KEGG ORTHOLOGY: K06792

ORTHOLOGY: K06792

Entry

K06792                      KO

Symbol

AGC1, CSPG1

Name

aggrecan 1

Disease

H00448

Familial osteochondritis dissecans

H00765

Spondyloepiphyseal dysplasia, Kimberley type

H02187

Spondyloepimetaphyseal dysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans
    K06792  AGC1, CSPG1; aggrecan 1
   00536 Glycosaminoglycan binding proteins
    K06792  AGC1, CSPG1; aggrecan 1
   04091 Lectins
    K06792  AGC1, CSPG1; aggrecan 1
Proteoglycans [BR:ko00535]
Extracellular matrix (ECM) proteoglycans
  Aggrecan / versican family
   K06792  AGC1, CSPG1; aggrecan 1
Glycosaminoglycan binding proteins [BR:ko00536]
Hyaluronan
  Extracellular matrix or blood plasma proteins
   K06792  AGC1, CSPG1; aggrecan 1
Lectins [BR:ko04091]
C-Type lectins
  Group 1: Proteoglycan core proteins
   K06792  AGC1, CSPG1; aggrecan 1

Genes

HSA:

176(ACAN)

PTR:	453629(ACAN)

PPS:	100969652(ACAN)

GGO:	101140474(ACAN)

PON:	100432072(ACAN)

NLE:	115835536(ACAN)

HMH:	116482621(ACAN)

MCC:	698498(ACAN)

MCF:	102133327(ACAN)

MTHB:

126958935

MNI:	105488344(ACAN)

CSAB:

103231142(ACAN)

CATY:

105592419(ACAN)

PANU:

101017261(ACAN)

TGE:	112628968(ACAN)

MLEU:

105544073(ACAN)

RRO:	104661607(ACAN)

RBB:	108535782(ACAN)

TFN:	117070247(ACAN)

PTEH:

111522897(ACAN)

CANG:

105516220(ACAN)

CJC:	100385452(ACAN)

SBQ:	101045734(ACAN)

CIMI:

108287603(ACAN)

CSYR:

103273187(ACAN)

MMUR:

105884697(ACAN)

LCAT:

123645156(ACAN)

PCOQ:

105809823(ACAN)

OGA:	100953762(ACAN)

MMU:	11595(Acan)

MCAL:

110298749(Acan)

MPAH:

110319196(Acan)

RNO:	58968(Acan)

MCOC:

116100594(Acan)

ANU:	117720061(Acan)

MUN:	110552443(Acan)

CGE:	100764201(Acan)

MAUA:

101844842(Acan)

PROB:

127238141(Acan)

PLEU:

114699877(Acan)

MORG:

121449159(Acan)

MFOT:

126508669

AAMP:

119802821(Acan)

NGI:	103749920(Acan)

HGL:	101725814(Acan)

CPOC:

100731672(Acan)

DORD:

105982416(Acan)

DSP:	122123971(Acan)

PLOP:

125368079

NCAR:

124976097

MMMA:

107148439(Acan)

OCU:

100009079

OPI:	101524193(ACAN)

GVR:	103585688(ACAN)

CFA:	403828(ACAN)

CLUD:

112653562(ACAN)

VVP:	112921800(ACAN)

VLG:	121489635(ACAN)

NPO:	129510408(ACAN)

AML:	100473183(ACAN)

UMR:	103660252(ACAN)

UAH:	113263578(ACAN)

UAR:	123802448(ACAN)

ELK:

111152552

LLV:

125105292

MPUF:

101691264(ACAN)

MNP:	131999057(ACAN)

MLK:	131835623(ACAN)

NVS:	122893741(ACAN)

ORO:	101380960(ACAN)

EJU:	114223311(ACAN)

ZCA:	113908560(ACAN)

MLX:	118023193(ACAN)

NSU:	110572288(ACAN)

LWW:	102734563(ACAN)

FCA:	101084542(ACAN)

PYU:	121042222(ACAN)

PCOO:

112855466(ACAN)

PBG:	122468239(ACAN)

PVIV:

125167166(ACAN)

LRUF:

124517385

PTG:	102965171(ACAN)

PPAD:

109273416(ACAN)

AJU:

106965860

HHV:	120220318(ACAN)

BTA:	280985(ACAN)

BOM:	102278312(ACAN)

BIU:	109575159(ACAN)

BBUB:

102399993(ACAN)

BBIS:

104989372(ACAN)

CHX:	102188900(ACAN)

OAS:	443001(ACAN)

BTAX:

128066759(ACAN)

ODA:	120875645(ACAN)

CCAD:

122455052(ACAN)

MBEZ:

129550037(ACAN)

SSC:	397255(ACAN)

CFR:	102505596(ACAN)

CBAI:

105069048(ACAN)

CDK:	105094751(ACAN)

VPC:	102528305(ACAN)

BACU:

103017422(ACAN)

BMUS:

118890515(ACAN)

LVE:	103088266(ACAN)

OOR:	101285209(ACAN)

DLE:	111169654(ACAN)

PCAD:

102993892(ACAN)

PSIU:

116749774(ACAN)

NASI:

112414171(ACAN)

ECB:	100033876(ACAN)

EPZ:	103554391(ACAN)

EAI:	106832021(ACAN)

MYB:	102246540(ACAN)

MYD:	102775200(ACAN)

MLF:	102438986(ACAN)

PKL:	118704332(ACAN)

EFUS:

103302780(ACAN)

MNA:	107525540(ACAN)

DRO:	112306050(ACAN)

SHON:

118991981(ACAN)

AJM:	119049137(ACAN)

PDIC:

114488675(ACAN)

PHAS:

123809756(ACAN)

MMF:	118640955(ACAN)

PPAM:

129073898(ACAN)

RFQ:	117018849(ACAN)

PALE:

102881864(ACAN)

PGIG:

120599260(ACAN)

PVP:	105305210(ACAN)

RAY:	107514175(ACAN)

TOD:	119244297(ACAN)

SARA:

101548522(ACAN)

SETR:

126022361(ACAN)

LAV:	100665333(ACAN)

TMU:

101350435

ETF:	101638184(ACAN)

DNM:	101424734(ACAN)

MDO:	100016782(ACAN)

GAS:	123234207(ACAN)

SHR:	100933517(ACAN)

AFZ:

127546906

PCW:	110193191(ACAN)

OAA:	100093246(ACAN)

GGA:	395798(ACAN)

PCOC:

116225394(ACAN)

MGP:	100549278(ACAN)

CJO:	107318818(ACAN)

TPAI:

128075426(ACAN)

LMUT:

125698380(ACAN)

NMEL:

110403783(ACAN)

APLA:

101800654(ACAN)

ACYG:

106036508(ACAN)

CATA:

118251990(ACAN)

AFUL:

116493574(ACAN)

TGU:	100229255(ACAN)

LSR:	110474194(ACAN)

SCAN:

103816076(ACAN)

PMOA:

120508999(ACAN)

OTC:	121343357(ACAN)

PRUF:

121354359(ACAN)

GFR:	102036127(ACAN)

FAB:	101808742(ACAN)

OMA:	130257574(ACAN)

PHI:	102099619(ACAN)

PMAJ:

107209176(ACAN)

CCAE:

111934038(ACAN)

CCW:	104684086(ACAN)

CBRC:

103621354(ACAN)

ETL:	114058017(ACAN)

ZAB:	102066002(ACAN)

ACHL:

103804396(ACAN)

SVG:	106859221(ACAN)

MMEA:

130573377(ACAN)

HRT:	120758732(ACAN)

FPG:	101911418(ACAN)

FCH:	102049696(ACAN)

CLV:	102090211(ACAN)

EGZ:	104123603(ACAN)

NNI:	104017083(ACAN)

PCRI:

104028337(ACAN)

PLET:

104625665(ACAN)

EHS:	104508447(ACAN)

PCAO:

104047610

ACUN:

113484187(ACAN)

TALA:

104357705(ACAN)

PADL:

103926372(ACAN)

AFOR:

103896729(ACAN)

ACHC:

115342283(ACAN)

HALD:

104320878

HLE:	104834556(ACAN)

AGEN:

126043601

GCL:

127020546

CCRI:

104157081

CSTI:

104555769(ACAN)

CMAC:

104478387

MUI:	104542693(ACAN)

BREG:

104629889

GSTE:

104263029

LDI:

104342962

MNB:	103781235(ACAN)

OHA:	104332080(ACAN)

NNT:

104402697

SHAB:

115613125(ACAN)

DPUB:

104303356(ACAN)

PGUU:

104460991

ACAR:

104528608(ACAN)

CPEA:

104394447(ACAN)

AVIT:

104279845

CVF:	104288464(ACAN)

RTD:	128914880(ACAN)

CUCA:

104059698(ACAN)

TEO:	104383949(ACAN)

BRHI:

104489651(ACAN)

AAM:	106497410(ACAN)

AROW:

112970073(ACAN)

NPD:	112944815(ACAN)

TGT:	104567720(ACAN)

DNE:	112995967(ACAN)

SCAM:

104148197(ACAN)

ASN:	102383128(ACAN)

AMJ:	102558388(ACAN)

CPOO:

109309120(ACAN)

GGN:	109288507(ACAN)

PSS:	102443962(ACAN)

CMY:	102942741(ACAN)

CCAY:

125644139(ACAN)

DCC:	119862436(ACAN)

CPIC:

101939274(ACAN)

TST:	117884148(ACAN)

CABI:

116840122(ACAN)

MRV:	120374137(ACAN)

ACS:	100554326(acan)

ASAO:

132762306(ACAN)

PVT:	110072934(ACAN)

SUND:

121934400(ACAN)

PBI:	103067381(ACAN)

PMUR:

107293678(ACAN)

CTIG:

120315253(ACAN)

TSR:	106540473(ACAN)

PGUT:

117669864(ACAN)

APRI:

131184561(ACAN)

PTEX:

113442000(ACAN)

NSS:	113421461(ACAN)

VKO:	123027689(ACAN)

PMUA:

114584247(ACAN)

PRAF:

128401670(ACAN)

ZVI:	118093154(ACAN)

HCG:	128335196(ACAN)

GJA:	107124468(ACAN)

STOW:

125424745(ACAN)

EMC:	129345251(ACAN)

XLA:	108710307(acan.L) 108712312

XTR:	100491091(acan)

NPR:	108799658(ACAN)

RTEM:

120931192(ACAN)

BBUF:

120985940(ACAN)

BGAR:

122927539(ACAN)

MUO:	115459885(ACAN)

GSH:	117348712(ACAN)

DRE:	497505(acana) 559593(acanb)

SRX:	107707857 107716680 107730253

SANH:

107679623 107694087

SGH:	107562499 107574449

CCAR:

109063329 109092821

CAUA:

113043285 113054611 113106231 113110272

CGIB:

127961856 128014711

PTET:

122349472(acana)

LROH:

127168469(acana)

OMC:	131534398(acanb) 131543567(acana)

PPRM:

120459107(acanb) 120469609(acana)

RKG:	130077107(acana) 130085356(acanb)

MAMB:

125247467(acanb) 125265137(acana)

CIDE:

127506617 127515406

MASI:

127415591 127436212 127443216

TROS:

130551952(acanb) 130558422(acana)

TDW:	130413824(acanb) 130427709(acana)

MANU:

129433394(acanb) 129447239(acana)

IPU:	108259193(acana) 108268788(acanb)

IFU:	128602819(acana) 128611535(acanb)

PHYP:

113529161 113540959

SMEO:

124380071(acana) 124385722(acanb)

TFD:	113635695(acanb) 113636669(acana)

TVC:	132838736(acana) 132856373(acanb)

AMEX:

103021642 103029855

CMAO:

118806799(acanb) 118817622(acana)

EEE:

113579690

CHAR:

105908085

TRU:	101069140 101078700(acan)

TFS:	130517871 130535709(acanb)

TNG:	GSTEN00019684G001

LCO:	104922400(acan) 104927251

NCC:

104961864

TBEN:

117471243 117497198(acanb)

CGOB:

115003465 115009444

PGEO:

117442086 117448519

GACU:

117533635 117559112(acanb)

EMAC:

134860213(acanb) 134862579

ELY:	117251429 117261630(acanb)

EFO:	125886936(acanb) 125899631

PLEP:

121950122(acanb)

SLUC:

116046791(acanb) 116067268

ECRA:

117949293(acanb) 117961771

ESP:	116686763 116694325

PFLV:

114555422 114560096

GAT:	120831250(acana)

PPUG:

119195891

AFB:	129105360 129108002(acanb)

CLUM:

117725356 117731960

PSWI:

130192994 130195910(acanb)

MSAM:

119884869 119894406

SCHU:

122874618(acanb) 122880245

CUD:	121514700(acanb)

ALAT:

119018819 119025021

MZE:	101465412 101477422

ONL:	100701134 100711965

OAU:	116313999 116320048 116323944

OLA:	101156813 101165132

OML:	112141877 112151943(acanb)

CSAI:

133444525 133458580

XMA:

102226581

XCO:	114135831 114142480

XHE:

116718587

PRET:

103462965 103465686(acan)

PFOR:

103152834 103155224

PLAI:

106960856 106961165

PMEI:

106924562 106927942

GAF:	122824669 122835979(acanb)

PPRL:

129354055 129363397(acanb)

CVG:

107091095

CTUL:

119793968(acanb) 119798828

GMU:	124856089(acanb) 124866595

NFU:	107382072 107388387(acan)

KMR:	108245723(acanb)

ALIM:

106526642

NWH:	119416087(acanb)

AOCE:

111570088 111570708

MCEP:

125004956 125015441(acanb)

CSEM:

103379793(acan)

POV:

109624122

SSEN:

122772584 122775483(acanb)

HHIP:

117759263 117763647(acanb)

HSP:	118106468 118110201(acanb)

SMAU:

118302774 118315777(acanb)

LCF:	108889283 108894132

SDU:	111223064 111229887(acan)

SLAL:

111650427(acan) 111656631

XGL:	120786950 120792434 120792904(acanb)

HCQ:

109518270

SSCV:

125970063

SBIA:

133502073

PEE:	133395517 133403191(acanb)

PTAO:

133473346 133478026(acanb)

BPEC:

110169168

MALB:

109954465 109974852

BSPL:

114852303

SJO:	128359082(acanb) 128364076

SASA:

106561101 106584646

STRU:

115166935 115192848 115197114 115203375

OTW:	112233003 112264245

OMY:	110491947(acanb) 110496314 110503942 110506142 110506145 110521245 110523418 110534753

OGO:	124017830 124039656

ONE:	115134660(acan)

OKI:	109866854 109878480 109898301

OKE:	118358793 118377706 118396390

SALP:

111962093 111971677

SNH:	120052877 120052906 120065996

CCLU:

121532119 121583004 123490752

ELS:	105028552(acan)

SFM:

108941268

PKI:

111844964

AANG:

118226964

LOC:	102696245(acan)

PSPA:

121294356 121299105 121306980(bcan)

ARUT:

PSEX:

CMK:

CPLA:

LERI:

ATEN:

Reference

PMID:16185673

Authors

Buzas EI, Vegvari A, Murad YM, Finnegan A, Mikecz K, Glant TT

Title

T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.

Journal

Cell Immunol 235:98-108 (2005)
DOI:10.1016/j.cellimm.2004.08.006

Sequence

[mmu:11595]

LinkDB

DBGET integrated database retrieval system