KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:xcn00010 xcn01200 xcn01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:xcn00010 xcn01200 xcn01230 xcn01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:xcn00010 xcn00020 xcn00620 xcn00785 xcn01200 xcn01210 xcn01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:xcn00020 xcn01200 xcn01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:xcn00020 xcn01200 xcn01210 xcn01230 xcn01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:xcn00020 xcn01200 xcn01210 xcn01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:xcn00030 xcn01200 xcn01100 xcn01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P [PATH:xcn00030 xcn01200 xcn01100 xcn01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P [PATH:xcn00030 xcn01200 xcn01230 xcn01100 xcn01120]
M00005 PRPP biosynthesis, ribose-5P => PRPP [PATH:xcn00030 xcn00230 xcn01200 xcn01230 xcn01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:xcn00030 xcn01200 xcn01100 xcn01120]

Other carbohydrate metabolism
M00061 Glucuronate degradation, glucuronate => pyruvate + glyceraldehyde-3P [PATH:xcn00040 xcn00030 xcn01100]
M00552 Galactonate degradation, De Ley-Doudoroff pathway, galactonate => glycerate-3P [PATH:xcn00052 xcn01100]
M00012 Glyoxylate cycle [PATH:xcn00630 xcn01200 xcn01100 xcn01110]
M00982 Methylcitrate cycle [PATH:xcn00640 xcn00020 xcn01200 xcn01100 xcn01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:xcn00620 xcn00710 xcn01200 xcn01100 xcn01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:xcn00920 xcn01320 xcn01100 xcn01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:xcn00190 xcn01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:xcn00190 xcn01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:xcn00190 xcn01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:xcn00190 xcn01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:xcn00190 xcn01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:xcn00190 xcn01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:xcn00190 xcn01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:xcn00061 xcn01212 xcn01100]
M00083 Fatty acid biosynthesis, elongation [PATH:xcn00061 xcn01212 xcn01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:xcn00061 xcn00071 xcn01212 xcn01100]
M00087 beta-Oxidation [PATH:xcn00071 xcn01212 xcn01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:xcn00564 xcn01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:xcn00230 xcn01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:xcn00230 xcn01232 xcn01240 xcn01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:xcn00230 xcn01232 xcn01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:xcn00230 xcn00240 xcn01232 xcn01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:xcn00230 xcn01232 xcn01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:xcn00240 xcn01232 xcn01240 xcn01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:xcn00240 xcn01232 xcn01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:xcn00260 xcn01230 xcn01100 xcn01110]
M00621 Glycine cleavage system [PATH:xcn00260 xcn00630 xcn00670 xcn00785 xcn01200 xcn01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:xcn00260 xcn00670 xcn01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:xcn00260 xcn00270 xcn00670 xcn01230 xcn01100]
M00034 Methionine salvage pathway [PATH:xcn00270 xcn01100]
M00035 Methionine degradation [PATH:xcn00270 xcn00670 xcn01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:xcn00290 xcn00770 xcn01210 xcn01230 xcn01100 xcn01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:xcn00290 xcn01230 xcn01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:xcn00290 xcn01210 xcn01230 xcn01100 xcn01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:xcn00280 xcn01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:xcn00300 xcn01230 xcn01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:xcn00220 xcn01210 xcn01230 xcn01100]
M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine [PATH:xcn00220 xcn01230 xcn01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:xcn00330 xcn01230 xcn01100]
M00970 Proline degradation, proline => glutamate [PATH:xcn00330 xcn01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:xcn00340 xcn01230 xcn01100 xcn01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:xcn00340 xcn01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:xcn00400 xcn01230 xcn01100 xcn01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:xcn00400 xcn01230 xcn01100 xcn01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:xcn00400 xcn01230 xcn01100 xcn01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:xcn00400 xcn01230 xcn01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:xcn00350 xcn01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:xcn00480 xcn01240 xcn01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:xcn00470 xcn01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:xcn00520 xcn01250 xcn01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:xcn00520 xcn01250 xcn01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:xcn00520 xcn01250 xcn01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:xcn00520 xcn01250 xcn01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:xcn00520 xcn00052 xcn01250 xcn01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:xcn00520 xcn00053 xcn01250 xcn01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:xcn00520 xcn00051 xcn01250 xcn01100]
M00063 CMP-KDO biosynthesis, ribulose-5P => CMP-KDO [PATH:xcn00541 xcn01250 xcn01100]
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha [PATH:xcn00521 xcn00523 xcn00541 xcn01250 xcn01100 xcn01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:xcn00740 xcn01240 xcn01100 xcn01110]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:xcn00770 xcn01240 xcn01100 xcn01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:xcn00770 xcn01240 xcn01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:xcn00780 xcn01240 xcn01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:xcn00785 xcn01240 xcn01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:xcn00790 xcn00670 xcn01240 xcn01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:xcn00790 xcn01240 xcn01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:xcn00790 xcn01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:xcn00860 xcn01240 xcn01100 xcn01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:xcn00860 xcn01240 xcn01100 xcn01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:xcn00860 xcn01240 xcn01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Biosynthesis of other compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:xcn01501]

Plant pathogenicity
M00660 Xanthomonas spp. pathogenicity signature, T3SS and effectors

Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation