KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:prh00010 prh01200 prh01230 prh01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:prh00010 prh00020 prh01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:prh00010 prh00020 prh00620 prh01200 prh01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:prh00020 prh01200 prh01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:prh00020 prh01200 prh01210 prh01230 prh01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:prh00020 prh01200 prh01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:prh00030 prh01200 prh01100 prh01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:prh00030 prh01200 prh01100 prh01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:prh00030 prh01200 prh01230 prh01100 prh01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:prh00030 prh00230 prh01200 prh01230 prh01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:prh00030 prh01200 prh01100 prh01120]

Other carbohydrate metabolism
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:prh00052 prh01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:prh00520 prh01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:prh00520 prh01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:prh00920 prh01100 prh01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:prh00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH:prh00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:prh00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:prh00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:prh00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:prh00061 prh01212 prh01100]
M00083 Fatty acid biosynthesis, elongation [PATH:prh00061 prh01212 prh01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:prh00061 prh00071 prh01212 prh01100]
M00087 beta-Oxidation [PATH:prh00071 prh01212 prh01100]

Sterol biosynthesis
Lipid metabolism
Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:prh00230 prh01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:prh00230 prh01240 prh01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:prh00230 prh01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:prh00240 prh01240 prh01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP => dCTP [PATH:prh00240]
M00938 Pyrimidine deoxyribonuleotide biosynthesis, UDP => dTTP [PATH:prh00240]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:prh00260 prh00680 prh01200 prh01230 prh01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:prh00260 prh01230 prh01100 prh01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:prh00260 prh01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:prh00270 prh00920 prh01200 prh01230 prh01100 prh01110]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:prh00290 prh00770 prh01210 prh01230 prh01100 prh01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:prh00290 prh01230 prh01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:prh00290 prh01210 prh01230 prh01100 prh01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:prh00280 prh01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:prh00300 prh01230 prh01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:prh00220 prh01210 prh01230 prh01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:prh00220 prh01230 prh01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:prh00330 prh01230 prh01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:prh00330 prh01100]

Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:prh00400 prh01230 prh01100 prh01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:prh00400 prh01230 prh01100 prh01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:prh00400 prh01230 prh01100 prh01110]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:prh00400 prh01230 prh01100 prh01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:prh00480 prh01240 prh01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:prh00540 prh01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:prh00740 prh01240 prh01100 prh01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:prh00750 prh01240 prh01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:prh00760 prh01240 prh01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:prh00780 prh01240 prh01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:prh00780 prh01240 prh01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:prh00785 prh01240 prh01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:prh00790 prh01240 prh01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:prh00860 prh01240 prh01100 prh01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:prh00860 prh01240 prh01100 prh01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:prh00860 prh01240 prh01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:prh00900 prh01100 prh01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:prh00900 prh01100 prh01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:prh00521 prh00523 prh00541 prh01100 prh01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00745 Imipenem resistance, repression of porin OprD
M00641 Multidrug resistance, efflux pump MexEF-OprN

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation