KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sml00010 sml01200 sml01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sml00010 sml01200 sml01230 sml01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sml00010 sml00020 sml00620 sml00785 sml01200 sml01210 sml01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sml00020 sml01200 sml01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sml00020 sml01200 sml01210 sml01230 sml01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sml00020 sml01200 sml01210 sml01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sml00030 sml01200 sml01100 sml01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sml00030 sml01200 sml01100 sml01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sml00030 sml01200 sml01230 sml01100 sml01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sml00030 sml00230 sml01200 sml01230 sml01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:sml00030 sml01200 sml01100 sml01120]

Other carbohydrate metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sml00520 sml01250 sml01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sml00520 sml01250 sml01100]
M00012 Glyoxylate cycle [PATH:sml00630 sml01200 sml01100 sml01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sml00620 sml01200 sml01100 sml01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sml00190 sml01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sml00190 sml01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sml00190 sml01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sml00190 sml01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:sml00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:sml00190 sml01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sml00190 sml01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sml00061 sml01212 sml01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sml00061 sml01212 sml01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sml00061 sml00071 sml01212 sml01100]
M00087 beta-Oxidation [PATH:sml00071 sml01212 sml01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sml00564 sml01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sml00230 sml01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sml00230 sml01232 sml01240 sml01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sml00230 sml01232 sml01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sml00230 sml00240 sml01232 sml01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:sml00230 sml01232 sml01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sml00240 sml01232 sml01240 sml01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sml00240 sml01232 sml01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sml00260 sml01230 sml01100 sml01110]
M00621 Glycine cleavage system [PATH:sml00260 sml00630 sml00785 sml01200 sml01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sml00260 sml01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:sml00260 sml00270 sml01230 sml01100]
M00034 Methionine salvage pathway [PATH:sml00270 sml01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sml00290 sml00770 sml01210 sml01230 sml01100 sml01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sml00290 sml01230 sml01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sml00290 sml01210 sml01230 sml01100 sml01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:sml00280 sml01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sml00300 sml01230 sml01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sml00220 sml01210 sml01230 sml01100]
M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine [PATH:sml00220 sml01230 sml01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sml00330 sml01230 sml01100]
M00970 Proline degradation, proline => glutamate [PATH:sml00330 sml01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sml00340 sml01230 sml01100 sml01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sml00340 sml01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sml00400 sml01230 sml01100 sml01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sml00400 sml01230 sml01100 sml01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sml00400 sml01230 sml01100 sml01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:sml00400 sml01230 sml01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:sml00350 sml01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sml00480 sml01240 sml01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:sml00540 sml01250 sml01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sml00740 sml01240 sml01100 sml01110]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:sml00770 sml01240 sml01100 sml01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sml00770 sml01240 sml01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sml00780 sml01240 sml01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sml00785 sml01240 sml01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sml00790 sml00670 sml01240 sml01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:sml00860 sml01240 sml01100 sml01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sml00521 sml00523 sml00541 sml01250 sml01100 sml01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:sml01501]
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00649 Multidrug resistance, efflux pump AdeABC [PATH:sml01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity