KEGG   PATHWAY: nmel00330
Entry
nmel00330                   Pathway                                
Name
Arginine and proline metabolism - Numida meleagris (helmeted guineafowl)
Class
Metabolism; Amino acid metabolism
Pathway map
nmel00330  Arginine and proline metabolism
nmel00330

Module
nmel_M00015  Proline biosynthesis, glutamate => proline [PATH:nmel00330]
nmel_M00047  Creatine pathway [PATH:nmel00330]
nmel_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:nmel00330]
nmel_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:nmel00330]
nmel_M00970  Proline degradation, proline => glutamate [PATH:nmel00330]
nmel_M00972  Proline metabolism [PATH:nmel00330]
Other DBs
GO: 0006525 0006560
Organism
Numida meleagris (helmeted guineafowl) [GN:nmel]
Gene
110404020  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
110388919  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
110390173  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
110401259  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
110403639  CKMT1A; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
110387261  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
110395498  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
110408594  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
110404540  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
110395394  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110390704  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
110397642  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
110406630  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
110407636  ALDH3A2; fatty aldehyde dehydrogenase isoform X1 [KO:K00128] [EC:1.2.1.3]
110389971  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
110402617  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
110394441  CNDP1; beta-Ala-His dipeptidase isoform X1 [KO:K05604] [EC:3.4.13.20]
110394204  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
110390570  carnosine synthase 1-like [KO:K14755] [EC:6.3.2.11]
110404480  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
110403719  amine oxidase [flavin-containing] B-like isoform X1 [KO:K00274] [EC:1.4.3.4]
110403733  amine oxidase [flavin-containing] A-like isoform X1 [KO:K00274] [EC:1.4.3.4]
110408510  AGMAT; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
110406170  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
110407551  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
110400739  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
110399980  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
110394050  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
110407304  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
110406451  proline dehydrogenase 1, mitochondrial-like [KO:K00318] [EC:1.5.5.2]
110408712  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
110399696  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
110398356  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
110392149  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
110400249  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
110405258  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
110400149  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
110404444  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
110400352  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
110406572  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
110401546  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
nmel00020  Citrate cycle (TCA cycle)
nmel00220  Arginine biosynthesis
nmel00250  Alanine, aspartate and glutamate metabolism
nmel00260  Glycine, serine and threonine metabolism
nmel00270  Cysteine and methionine metabolism
nmel00310  Lysine degradation
nmel00410  beta-Alanine metabolism
nmel00470  D-Amino acid metabolism
nmel00480  Glutathione metabolism
nmel00630  Glyoxylate and dicarboxylate metabolism
nmel00650  Butanoate metabolism
nmel00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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