Integrated stress response (ISR) signaling pathway - Homo sapiens (human)

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• nt06552 Integrated stress response (ISR) signaling pathway
  • N02046 Formation of the ternary complex (TC) for ribosomal translation initiation
  • N02047 EIF2B inhibition by phosphorylation of eIF2alpha
  • N02048 Inactive complex formation by phosphorylation of eIF2alpha
  • N02049 Dephosphorylation of p-eIF2alpha
  • N02050 OMA1-DELE1-HRI pathway
  • N02051 OMA1 inhibition by CHCHD2 and CHCHD10
  • N02052 DELE1degradation by LONP1
  • N02053 Adaptive response of the ISR during mitochondrial stress