KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:senl00010 senl01200 senl01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:senl00010 senl01200 senl01230 senl01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:senl00010 senl00020 senl01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:senl00010 senl00020 senl00620 senl00785 senl01200 senl01210 senl01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:senl00020 senl01200 senl01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:senl00020 senl01200 senl01210 senl01230 senl01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:senl00020 senl01200 senl01210 senl01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:senl00030 senl01200 senl01100 senl01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:senl00030 senl01200 senl01100 senl01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:senl00030 senl01200 senl01230 senl01100 senl01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:senl00030 senl00230 senl01200 senl01230 senl01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:senl00030 senl01200 senl01100 senl01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:senl00040 senl00030 senl01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:senl00052 senl01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:senl00052 senl01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:senl00053 senl01100 senl01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:senl00500 senl01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:senl00500 senl01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:senl00500 senl01100 senl01110]
M00012 Glyoxylate cycle [PATH:senl00630 senl01200 senl01100 senl01110]
M00982 Methylcitrate cycle [PATH:senl00640 senl00020 senl01200 senl01100 senl01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:senl00620 senl00710 senl01200 senl01100 senl01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:senl00430 senl00620 senl00720 senl01200 senl01100 senl01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:senl00910 senl01310 senl01100 senl01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:senl00920 senl01320 senl01100 senl01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:senl00190 senl01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:senl00190 senl01100]
M00150 Fumarate reductase, prokaryotes [PATH:senl00190 senl01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:senl00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:senl00190 senl01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:senl00190 senl01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:senl00061 senl01212 senl01100]
M00083 Fatty acid biosynthesis, elongation [PATH:senl00061 senl01212 senl01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:senl00061 senl00071 senl01212 senl01100]
M00087 beta-Oxidation [PATH:senl00071 senl01212 senl01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:senl00564 senl01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:senl00230 senl01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:senl00230 senl01232 senl01240 senl01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:senl00230 senl01232 senl01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:senl00230 senl00240 senl01232 senl01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:senl00240 senl01240 senl01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:senl00240 senl01232 senl01240 senl01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:senl00240 senl01232 senl01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:senl00260 senl00680 senl01200 senl01230 senl01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:senl00260 senl01230 senl01100 senl01110]
M00621 Glycine cleavage system [PATH:senl00260 senl00630 senl00670 senl00785 senl01200 senl01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:senl00270 senl00920 senl01320 senl01200 senl01230 senl01100 senl01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:senl00270 senl01230 senl01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:senl00290 senl00770 senl01210 senl01230 senl01100 senl01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:senl00290 senl01230 senl01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:senl00290 senl01210 senl01230 senl01100 senl01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:senl00300 senl01230 senl01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:senl00310 senl01100 senl01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:senl00220 senl01210 senl01230 senl01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:senl00220 senl01230 senl01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:senl00330 senl01230 senl01100]
M00970 Proline degradation, proline => glutamate [PATH:senl00330 senl01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:senl00330 senl01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:senl00330 senl01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:senl00340 senl01230 senl01100 senl01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:senl00340 senl01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:senl00400 senl01230 senl01100 senl01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:senl00400 senl01230 senl01100 senl01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:senl00400 senl01230 senl01100 senl01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:senl00400 senl01230 senl01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:senl00350 senl01220 senl01100 senl01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:senl00480 senl01240 senl01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:senl00520 senl01250 senl01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:senl00520 senl01250 senl01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:senl00520 senl01250 senl01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:senl00520 senl00052 senl01250 senl01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:senl00520 senl01250 senl01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:senl00541 senl01250 senl01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:senl00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:senl00541 senl01250 senl01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:senl00541 senl01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:senl00521 senl00523 senl00541 senl01250 senl01100 senl01110]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:senl00541]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:senl00540 senl01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:senl00730 senl01240 senl01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:senl00730 senl01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:senl00740 senl01240 senl01100 senl01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:senl00750 senl01240 senl01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:senl00760 senl01240 senl01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:senl00770 senl01240 senl01100 senl01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:senl00770 senl01240 senl01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:senl00780 senl01240 senl01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:senl00780 senl01240 senl01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:senl00785 senl01240 senl01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:senl00790 senl00670 senl01240 senl01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:senl00790 senl01240 senl01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:senl00790 senl01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:senl00860 senl01240 senl01100 senl01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:senl00860 senl01240 senl01100 senl01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:senl00860 senl01240 senl01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:senl00860 senl01240 senl01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:senl00130 senl01240 senl01100 senl01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:senl00130 senl01240 senl01100 senl01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:senl00130 senl01240 senl01100 senl01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:senl00900 senl01100 senl01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:senl00900 senl01100 senl01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00696 Multidrug resistance, efflux pump AcrEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation