KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:prr00010 prr01200 prr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:prr00010 prr01200 prr01230 prr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:prr00010 prr00020 prr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:prr00010 prr00020 prr00620 prr01200 prr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:prr00020 prr01200 prr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:prr00020 prr01200 prr01210 prr01230 prr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:prr00020 prr01200 prr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:prr00030 prr01200 prr01100 prr01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:prr00030 prr01200 prr01100 prr01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:prr00030 prr01200 prr01230 prr01100 prr01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:prr00030 prr00230 prr01200 prr01230 prr01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:prr00030 prr01200 prr01100 prr01120]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:prr00500 prr01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:prr00520 prr01250 prr01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:prr00520 prr01250 prr01100]
M00012 Glyoxylate cycle [PATH:prr00630 prr01200 prr01100 prr01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:prr00620 prr01200 prr01100 prr01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:prr00430 prr00620 prr01200 prr01100 prr01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:prr00920 prr01100 prr01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:prr00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:prr00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:prr00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:prr00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:prr00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:prr00061 prr01212 prr01100]
M00083 Fatty acid biosynthesis, elongation [PATH:prr00061 prr01212 prr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:prr00061 prr00071 prr01212 prr01100]
M00087 beta-Oxidation [PATH:prr00071 prr01212 prr01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:prr00564 prr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:prr00230 prr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:prr00230 prr01232 prr01240 prr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:prr00230 prr01232 prr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:prr00230 prr00240 prr01232 prr01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:prr00240 prr01232 prr01240 prr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:prr00260 prr00680 prr01200 prr01230 prr01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:prr00260 prr01230 prr01100 prr01110]
M00621 Glycine cleavage system [PATH:prr00260 prr00630 prr01200 prr01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:prr00260 prr01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:prr00270 prr00920 prr01200 prr01230 prr01100 prr01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:prr00270 prr01230 prr01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:prr00290 prr00770 prr01210 prr01230 prr01100 prr01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:prr00290 prr01230 prr01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:prr00290 prr01210 prr01230 prr01100 prr01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:prr00280 prr01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:prr00300 prr01230 prr01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:prr00220 prr01210 prr01230 prr01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:prr00220 prr01230 prr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:prr00330 prr01230 prr01100]
M00970 Proline degradation, proline => glutamate [PATH:prr00330 prr01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:prr00330 prr01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:prr00340 prr01230 prr01100 prr01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:prr00340 prr01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:prr00400 prr01230 prr01100 prr01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:prr00400 prr01230 prr01100 prr01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:prr00480 prr01240 prr01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:prr00470 prr01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:prr00540 prr01250 prr01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:prr00740 prr01240 prr01100 prr01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:prr00750 prr01240 prr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:prr00760 prr01240 prr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:prr00770 prr01240 prr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:prr00780 prr01240 prr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:prr00785 prr01240 prr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:prr00790 prr00670 prr01240 prr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:prr00790 prr01240 prr01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:prr00860 prr01240 prr01100 prr01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:prr00860 prr01240 prr01100 prr01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:prr00860 prr01240 prr01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:prr00130 prr01240 prr01100 prr01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00837 Prodigiosin biosynthesis, L-proline => prodigiosin [PATH:prr00333 prr01100 prr01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00641 Multidrug resistance, efflux pump MexEF-OprN

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity