KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:senq00010 senq01200 senq01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:senq00010 senq01200 senq01230 senq01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:senq00010 senq00020 senq01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:senq00010 senq00020 senq00620 senq00785 senq01200 senq01210 senq01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:senq00020 senq01200 senq01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:senq00020 senq01200 senq01210 senq01230 senq01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:senq00020 senq01200 senq01210 senq01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:senq00030 senq01200 senq01100 senq01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:senq00030 senq01200 senq01100 senq01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:senq00030 senq01200 senq01230 senq01100 senq01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:senq00030 senq00230 senq01200 senq01230 senq01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:senq00030 senq01200 senq01100 senq01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:senq00040 senq00030 senq01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:senq00052 senq01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:senq00052 senq01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:senq00053 senq01100 senq01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:senq00500 senq01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:senq00500 senq01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:senq00500 senq01100 senq01110]
M00012 Glyoxylate cycle [PATH:senq00630 senq01200 senq01100 senq01110]
M00982 Methylcitrate cycle [PATH:senq00640 senq00020 senq01200 senq01100 senq01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:senq00620 senq00710 senq01200 senq01100 senq01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:senq00430 senq00620 senq00720 senq01200 senq01100 senq01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:senq00910 senq01310 senq01100 senq01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:senq00920 senq01320 senq01100 senq01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:senq00190 senq01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:senq00190 senq01100]
M00150 Fumarate reductase, prokaryotes [PATH:senq00190 senq01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:senq00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:senq00190 senq01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:senq00190 senq01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:senq00061 senq01212 senq01100]
M00083 Fatty acid biosynthesis, elongation [PATH:senq00061 senq01212 senq01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:senq00061 senq00071 senq01212 senq01100]
M00087 beta-Oxidation [PATH:senq00071 senq01212 senq01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:senq00564 senq01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:senq00230 senq01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:senq00230 senq01232 senq01240 senq01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:senq00230 senq01232 senq01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:senq00230 senq00240 senq01232 senq01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:senq00240 senq01240 senq01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:senq00240 senq01232 senq01240 senq01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:senq00240 senq01232 senq01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:senq00260 senq00680 senq01200 senq01230 senq01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:senq00260 senq01230 senq01100 senq01110]
M00621 Glycine cleavage system [PATH:senq00260 senq00630 senq00670 senq00785 senq01200 senq01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:senq00270 senq00920 senq01320 senq01200 senq01230 senq01100 senq01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:senq00270 senq01230 senq01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:senq00290 senq00770 senq01210 senq01230 senq01100 senq01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:senq00290 senq01230 senq01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:senq00290 senq01210 senq01230 senq01100 senq01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:senq00300 senq01230 senq01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:senq00310 senq01100 senq01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:senq00220 senq01210 senq01230 senq01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:senq00220 senq01230 senq01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:senq00330 senq01230 senq01100]
M00970 Proline degradation, proline => glutamate [PATH:senq00330 senq01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:senq00330 senq01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:senq00330 senq01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:senq00340 senq01230 senq01100 senq01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:senq00340 senq01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:senq00400 senq01230 senq01100 senq01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:senq00400 senq01230 senq01100 senq01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:senq00400 senq01230 senq01100 senq01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:senq00400 senq01230 senq01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:senq00350 senq01220 senq01100 senq01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:senq00480 senq01240 senq01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:senq00520 senq01250 senq01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:senq00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:senq00520 senq01250 senq01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:senq00520 senq00052 senq01250 senq01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:senq00520]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:senq00541 senq01250 senq01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:senq00541 senq01250 senq01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:senq00541 senq01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:senq00521 senq00523 senq00541 senq01250 senq01100 senq01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:senq00540 senq01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:senq00730 senq01240 senq01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:senq00730 senq01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:senq00740 senq01240 senq01100 senq01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:senq00750 senq01240 senq01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:senq00760 senq01240 senq01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:senq00770 senq01240 senq01100 senq01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:senq00770 senq01240 senq01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:senq00780 senq01240 senq01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:senq00780 senq01240 senq01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:senq00785 senq01240 senq01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:senq00790 senq00670 senq01240 senq01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:senq00790 senq01240 senq01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:senq00790 senq01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:senq00860 senq01240 senq01100 senq01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:senq00860 senq01240 senq01100 senq01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:senq00860 senq01240 senq01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:senq00860 senq01240 senq01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:senq00130 senq01240 senq01100 senq01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:senq00130 senq01240 senq01100 senq01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:senq00130 senq01240 senq01100 senq01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:senq00900 senq01100 senq01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:senq00900 senq01100 senq01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00696 Multidrug resistance, efflux pump AcrEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation