KEGG   ORTHOLOGY: K10628
Entry
K10628                      KO                                     
Symbol
RAG1
Name
V(D)J recombination-activating protein 1 [EC:2.3.2.27]
Pathway
map04068  FoxO signaling pathway
map05340  Primary immunodeficiency
Disease
H00092  T-B-Severe combined immunodeficiency
H01244  T+B+Severe combined immunodeficiencies (SCIDs)
H02554  Omenn syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K10628  RAG1; V(D)J recombination-activating protein 1
 09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    K10628  RAG1; V(D)J recombination-activating protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10628  RAG1; V(D)J recombination-activating protein 1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10628  RAG1; V(D)J recombination-activating protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K10628  RAG1; V(D)J recombination-activating protein 1
Genes
HSA: 5896(RAG1)
PTR: 466489(RAG1)
PPS: 100981734(RAG1)
GGO: 101149904(RAG1)
PON: 100447109(RAG1)
NLE: 100595879(RAG1)
HMH: 116476346(RAG1)
MCC: 697322(RAG1)
MTHB: 126936613
MNI: 105471573(RAG1)
CSAB: 103237538(RAG1)
CATY: 105586810(RAG1)
PANU: 101000449(RAG1)
TGE: 112606562(RAG1)
MLEU: 105534672(RAG1)
RRO: 104658365(RAG1)
RBB: 108535562(RAG1)
TFN: 117080231(RAG1)
PTEH: 111521902(RAG1)
CANG: 105510803(RAG1)
CJC: 100395720(RAG1)
SBQ: 101033618(RAG1)
CIMI: 108305749(RAG1)
CSYR: 103263672(RAG1)
MMUR: 105856827(RAG1)
LCAT: 123642604(RAG1)
PCOQ: 105814563(RAG1)
OGA: 100946124(RAG1)
MMU: 19373(Rag1)
MCAL: 110312570(Rag1)
MPAH: 110319308(Rag1)
RNO: 84600(Rag1)
MCOC: 116092256(Rag1)
ANU: 117704228(Rag1)
MUN: 110557494(Rag1)
CGE: 100754292(Rag1)
MAUA: 101831007(Rag1)
PROB: 127222197(Rag1)
PLEU: 114710763(Rag1)
MORG: 121440571 121465858(Rag1)
MFOT: 126504714
AAMP: 119815688(Rag1)
NGI: 103749514(Rag1)
HGL: 101724556(Rag1)
CPOC: 100724169(Rag1)
CCAN: 109693568(Rag1)
DORD: 105988108(Rag1)
DSP: 122117923(Rag1)
PLOP: 125362200(Rag1)
NCAR: 124958111
MMMA: 107134509(Rag1)
OCU: 100328950(RAG1)
OPI: 101518064(RAG1)
TUP: 102483075(RAG1)
GVR: 103601166(RAG1)
CFA: 483420(RAG1)
CLUD: 112663497(RAG1)
VVP: 112930593(RAG1)
VLG: 121501482(RAG1)
NPO: 129494043(RAG1)
AML: 100483463(RAG1)
UMR: 103659304(RAG1)
UAH: 113264892(RAG1)
UAR: 123799534(RAG1)
ELK: 111150268
LLV: 125079553
MPUF: 101691963(RAG1)
MNP: 132010628(RAG1)
MLK: 131811460(RAG1)
NVS: 122914305(RAG1)
ORO: 101362361(RAG1)
EJU: 114215206(RAG1)
ZCA: 113915302(RAG1)
MLX: 118015562(RAG1)
NSU: 110575730(RAG1)
LWW: 102729044(RAG1)
FCA: 101096264(RAG1)
PYU: 121043533(RAG1)
PCOO: 112865962(RAG1)
PBG: 122483713(RAG1)
PVIV: 125177159(RAG1)
LRUF: 124506320
PTG: 102960431(RAG1)
PPAD: 109279194(RAG1)
PUC: 125934490
AJU: 106976928
HHV: 120232543(RAG1)
BTA: 506302(RAG1)
BOM: 102286166(RAG1)
BIU: 109569432(RAG1)
BBUB: 102399255(RAG1)
BBIS: 104982478(RAG1)
CHX: 102173108(RAG1)
OAS: 101107384(RAG1)
BTAX: 128060946(RAG1)
ODA: 120876880(RAG1)
CCAD: 122449435(RAG1)
MBEZ: 129554055(RAG1)
SSC: 397506(RAG1)
CFR: 102519940(RAG1)
CBAI: 105076499(RAG1)
CDK: 105106824(RAG1)
VPC: 102541180(RAG1)
BACU: 103019951(RAG1)
BMUS: 118900052(RAG1)
LVE: 103087418(RAG1)
OOR: 101277792(RAG1)
DLE: 111179771(RAG1)
PCAD: 102992940(RAG1)
PSIU: 116758507(RAG1)
NASI: 112404581(RAG1)
ECB: 100049810(RAG1)
EPZ: 103560235(RAG1)
EAI: 106837479(RAG1)
MYB: 102251239(RAG1)
MYD: 102765656(RAG1)
MMYO: 118665126(RAG1)
MLF: 102437119(RAG1)
PKL: 118713380(RAG1)
EFUS: 103290872(RAG1)
MNA: 107531933(RAG1)
DRO: 112303162(RAG1)
SHON: 118983214(RAG1)
AJM: 119036481(RAG1)
PDIC: 114500741(RAG1)
PHAS: 123810057(RAG1)
MMF: 118629065(RAG1)
PPAM: 129080725(RAG1)
HAI: 109381116(RAG1)
RFQ: 117029802(RAG1)
PALE: 102886891(RAG1)
PGIG: 120604320(RAG1)
PVP: 105289982(RAG1)
RAY: 107499250(RAG1)
MJV: 108387879(RAG1)
TOD: 119254533(RAG1)
SARA: 101543481(RAG1)
LAV: 100658301(RAG1)
TMU: 101345589
ETF: 101659128(RAG1)
DNM: 101436087(RAG1)
MDO: 100011241(RAG1)
GAS: 123254767(RAG1)
SHR: 100922588(RAG1)
AFZ: 127540818
PCW: 110192650(RAG1)
OAA: 100077097(RAG1)
GGA: 423164(RAG1)
PCOC: 116229118(RAG1)
MGP: 100542632(RAG1)
CJO: 107314674(RAG1)
TPAI: 128086645(RAG1)
LMUT: 125694456(RAG1)
NMEL: 110402149(RAG1)
APLA: 101802725(RAG1)
ACYG: 106044339(RAG1)
CATA: 118250846(RAG1)
AFUL: 116489673(RAG1)
TGU: 100224875(RAG1)
LSR: 110484459(RAG1)
SCAN: 103826722(RAG1)
PMOA: 120512572(RAG1)
OTC: 121344849(RAG1)
PRUF: 121360935(RAG1)
GFR: 102041505(RAG1)
FAB: 101817279(RAG1)
OMA: 130254330(RAG1)
PHI: 102105364(RAG1)
PMAJ: 107205242(RAG1)
CCAE: 111930104(RAG1)
CCW: 104694035(RAG1)
CBRC: 103620712(RAG1)
ETL: 114056747(RAG1)
ZAB: 102065378(RAG1)
ACHL: 103806229(RAG1)
SVG: 106851510(RAG1)
MMEA: 130578097(RAG1)
HRT: 120754215(RAG1)
FPG: 101912181(RAG1)
FCH: 102058214(RAG1)
CLV: 102084079(RAG1)
EGZ: 104134047(RAG1)
NNI: 104009614(RAG1)
PCRI: 104023743(RAG1)
PLET: 104613590(RAG1)
EHS: 104502501(RAG1)
PCAO: 104046867(RAG1)
ACUN: 113481163(RAG1)
TALA: 104355454(RAG1)
PADL: 103921677(RAG1)
AFOR: 103901554(RAG1)
ACHC: 115353332(RAG1)
HALD: 104324433(RAG1)
HLE: 104843212(RAG1)
GCL: 127016551
CCRI: 104154463(RAG1)
CSTI: 104549127(RAG1)
CMAC: 104472978(RAG1)
MUI: 104544954(RAG1)
BREG: 104629019(RAG1)
FGA: 104069110(RAG1)
GSTE: 104254405(RAG1)
LDI: 104352254(RAG1)
MNB: 103771037(RAG1)
OHA: 104330075(RAG1)
NNT: 104399014(RAG1)
SHAB: 115607340(RAG1)
DPUB: 104304787(RAG1)
PGUU: 104457453(RAG1)
ACAR: 104529097(RAG1)
CPEA: 104388406(RAG1)
AVIT: 104267081(RAG1)
CVF: 104295804(RAG1)
RTD: 128909473(RAG1)
CUCA: 104056321(RAG1)
TEO: 104374949(RAG1)
BRHI: 104501385(RAG1)
AAM: 106498195(RAG1)
AROW: 112960914(RAG1)
NPD: 112943546(RAG1)
TGT: 104568688(RAG1)
DNE: 112981789(RAG1)
SCAM: 104152882(RAG1)
ASN: 102382683(RAG1)
AMJ: 102566094(RAG1)
CPOO: 109321567(RAG1)
GGN: 109298949(RAG1)
PSS: 102463645(RAG1)
CMY: 102938739(RAG1)
CCAY: 125638709(RAG1)
DCC: 119857312(RAG1)
CPIC: 101945962(RAG1)
TST: 117875755(RAG1)
CABI: 116839269(RAG1)
MRV: 120403948(RAG1)
ACS: 100561999(rag1)
ASAO: 132781777(RAG1)
PVT: 110090247(RAG1)
SUND: 121926574(RAG1)
PBI: 103053491(RAG1)
PMUR: 107293336(RAG1)
CTIG: 120301921(RAG1)
TSR: 106556822(RAG1)
PGUT: 117666164(RAG1)
APRI: 131187525(RAG1)
PTEX: 113438984(RAG1)
NSS: 113410176(RAG1)
VKO: 123026691(RAG1)
PMUA: 114585013(RAG1)
PRAF: 128413601(RAG1)
ZVI: 118080211(RAG1)
HCG: 128322315(RAG1)
GJA: 107114927(RAG1)
STOW: 125426332(RAG1)
EMC: 129323428(RAG1)
XLA: 100337558(rag1.S) 100337559(rag1.L)
XTR: 100145555(rag1)
NPR: 108787814(RAG1)
RTEM: 120917067(RAG1)
BBUF: 120980978(RAG1)
BGAR: 122920775(RAG1)
MUO: 115467957(RAG1)
GSH: 117351993(RAG1)
DRE: 30663(rag1)
SRX: 107720765 107750737
SANH: 107670202 107673232
SGH: 107564618 107581862(rag1)
CCAR: 109051085(rag1)
CAUA: 113066712 113098359(rag1)
CGIB: 127946760 128013896
PTET: 122330494(rag1)
LROH: 127156785(rag1)
OMC: 131534203(rag1)
PPRM: 120468290(rag1)
RKG: 130073701(rag1)
MAMB: 125247634(rag1)
CIDE: 127507634
MASI: 127435893 127437291
TROS: 130551893(rag1)
TDW: 130414440(rag1)
MANU: 129434412(rag1)
IPU: 100304618
IFU: 128618634(rag1)
PHYP: 113529514(rag1)
SMEO: 124392384(rag1)
TFD: 113659958(rag1)
TVC: 132856945(rag1)
AMEX: 103044739(rag1)
CMAO: 118811587(rag1)
EEE: 113589160(rag1)
CHAR: 105900759(rag1)
TRU: 101070902(rag1)
TFS: 130536715(rag1)
TNG: GSTEN00022840G001
LCO: 104925262(rag1)
NCC: 104941239(rag1)
TBEN: 117491583(rag1)
CGOB: 115010005(rag1)
PGEO: 117447719(rag1)
GACU: 117545766(rag1)
EMAC: 134859461(rag1)
ELY: 117262673(rag1)
EFO: 125888099(rag1)
PLEP: 121949718(rag1)
SLUC: 116038814(rag1)
ECRA: 117949482(rag1)
ESP: 116694125(rag1)
PFLV: 114560670(rag1)
GAT: 120809626(rag1)
PPUG: 119196032(rag1)
AFB: 129108694(rag1)
CLUM: 117732553(rag1)
PSWI: 130191542 130195007(rag1)
MSAM: 119893086(rag1)
SCHU: 122875347(rag1)
CUD: 121515499(rag1)
ALAT: 119023798(rag1)
MZE: 101481579(rag1)
ONL: 100706453(rag1)
OAU: 116334536(rag1)
OLA: 101159098(rag1)
OML: 112152924(rag1)
CSAI: 133444701(rag1)
XMA: 102217349(rag1)
XCO: 114151760(rag1)
XHE: 116729925(rag1)
PRET: 103466123(rag1)
PFOR: 103133651 103133653
PLAI: 106945045(rag1)
PMEI: 106921869(rag1)
GAF: 122835446(rag1)
PPRL: 129367612(rag1)
CVG: 107094314(rag1)
CTUL: 119792989(rag1)
GMU: 124879058(rag1)
NFU: 107388984(rag1)
KMR: 108239995(rag1)
ALIM: 106515635(rag1)
NWH: 119416001(rag1)
AOCE: 111563241(rag1)
MCEP: 125014352(rag1)
CSEM: 103380530(rag1)
POV: 109624264(rag1)
SSEN: 122775491(rag1)
HHIP: 117763719(rag1)
HSP: 118109794(rag1)
SMAU: 118315634(rag1)
LCF: 108875106
SDU: 111228675(rag1)
SLAL: 111655336(rag1)
XGL: 120793478(rag1)
HCQ: 109530307(rag1)
SSCV: 125970822
SBIA: 133502211(rag1)
PEE: 133402864(rag1)
PTAO: 133477826(rag1)
BPEC: 110165948(rag1)
MALB: 109968741(rag1)
BSPL: 114857046(rag1)
SJO: 128359014(rag1)
SASA: 106561304(rag1)
STRU: 115197317(rag1)
OTW: 112218685(rag1)
OMY: 100136833(rag1)
OGO: 124002965(rag1)
ONE: 115134151(rag1)
OKI: 109867442(rag1)
OKE: 118395753(rag1)
SALP: 111962443(rag1)
SNH: 120065910(rag1)
CCLU: 121532209(rag1)
ELS: 105018380(rag1)
SFM: 108942182(rag1)
PKI: 111859427(rag1)
AANG: 118214994(rag1)
LOC: 102699115(rag1)
PSPA: 121294529(rag1)
ARUT: 117432346 117434781
PSEX: 120517486(rag1)
LCM: 102354195(RAG1)
CMK: 103175094(rag1)
RTP: 109930497(rag1)
CPLA: 122558078(rag1)
HOC: 132824317(rag1)
LERI: 129705686(rag1)
SPU: 588498(Rag1L)
APLC: 110976285
PJA: 122244374
PCHN: 125048021
MMER: 123561259 123562286
PDAM: 113681585
 » show all
Reference
PMID:20122409
  Authors
Grazini U, Zanardi F, Citterio E, Casola S, Goding CR, McBlane F
  Title
The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining.
  Journal
Mol Cell 37:282-93 (2010)
DOI:10.1016/j.molcel.2009.12.035
  Sequence
[mmu:19373]
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