KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:ypr00010 ypr01200 ypr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:ypr00010 ypr01200 ypr01230 ypr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:ypr00010 ypr00020 ypr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ypr00010 ypr00020 ypr00620 ypr00785 ypr01200 ypr01210 ypr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:ypr00020 ypr01200 ypr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:ypr00020 ypr01200 ypr01210 ypr01230 ypr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:ypr00020 ypr01200 ypr01210 ypr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:ypr00030 ypr01200 ypr01100 ypr01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:ypr00030 ypr01200 ypr01100 ypr01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:ypr00030 ypr01200 ypr01230 ypr01100 ypr01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:ypr00030 ypr00230 ypr01200 ypr01230 ypr01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:ypr00030 ypr01200 ypr01100 ypr01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:ypr00040 ypr00030 ypr01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:ypr00040 ypr00030 ypr01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ypr00052 ypr01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:ypr00500 ypr01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:ypr00500 ypr01100]
M00012 Glyoxylate cycle [PATH:ypr00630 ypr01200 ypr01100 ypr01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:ypr00620 ypr00710 ypr01200 ypr01100 ypr01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ypr00430 ypr00620 ypr00720 ypr01200 ypr01100 ypr01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:ypr00910 ypr01310 ypr01100 ypr01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:ypr00920 ypr01320 ypr01100 ypr01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:ypr00190 ypr01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:ypr00190 ypr01100]
M00150 Fumarate reductase, prokaryotes [PATH:ypr00190 ypr01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:ypr00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:ypr00190 ypr01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:ypr00190 ypr01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:ypr00061 ypr01212 ypr01100]
M00083 Fatty acid biosynthesis, elongation [PATH:ypr00061 ypr01212 ypr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:ypr00061 ypr00071 ypr01212 ypr01100]
M00087 beta-Oxidation [PATH:ypr00071 ypr01212 ypr01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ypr00564 ypr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ypr00230 ypr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ypr00230 ypr01232 ypr01240 ypr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ypr00230 ypr01232 ypr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ypr00230 ypr00240 ypr01232 ypr01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:ypr00240 ypr01240 ypr01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ypr00240 ypr01232 ypr01240 ypr01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:ypr00240 ypr01232 ypr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:ypr00260 ypr00680 ypr01200 ypr01230 ypr01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:ypr00260 ypr01230 ypr01100 ypr01110]
M00621 Glycine cleavage system [PATH:ypr00260 ypr00630 ypr00670 ypr00785 ypr01200 ypr01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:ypr00260 ypr00670 ypr01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:ypr00270 ypr00920 ypr01320 ypr01200 ypr01230 ypr01100 ypr01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:ypr00270 ypr01230 ypr01100]
M00034 Methionine salvage pathway [PATH:ypr00270 ypr01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ypr00290 ypr00770 ypr01210 ypr01230 ypr01100 ypr01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ypr00290 ypr01230 ypr01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ypr00290 ypr01210 ypr01230 ypr01100 ypr01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:ypr00300 ypr01230 ypr01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:ypr00220 ypr01210 ypr01230 ypr01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:ypr00220 ypr01230 ypr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:ypr00330 ypr01230 ypr01100]
M00970 Proline degradation, proline => glutamate [PATH:ypr00330 ypr01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:ypr00330 ypr01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:ypr00340 ypr01230 ypr01100 ypr01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:ypr00340 ypr01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:ypr00400 ypr01230 ypr01100 ypr01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:ypr00400 ypr01230 ypr01100 ypr01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:ypr00400 ypr01230 ypr01100 ypr01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:ypr00400 ypr01230 ypr01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:ypr00350 ypr01220 ypr01100 ypr01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:ypr00480 ypr01240 ypr01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:ypr00520 ypr01250 ypr01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:ypr00520 ypr01250 ypr01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:ypr00520 ypr01250 ypr01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:ypr00520 ypr00052 ypr01250 ypr01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:ypr00541 ypr01250 ypr01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:ypr00541]
M01028 GDP-DDmanHep biosynthesis, sedoheptulose-7P => GDP-DDmanHep [PATH:ypr00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:ypr00541 ypr01250 ypr01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:ypr00541 ypr01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:ypr00540 ypr01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:ypr00730 ypr01240 ypr01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ypr00740 ypr01240 ypr01100 ypr01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:ypr00750 ypr01240 ypr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:ypr00760 ypr01240 ypr01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:ypr00770 ypr01240 ypr01100 ypr01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:ypr00770 ypr01240 ypr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:ypr00780 ypr01240 ypr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:ypr00785 ypr01240 ypr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:ypr00790 ypr00670 ypr01240 ypr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:ypr00790 ypr01240 ypr01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:ypr00790 ypr01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:ypr00860 ypr01240 ypr01100 ypr01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:ypr00860 ypr01240 ypr01100 ypr01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:ypr00130 ypr01240 ypr01100 ypr01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:ypr00130 ypr01240 ypr01100 ypr01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:ypr00130 ypr01240 ypr01100 ypr01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00918 Aerobactin biosynthesis, lysine => aerobactin [PATH:ypr00997 ypr01100 ypr01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation