029 Urea cycle [PATH:pmav00220 pmav01230 pmav01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:pmav00330 pmav01230 pmav01100]
M00970 Proline degradation, proline => glutamate [PATH:pmav00330 pmav01100]
M00972 Proline metabolism [PATH:pmav00330 pmav01100]
M00047 Creatine pathway [PATH:pmav00330 pmav00260 pmav01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:pmav00330 pmav01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:pmav00330 pmav01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:pmav00340 pmav01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:pmav00350 pmav01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:pmav00350 pmav01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:pmav00350 pmav01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:pmav00380 pmav01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:pmav00250 pmav00650 pmav01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:pmav00480 pmav01240 pmav01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH:pmav00520 pmav01250 pmav01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH:pmav00520 pmav01250 pmav01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:pmav00520 pmav01250 pmav01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:pmav00520 pmav00052 pmav01250 pmav01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:pmav00520 pmav00051 pmav01250 pmav01100]
M01015 GDP-Man biosynthesis, Man => GDP-Man [PATH:pmav00520 pmav00051 pmav01100]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH:pmav00520 pmav01250 pmav01100]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH:pmav00541 pmav01250 pmav01100]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:pmav00541 pmav00051 pmav01250 pmav01100]

Glycan biosynthesis
M00072 N-glycosylation by oligosaccharyltransferase [PATH:pmav00510 pmav00513 pmav01100]
M00073 N-glycan precursor trimming [PATH:pmav00510 pmav01100]
M00075 N-glycan biosynthesis, complex type [PATH:pmav00510 pmav01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:pmav00515 pmav01100]
M00983 GPI-anchor remodeling [PATH:pmav00563 pmav01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:pmav00601 pmav01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:pmav00601 pmav01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:pmav00603 pmav01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:pmav00604 pmav01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:pmav00532 pmav00534 pmav01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:pmav00532 pmav01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:pmav00534 pmav01100]
M00076 Dermatan sulfate degradation [PATH:pmav00531 pmav01100]
M00077 Chondroitin sulfate degradation [PATH:pmav00531 pmav01100]
M00079 Keratan sulfate degradation [PATH:pmav00531 pmav01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:pmav00380 pmav00760 pmav01240 pmav01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:pmav00770 pmav01240 pmav01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:pmav00785 pmav01240 pmav01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:pmav00785 pmav01240 pmav01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pmav00790 pmav01240 pmav01100]
M00141 C1-unit interconversion, eukaryotes [PATH:pmav00670 pmav01240 pmav01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:pmav00860 pmav01240 pmav01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:pmav00900 pmav01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity