KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:reu00010 reu01200 reu01230 reu01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:reu00010 reu00020 reu01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:reu00010 reu00020 reu00620 reu00785 reu01200 reu01210 reu01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:reu00020 reu01200 reu01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:reu00020 reu01200 reu01210 reu01230 reu01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:reu00020 reu01200 reu01210 reu01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:reu00030 reu01200 reu01230 reu01100 reu01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:reu00030 reu00230 reu01200 reu01230 reu01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:reu00030 reu01200 reu01100 reu01120]

Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH:reu00630 reu01200 reu01100 reu01110]
M00982 Methylcitrate cycle [PATH:reu00640 reu00020 reu01200 reu01100 reu01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:reu00620 reu00710 reu01200 reu01100 reu01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:reu00430 reu00620 reu00720 reu01200 reu01100 reu01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:reu00910 reu01310 reu01100 reu01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:reu00920 reu01320 reu01100 reu01120]
M00595 Sulfur oxidation, SOX system, thiosulfate => sulfate [PATH:reu00920 reu01320 reu01100 reu01120]
M00985 Sulfide oxidation, sulfide => sulfur [PATH:reu00920 reu01320 reu01100 reu01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:reu00190 reu01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:reu00190 reu01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:reu00190 reu01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:reu00190 reu01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:reu00190 reu01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:reu00190 reu01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:reu00190 reu01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:reu00061 reu01212 reu01100]
M00083 Fatty acid biosynthesis, elongation [PATH:reu00061 reu01212 reu01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:reu00061 reu00071 reu01212 reu01100]
M00087 beta-Oxidation [PATH:reu00071 reu01212 reu01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:reu00564 reu01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:reu00230 reu01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:reu00230 reu01232 reu01240 reu01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:reu00230 reu01232 reu01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:reu00230 reu00240 reu01232 reu01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:reu00230 reu01232 reu01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:reu00230 reu01232 reu01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:reu00240 reu01232 reu01240 reu01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:reu00240 reu01232 reu01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:reu00260 reu00680 reu01200 reu01230 reu01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:reu00260 reu01230 reu01100 reu01110]
M00621 Glycine cleavage system [PATH:reu00260 reu00630 reu00670 reu00785 reu01200 reu01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:reu00260 reu00670 reu01100]
M00975 Betaine degradation, bacteria, betaine => pyruvate [PATH:reu00260 reu01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:reu00270 reu00920 reu01320 reu01200 reu01230 reu01100 reu01110]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:reu00290 reu00770 reu01210 reu01230 reu01100 reu01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:reu00290 reu01230 reu01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:reu00290 reu01210 reu01230 reu01100 reu01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:reu00280 reu01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:reu00300 reu01230 reu01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:reu00220 reu01210 reu01230 reu01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:reu00220 reu01230 reu01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:reu00330 reu01230 reu01100]
M00970 Proline degradation, proline => glutamate [PATH:reu00330 reu01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:reu00340 reu01230 reu01100 reu01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:reu00340 reu01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:reu00400 reu01230 reu01100 reu01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:reu00400 reu01230 reu01100 reu01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:reu00400 reu01230 reu01100 reu01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:reu00400 reu01230 reu01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:reu00350 reu01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:reu00250 reu00650 reu01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:reu00480 reu01240 reu01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:reu00520 reu01250 reu01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:reu00520]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:reu00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:reu00520 reu01250 reu01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:reu00541 reu01250 reu01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:reu00521 reu00523 reu00541 reu01250 reu01100 reu01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:reu00760 reu01240 reu01100]
M00622 Nicotinate degradation, nicotinate => fumarate [PATH:reu00760 reu01100 reu01120]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:reu00770 reu01240 reu01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:reu00780 reu01240 reu01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:reu00785 reu01240 reu01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:reu00790 reu00670 reu01240 reu01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:reu00790 reu01240 reu01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:reu00790 reu01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:reu00860 reu01240 reu01100 reu01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:reu00860 reu01240 reu01100]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:reu00130 reu01240 reu01100 reu01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00548 Benzene degradation, benzene => catechol [PATH:reu00361 reu00362 reu01220 reu01100 reu01120]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:reu00362 reu00622 reu01220 reu01100 reu01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:reu00362 reu01220 reu01100 reu01120]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:reu00362 reu00622 reu01220 reu01100 reu01120]
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:reu00360 reu01220 reu01100 reu01120]

Gene set
Pathogenicity
Drug resistance
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation