KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:spc00010 spc01200 spc01230 spc01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:spc00010 spc00020 spc01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:spc00010 spc00020 spc00620 spc01200 spc01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:spc00020 spc01200 spc01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:spc00020 spc01200 spc01210 spc01230 spc01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:spc00020 spc01200 spc01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:spc00030 spc01200 spc01100 spc01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:spc00030 spc01200 spc01100 spc01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:spc00030 spc01200 spc01230 spc01100 spc01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:spc00030 spc00230 spc01200 spc01230 spc01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:spc00030 spc01200 spc01100 spc01120]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:spc00500 spc01100]
M00012 Glyoxylate cycle [PATH:spc00630 spc01200 spc01100 spc01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:spc00620 spc01200 spc01100 spc01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:spc00430 spc00620 spc01200 spc01100 spc01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:spc00920 spc01100 spc01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:spc00190]
M00150 Fumarate reductase, prokaryotes [PATH:spc00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:spc00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:spc00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:spc00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:spc00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:spc00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:spc00190]

Lipid metabolism
Fatty acid metabolism
M00083 Fatty acid biosynthesis, elongation [PATH:spc00061 spc01212 spc01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:spc00061 spc00071 spc01212 spc01100]
M00087 beta-Oxidation [PATH:spc00071 spc01212 spc01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:spc00564 spc01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:spc00230 spc01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:spc00230 spc01240 spc01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:spc00230 spc01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:spc00240 spc01240 spc01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP => dCTP [PATH:spc00240]
M00938 Pyrimidine deoxyribonuleotide biosynthesis, UDP => dTTP [PATH:spc00240]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:spc00260 spc00680 spc01200 spc01230 spc01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:spc00260 spc01230 spc01100 spc01110]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:spc00270 spc00920 spc01200 spc01230 spc01100 spc01110]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:spc00270 spc01230 spc01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:spc00290 spc00770 spc01210 spc01230 spc01100 spc01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:spc00290 spc01230 spc01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:spc00290 spc01210 spc01230 spc01100 spc01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:spc00280 spc01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:spc00300 spc01230 spc01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:spc00220 spc01230 spc01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:spc00330 spc01230 spc01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:spc00340 spc01230 spc01100 spc01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:spc00340 spc01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:spc00400 spc01230 spc01100 spc01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:spc00400 spc01230 spc01100 spc01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:spc00400 spc01230 spc01100 spc01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:spc00400 spc01230 spc01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:spc00480 spc01240 spc01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:spc00540 spc01100]
M00063 CMP-KDO biosynthesis [PATH:spc00540 spc01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:spc00730 spc01240 spc01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:spc00740 spc01240 spc01100 spc01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:spc00750 spc01240 spc01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:spc00760 spc01240 spc01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:spc00770 spc01240 spc01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:spc00780 spc01240 spc01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:spc00785 spc01240 spc01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:spc00790 spc00670 spc01240 spc01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:spc00790 spc01240 spc01100]
M00140 C1-unit interconversion, prokaryotes [PATH:spc00670 spc01240 spc01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:spc00860 spc01240 spc01100 spc01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:spc00860 spc01240 spc01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:spc00130 spc01240 spc01100 spc01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:spc00130 spc01240 spc01100 spc01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:spc00521 spc00523 spc00541 spc01100 spc01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00745 Imipenem resistance, repression of porin OprD

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation