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Entry Name Description Category Pathway
H00363 Candidiasis Candidiasis is a fungal infection with Candida species, predominantly with Candida albicans. Invasive candidiasis is a major cause of morbidity and mortality in the intensive care unit (ICU) setting, causing ... Fungal infectious disease
H00364 Cryptococcosis Cryptococcus is a pathogenic yeast that causes opportunistic infection, especially in the immunocompromised patient. It mainly infects the central nervous system and causes meningitis. Cryptococcal lung ... Fungal infectious disease
H00365 Herpes simplex virus infection
HSV infection
Herpes simplex virus infection is caused by Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2), Simplex viruses in the order Herpesvirales of dsDNA viruses. Humans are the only ... Viral infectious disease hsa05168 Herpes simplex virus 1 infection
H00366 Varicella
Chickenpox
Herpes zoster
Shingles
Varicella-zoster virus (VZV), also known as human herpes virus 3 (HHV-3), is a human pathogen of the Herpesviridae family that has a double-stranded linear DNA genome. Primary infection usually causes ... Viral infectious disease
H00367 Infectious mononucleosis
Epstein-Barr virus (EBV) infection
Epstein-Barr virus (EBV) is a common gammaherpesvirus whose initial infection manifests as infectious mononucleosis that is defined as a clinical triad of fever, pharyngitis, and adenopathy. EBV establishes ... Viral infectious disease hsa05169 Epstein-Barr virus infection
H00368 Cytomegalovirus infection
CMV infection
Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family acquired by late childhood in the majority of individuals. Primary infection is nonspecific but after that the virus becomes ... Viral infectious disease hsa05163 Human cytomegalovirus infection
H00369 Exanthema subitum
Roseolovirus infection
Roseola
Pityriasis rosea
Human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) are human pathogens of members of beta-herpesvirus. Primary infection with HHV-6 and HHV-7 occurs in early childhood and causes short febrile ... Viral infectious disease
H00370 Progressive multifocal leukoencephalopathy Progressive multifocal leukoencephalopathy (PML) is a fatal neurological disorder characterized by destruction of oligodendrocytes by the JC polyomavirus that occurs in immunosuppressed individuals such ... Viral infectious disease
H00371 Adenovirus infection Adenoviruses (Ads) are recognized as etiologic agents of the respiratory and gastrointestinal tracts, eye, and kidney. Ads are rarely associated with severe clinical symptoms in healthy individuals. In ... Viral infectious disease
H00372 Smallpox
Variola
Smallpox is a contagious disease caused by the variola virus, one of the Orthopoxviruses that causes skin eruption and marked toxemia. The disease was officially declared eradicated in 1979 following intensive ... Viral infectious disease
H00373 Mpox (Monkeypox) Human monkeypox is a rare viral zoonotic disease caused by Monkeypox virus of the genus Orthopoxvirus. It occurs mostly in the rain forests of central and western Africa. Human monkeypox has a clinical ... Viral infectious disease
H00374 Viral wart Human papillomaviruses (HPVs) are small DNA viruses of the papovavirus family that can be associated with various skin warts including common warts, plantar warts, plane warts, condyloma acuminatum, Bowenoid ... Viral infectious disease
H00375 SBCAD deficiency
Short-branched-chain acyl-CoA dehydrogenase deficiency
Short-branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency is an autosomal recessive disorder of isoleucine catabolism, caused by mutations in the ACADSB gene. SBCAD dehydrogenates 2-methylbutyryl-CoA ... Inherited metabolic disorder
H00376 Acute poliomyelitis
Polio
Acute poliomyelitis, often called polio, is an infectious disease caused by any of the three serotypes of poliovirus, an enterovirus in the Picornaviridae family of +ssRNA viruses. Only a small proportion ... Viral infectious disease
H00377 Rabies Rabies is a typical zoonotic disease caused by rabies virus that belongs to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. Dogs are the major vectors ... Viral infectious disease
H00378 Lyssavirus infection
Rabies-related virus infection
Lyssaviruses belong to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. The genus Lyssavirus currently includes rabies virus [DS:H00377] and 6 rabies-related ... Viral infectious disease
H00379 Mosquito-borne viral encephalitis Mosquito-borne viral encephalitides are infections of the central nervous system caused by arboviruses (arthropod-borne viruses) and transmitted by mosquitoes. Arboviruses are zoonotic viruses and consist ... Viral infectious disease
H00380 Tick-borne viral encephalitis Tick-borne viral encephalitis is a group of diseases caused by arboviruses closely related to yellow fever, dengue, Japanese encephalitis, and West Nile viruses. It is the most important viral tick-borne ... Viral infectious disease
H00381 Dengue Dengue is an infectious disease caused by Dengue virus (DENV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. Dengue is the most prevalent arboviral infection ... Viral infectious disease
H00382 Mosquito-borne viral fever Mosquito-borne viral fevers are infectious diseases caused by arboviruses (arthropod-borne viruses) and transmitted by mosquitoes. Arboviruses are zoonotic viruses and consist of taxonomically different ... Viral infectious disease
H00383 Arthropod-borne viral fever Arthropod-borne viral fevers are infectious diseases caused by arboviruses (arthropod-borne viruses) and transmitted by mosquitoes, other insects, mites and ticks. Arboviruses are zoonotic viruses and ... Viral infectious disease
H00384 Yellow fever Yellow fever is an infectious disease caused by Yellow fever virus (YFV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. YFV was first isolated in 1927 ... Viral infectious disease
H00385 South American hemorrhagic fever Arenaviruses in the genus Mammarenavirus, the family Arenaviridae of -ssRNA viruses have a natural reservoir in rodents and occasionally infect humans causing viral hemorrhagic fevers. Phylogenetically ... Viral infectious disease
H00386 Lassa fever Lassa fever is an acute viral hemorrhagic illness caused by Lassa virus (LASV), an Old World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. LASV was first discovered ... Viral infectious disease
H00387 B virus infection Macacine herpesvirus 1, also known as B virus, is an alpha-herpesvirus that naturally infects Asiatic macaques. It is transmitted by exposure to contaminated bodily fluids. In macaques, the infection is ... Viral infectious disease
H00388 Non-chlamydial non-gonococcal urethritis Urethritis in men is one of the most common sexually transmitted diseases. Recently, it has been suggested that various pathogenic microorganisms such as Mycoplasma genitalium and Ureaplasma urealyticum ... Bacterial infectious disease
H00389 Hemorrhagic fever with renal syndrome Hemorrhagic fever with renal syndrome (HFRS) is a group of diseases caused by hantaviruses which are members of family Bunyaviridae. Rodents and Soricomorpha species are natural reservoirs of these viruses ... Viral infectious disease
H00390 Hantavirus pulmonary syndrome Hantavirus pulmonary syndrome is an often fatal infectious disease caused by orthohantaviruses in the order Bunyavirales of -ssRNA viruses. Rodents have long been considered to be the primary reservoir ... Viral infectious disease
H00391 Henipavirus infection Hendra virus and Nipah virus are members of a new genus, Henipavirus, in the emerging family Paramyxoviridae. They are bat-borne paramyxoviruses which are responsible for severe disease with high mortality ... Viral infectious disease
H00392 VLCAD deficiency
Very long-chain acyl-CoA dehydrogenase deficiency
Very long chain acyl-coA dehydrogenase (VLCAD) deficiency is an autosomal recessive inborn error of fatty acid oxidation. Three phenotypes of VLCAD deficiency have been identified; an early onset, insidious ... Inherited metabolic disorder, Mitochondrial disease
H00393 Enterovirus infection
Non-polio enterovirus infection
Enteroviruses are a large and diverse group of viruses belonging to the genus Enterovirus in the family Picornaviridae of +ssRNA viruses. Most non-polio enterovirus infections are mild, but some of them ... Viral infectious disease
H00394 Measles Measles is a highly contagious infectious disease caused by the measles virus, a morbillivirus in the Paramyxoviridae family of -ssRNA viruses. The disease may have existed for thousands of years. The ... Viral infectious disease hsa05162 Measles
H00395 Rubella Rubella, also known as German measles, is an infection caused by the rubella virus in the Rubivirus genus, the Togaviridae family of +ssRNA viruses. Congenital rubella syndrome can occur in a developing ... Viral infectious disease
H00396 Mumps Mumps is an acute systemic viral infection classically manifested by inflammation of parotid glands and fever. Mortality is rare, but it is often accompanied by more serious complications such as aseptic ... Viral infectious disease
H00397 Ross River fever Ross River fever is an infectious disease caused by Ross River virus (RRV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Aedes and Culex mosquitoes. RRV was first isolated ... Viral infectious disease
H00398 Influenza Influenza is typically a self-limiting upper respiratory disease caused by three types of influenza viruses: influenza A, B, and C. Influenza A and B viruses cause highly contagious diseases whereas influenza ... Viral infectious disease hsa05164 Influenza A
H00399 Avian influenza
Bird flu
H5N1 flu
Avian influenza is an infectious disease caused by Influenzavirus A that belongs to the genus Alphainfluenzavirus in the Orthomyxoviridae family of -ssRNA virus. Influenzavirus A viruses are species specific ... Viral infectious disease hsa05164 Influenza A
H00400 Parainfluenza infection Human parainfluenza viruses (HPIV) are single-stranded RNA viruses belonging to the paramyxovirus family. They are the second most common causes of pediatric lower respiratory tract disease leading to ... Viral infectious disease
H00401 Respiratory syncytial virus infection
RSV infection
Respiratory syncytial virus (RSV) of the Paramyxoviridae family is a major cause of acute lower respiratory tract illness in infants and young children. It affects the elderly and immunocompromised individuals ... Viral infectious disease
H00402 Severe acute respiratory syndrome
SARS
Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by SARS coronavirus. SARS first emerged in 2002 and gained global from 2002 to 2003. The main mode of transmission of SARS ... Viral infectious disease
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