KEGG   PATHWAY: aang00330
Entry
aang00330                   Pathway                                
Name
Arginine and proline metabolism - Anguilla anguilla (European eel)
Class
Metabolism; Amino acid metabolism
Pathway map
aang00330  Arginine and proline metabolism
aang00330

Module
aang_M00015  Proline biosynthesis, glutamate => proline [PATH:aang00330]
aang_M00047  Creatine pathway [PATH:aang00330]
aang_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:aang00330]
aang_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:aang00330]
aang_M00970  Proline degradation, proline => glutamate [PATH:aang00330]
aang_M00972  Proline metabolism [PATH:aang00330]
Other DBs
GO: 0006525 0006560
Organism
Anguilla anguilla (European eel) [GN:aang]
Gene
118227169  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
118224621  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
118215468  creatine kinase S-type, mitochondrial-like isoform X1 [KO:K00933] [EC:2.7.3.2]
118230473  creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
118231642  creatine kinase B-type-like [KO:K00933] [EC:2.7.3.2]
118212267  creatine kinase S-type, mitochondrial-like isoform X1 [KO:K00933] [EC:2.7.3.2]
118206659  creatine kinase S-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
118207497  creatine kinase, testis isozyme isoform X1 [KO:K00933] [EC:2.7.3.2]
118226883  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
118209072  ckmb; creatine kinase, muscle b [KO:K27382] [EC:2.7.3.2]
118235602  ckma; creatine kinase, muscle a [KO:K27382] [EC:2.7.3.2]
118218499  zgc:172076; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
118212076  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
118231992  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
118225739  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
118234221  ornithine decarboxylase-like isoform X1 [KO:K01581] [EC:4.1.1.17]
118208166  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
118235458  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
118229759  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
118226141  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
118228138  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
118235782  aldehyde dehydrogenase, dimeric NADP-preferring-like [KO:K00128] [EC:1.2.1.3]
118235783  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
118209883  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
118209884  aldehyde dehydrogenase family 3 member A2-like isoform X1 [KO:K00128] [EC:1.2.1.3]
118216667  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
118206355  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
118212077  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
118225547  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
118225539  cndp2; cytosolic non-specific dipeptidase [KO:K05604] [EC:3.4.13.20]
118234299  cytosolic non-specific dipeptidase-like [KO:K08660] [EC:3.4.13.18]
118231339  carnosine synthase 1-like isoform X1 [KO:K14755] [EC:6.3.2.11]
118222411  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
118234848  diamine acetyltransferase 1-like isoform X1 [KO:K00657] [EC:2.3.1.57]
118234849  diamine acetyltransferase 1-like [KO:K00657] [EC:2.3.1.57]
118234916  diamine acetyltransferase 2-like isoform X1 [KO:K00657] [EC:2.3.1.57]
118236631  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
118222203  amine oxidase [flavin-containing]-like [KO:K00274] [EC:1.4.3.4]
118222637  amine oxidase [flavin-containing]-like [KO:K00274] [EC:1.4.3.4]
118213078  si:ch211-127i16.2; probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
118214289  amine oxidase [flavin-containing]-like [KO:K00274] [EC:1.4.3.4]
118207856  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
118206631  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
118218855  arg1; arginase-1 isoform X1 [KO:K01476] [EC:3.5.3.1]
118214933  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
118218187  ornithine aminotransferase, mitochondrial-like isoform X1 [KO:K00819] [EC:2.6.1.13]
118221776  ornithine aminotransferase, mitochondrial-like [KO:K00819] [EC:2.6.1.13]
118216048  pyrroline-5-carboxylate reductase 1, mitochondrial-like [KO:K00286] [EC:1.5.1.2]
118219747  pycr1b; pyrroline-5-carboxylate reductase 1b [KO:K00286] [EC:1.5.1.2]
118226006  pycr3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
118212217  proline dehydrogenase 1, mitochondrial-like isoform X1 [KO:K00318] [EC:1.5.5.2]
118206847  prodhb; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
118211556  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
118221265  aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
118226919  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
118236313  prolyl 4-hydroxylase subunit alpha-2-like isoform X1 [KO:K00472] [EC:1.14.11.2]
118236314  prolyl 4-hydroxylase subunit alpha-2-like [KO:K00472] [EC:1.14.11.2]
118218419  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b isoform X1 [KO:K00472] [EC:1.14.11.2]
118218817  p4ha1a; prolyl 4-hydroxylase subunit alpha-1a isoform X1 [KO:K00472] [EC:1.14.11.2]
118209046  p4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
118220234  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
118206233  got1l1; putative aspartate aminotransferase, cytoplasmic 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
118218456  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
118221287  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
118227172  got2a; glutamic-oxaloacetic transaminase 2a, mitochondrial [KO:K14455] [EC:2.6.1.1]
118219744  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
118207055  D-amino-acid oxidase-like [KO:K00273] [EC:1.4.3.3]
118229933  trans-L-3-hydroxyproline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
aang00020  Citrate cycle (TCA cycle)
aang00220  Arginine biosynthesis
aang00250  Alanine, aspartate and glutamate metabolism
aang00260  Glycine, serine and threonine metabolism
aang00270  Cysteine and methionine metabolism
aang00310  Lysine degradation
aang00410  beta-Alanine metabolism
aang00470  D-Amino acid metabolism
aang00480  Glutathione metabolism
aang00630  Glyoxylate and dicarboxylate metabolism
aang00650  Butanoate metabolism
aang00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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