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Entry Name Description Category Pathway
H01525 22q11.2 deletion syndrome
CATCH22
The 22q11.2 deletion syndrome is the most common microdeletion disorder with an estimated prevalence of 1 in 3000-6000 live births. Most of the patients show the common 3 Mb deletion, but proximal 1.5 ... Chromosomal abnormality
H01526 Legg-Calve-Perthes Disease Legg-Calve-Perthes disease (LCPD) is a particular type of femoral head necrosis occurring in children. It is more common among boys, and bilateral involvement occurs in 8-24% of cases. The disease is usually ... Musculoskeletal disease
H01527 Chronic inflammatory demyelinating polyradiculoneuropathy Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a polyneuropathy that is often disabling, with more than 50% of patients reported as having temporary disability, and about 10% eventually ... Immune system disease; Nervous system disease
H01528 Neuroleptic malignant syndrome Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening side effect to antipsychotic drugs characterized by fever, altered mental status, muscle rigidity, and autonomic dysfunction ... Nervous system disease
H01529 Avascular necrosis of femoral head
Osteonecrosis of the femoral head
Avascular necrosis of the femoral head (ANFH) is one of the most common diseases of osteonecrosis that leads to destruction of the hip joint. Osteonecrosis is a pathological process in which cellular death ... Musculoskeletal disease
H01530 Pinta
Mal del pinto
Carate
Treponemal infections occurring in humans comprise venereal syphilis and the non-venereal endemic treponematoses. The non-venereal endemic treponematoses are yaws, pinta, and endemic syphilis. Pinta, also ... Bacterial infectious disease
H01531 Bejel
Endemic syphilis
Treponemal infections occurring in humans comprise venereal syphilis and the non-venereal endemic treponematoses. The non-venereal endemic treponematoses are yaws, pinta, and bejel. Bejel, also known as ... Bacterial infectious disease
H01532 Gout Gout is a kind of arthritis associated with hyperuricemia. It is triggered due to precipitation and deposition of inflammatory monosodium urate crystals in synovial and other tissues, accompanied by severe ... Musculoskeletal disease
H01533 Japanese encephalitis Japanese encephalitis is an infection of the central nervous system caused by Japanese encephalitis virus (JEV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes ... Viral infectious disease
H01534 Western equine encephalitis Western equine encephalitis is an infection of the central nervous system caused by Western equine encephalitis virus (WEEV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted ... Viral infectious disease
H01535 Eastern equine encephalitis Eastern equine encephalitis is an infection of the central nervous system caused by Eastern equine encephalitis virus (EEEV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted ... Viral infectious disease
H01536 Murray Valley encephalitis
Australian encephalitis
Murray Valley encephalitis, previously known as Australian encephalitis, is an infection of the central nervous system caused by Murray Valley encephalitis virus (MVEV), a flavivirus in the Flaviviridae ... Viral infectious disease
H01537 La Crosse encephalitis
California encephalitis
La Crosse encephalitis is an infection of the central nervous system caused by La Crosse virus (LACV), a phlebovirus in the order Bunyavirales of -ssRNA viruses, and transmitted by Aedes mosquitoes. LACV ... Viral infectious disease
H01538 Hendra virus infection Hendra virus (HeV) is an enveloped, single-stranded negative sense RNA virus that is a prototype member of the genus Henipavirus in the family Paramyxoviridae. HeV is a zoonotic virus that emerged in 1994 ... Viral infectious disease
H01539 Nipah virus infection Nipah virus (NiV) is an enveloped, single-stranded negative sense RNA virus that is a prototype member of the genus Henipavirus in the family Paramyxoviridae. NiV is a zoonotic virus that emerged in Malaysia ... Viral infectious disease
H01540 Chikungunya fever Chikungunya fever is an infectious disease caused by Chikungunya virus (CHIKV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. CHIKV was first recognized ... Viral infectious disease
H01541 Argentine hemorrhagic fever Argentine hemorrhagic fever is an infectious disease caused by Junin virus (JUNV), a New World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. JUNV was first isolated ... Viral infectious disease
H01542 Bolivian hemorrhagic fever Bolivian hemorrhagic fever is an infectious disease caused by Machupo virus (MACV), a New World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. MACV was first isolated ... Viral infectious disease
H01543 Venezuelan hemorrhagic fever Venezuelan hemorrhagic fever is an infectious disease caused by Guanarito virus (GTOV), a New World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. GTOV was first isolated ... Viral infectious disease
H01544 Brazilian hemorrhagic fever Brazilian hemorrhagic fever is an infectious disease caused by Sabia virus (SABV), a New World arenavirus in the Arenaviridae family of -ssRNA viruses, and transmitted by rodents. SABV was first isolated ... Viral infectious disease
H01545 O'nyong-nyong fever O'nyong-nyong fever is an infectious disease caused by O'nyong-nyong virus (ONNV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Anopheles mosquitoes. ONNV was first isolated ... Viral infectious disease
H01546 Mayaro fever Mayaro fever is an infectious disease caused by Mayaro virus (MAYV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted by Haemagogus mosquitoes. MAYV was first isolated in 1954 ... Viral infectious disease
H01547 Venezuelan equine encephalitis Venezuelan equine encephalitis is an infection of the central nervous system caused by Venezuelan equine encephalitis virus (VEEV), an alphavirus in the Togaviridae family of +ssRNA viruses, and transmitted ... Viral infectious disease
H01548 West Nile fever
West Nile virus infection
West Nile fever is an infectious disease caused by West Nile virus (WNV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Culex mosquitoes. WNV was first isolated in 1937 ... Viral infectious disease
H01549 Rift Valley fever Rift Valley fever is an infectious disease caused by Rift Valley fever virus (RVFV), a phlebovirus in the order Bunyavirales of -ssRNA viruses, and transmitted by Aedes and Culex mosquitoes. RVFV was first ... Viral infectious disease
H01550 Bunyamwera fever Bunyamwera fever is an infectious disease caused by Bunyamwera virus (BUNV), an orthobunyavirus in the order Bunyavirales of -ssRNA viruses, and transmitted by Aedes and Anopheles mosquitoes. BUNV was ... Viral infectious disease
H01551 Interstitial cystitis
Bladder pain syndrome
Interstitial cystitis (IC), also referred to as bladder pain syndrome (BPS), is a chronic non-infectious inflammatory condition characterized by recurring discomfort, pain or pressure in the bladder and ... Urinary system disease
H01552 Down syndrome
Trisomy 21
Down syndrome (DS), a genetic condition characterized by mental retardation and distinctive facial appearance, is caused by trisomy of chromosome 21 (HSA21). Down syndrome (DS) is the most common chromosomal ... Chromosomal abnormality
H01553 Zika fever
Zika virus disease
Zika fever is an infectious disease caused by Zika virus (ZIKV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. ZIKV was first isolated in 1947 in the Zika ... Viral infectious disease
H01554 Fallopian tube cancer Fallopian tube cancer is a rare, aggressive gynecologic malignancy. Recent genetic and immunohistochemical studies strongly suggest that high-grade serous adenocarcinoma (SAC) involving the ovary likely ... Cancer
H01555 Merkel cell carcinoma Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine malignancy that exhibits clinically aggressive features and is associated with a poor prognosis. Ultraviolet (UV) radiation may be a cause, and ... Cancer
H01556 Meningioma Meningiomas are the second-most common central nervous system tumor in adults. These tumors arise from arachnoid cells of the meninges, the covering layer of the brain. The majority of meningiomas tend ... Cancer
H01557 Hepatic angiosarcoma Angiosarcoma represents 1 to 2% of soft tissue tumors. It originates from endothelial cells of small blood vessels and may affect a variety of organs, including the retroperitoneum, skeletal muscle, subcutis ... Cancer
H01558 Parathyroid carcinoma Parathyroid carcinoma (PC) is a highly aggressive endocrine tumor, with an annual incidence of less than 1 per million. Over 90% of patients present with excess parathyroid hormone (PTH), representing ... Cancer
H01559 Oropharyngeal cancer Oropharyngeal cancer is a generic term that includes tumors arising within the anatomic confines of the posterior pharyngeal wall, soft palate, tonsillar region and posterior one-third (base) of the tongue ... Cancer
H01560 Alkhumra hemorrhagic fever Alkhumra hemorrhagic fever is a severe, often fatal, infectious disease caused by Alkhumra hemorrhagic fever virus (AHFV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by ... Viral infectious disease
H01561 Chiari malformation
Arnold-Chiari syndrome
Chiari malformations, also known as Arnold-Chiari syndrome, is a group of syndromes consisting of different kinds of pathologic conditions of the posterior fossa development. They are congenital in most ... Congenital malformation
H01562 Patau syndrome
Trisomy 13
Patau syndrome, also known as trisomy 13, is a chromosomal disorder characterized by the severe clinical picture of multiple congenital anomalies. It is one of the least common autosomal trisomies among ... Chromosomal abnormality
H01563 HIV infection The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS). Two types of HIV has been characterized ... Viral infectious disease hsa05170 Human immunodeficiency virus 1 infection
H01564 Edwards syndrome
Trisomy 18
Edwards syndrome, also known as trisomy 18, is a chromosomal disorder due to the presence of an extra chromosome 18, either full, mosaic trisomy, or partial trisomy 18q. This disease is the second-most ... Chromosomal abnormality
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