KEGG   PATHWAY: onl05168
Entry
onl05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Oreochromis niloticus (Nile tilapia)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
onl05168  Herpes simplex virus 1 infection
onl05168

Organism
Oreochromis niloticus (Nile tilapia) [GN:onl]
Gene
102082145  tumor necrosis factor ligand superfamily member 14-like isoform X1 [KO:K05477]
102082760  tumor necrosis factor ligand superfamily member 14 [KO:K05477]
100708941  tumor necrosis factor receptor superfamily member 5 [KO:K05152]
100709475  tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K05152]
100703705  tumor necrosis factor receptor superfamily member 14 isoform X2 [KO:K05152]
102079249  uncharacterized protein LOC102079249 isoform X5 [KO:K05152]
100703972  tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
102082670  tumor necrosis factor receptor superfamily member 5 [KO:K05152]
100709212  tumor necrosis factor receptor superfamily member 5 isoform X2 [KO:K05152]
100689714  tumor necrosis factor receptor superfamily member 5-like isoform X2 [KO:K05152]
100697308  TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
100702092  traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
100708442  TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
100697176  TNF receptor-associated factor 5 isoform X1 [KO:K09849]
100698072  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
100692869  inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
100698148  inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
100703664  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
100691089  nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
100691708  NF-kappa-B inhibitor alpha [KO:K04734]
100702187  nfkb1; LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p105 subunit [KO:K02580]
100707676  rela; transcription factor p65 isoform X1 [KO:K04735]
100705328  inhibitor of apoptosis protein isoform X1 [KO:K16060]
102077886  poliovirus receptor [KO:K06081]
102078547  nectin-4 [KO:K06081]
109194321  nectin-4-like [KO:K06081]
100707450  nectin-1 isoform X1 [KO:K06081]
100699673  nectin1; nectin-1 isoform X1 [KO:K06081]
102077979  nectin-4-like isoform X1 [KO:K06081]
102079979  nectin-4 isoform X1 [KO:K06081]
112844122  poliovirus receptor-like [KO:K06081]
102079182  poliovirus receptor homolog isoform X1 [KO:K06081]
102080465  poliovirus receptor isoform X1 [KO:K06081]
112848122  nectin-4-like [KO:K06081]
102077830  nectin-4 [KO:K06081]
109196111  nectin-4 isoform X5 [KO:K06081]
102078979  nectin-2 isoform X1 [KO:K06081]
102079645  nectin-4 isoform X1 [KO:K06081]
102079940  poliovirus receptor homolog isoform X1 [KO:K06081]
102080174  nectin-3 isoform X1 [KO:K06081]
100707658  poliovirus receptor homolog isoform X1 [KO:K06531]
100711853  nectin-2 isoform X1 [KO:K06531]
100697902  ptpn11; tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
100700918  tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
100696606  integrin alpha-5 isoform X1 [KO:K06484]
100711983  integrin alpha-5 [KO:K06484]
100708604  itgb3; integrin beta-3 [KO:K06493]
100699105  integrin beta-3 isoform X1 [KO:K06493]
100690332  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
100692677  proto-oncogene tyrosine-protein kinase Src isoform X4 [KO:K05704] [EC:2.7.10.2]
100693670  syk; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
102078975  caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
100702954  interferon regulatory factor 3 [KO:K05411]
100702587  p53; cellular tumor antigen p53 isoform X1 [KO:K04451]
100700974  complement C3 [KO:K03990]
100691651  LOW QUALITY PROTEIN: complement C3 [KO:K03990]
100692186  complement C3 isoform X1 [KO:K03990]
100703748  c5; complement C5 [KO:K03994]
100708418  cfp; properdin [KO:K15412]
100694547  tlr2; toll-like receptor 2 [KO:K10159]
102077009  toll-like receptor 2 isoform X1 [KO:K10159]
102076284  LOW QUALITY PROTEIN: toll-like receptor 2 [KO:K10159]
109202487  toll-like receptor 2 [KO:K10159]
102076916  tlr2; toll-like receptor 2 [KO:K10159]
100705953  toll-like receptor 2 type-2 [KO:K10159]
100700534  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
100706192  irf7; interferon regulatory factor 7 [KO:K09447]
100703629  toll-like receptor 3 [KO:K05401]
100701239  TIR domain-containing adapter molecule 1 [KO:K05842]
100707440  irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
100703930  irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
100703551  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
100699877  mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
100689877  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X3 [KO:K04427] [EC:2.7.11.25]
100709656  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X3 [KO:K04403]
100700219  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
100707066  interleukin-1 beta [KO:K04519]
100707443  interleukin-1 beta [KO:K04519]
100693282  interleukin-1 beta [KO:K04519]
102077017  interleukin-6 [KO:K05405]
102081105  lymphotoxin-alpha isoform X2 [KO:K03156]
100534578  tnfb; tumor necrosis factor b (TNF superfamily, member 2) [KO:K03156]
100697746  tumor necrosis factor [KO:K03156]
100701404  interleukin-12 subunit alpha [KO:K05406]
100693748  interleukin-12 subunit alpha [KO:K05406]
100706746  interleukin-12 subunit beta [KO:K05425]
100695399  LOW QUALITY PROTEIN: interleukin-12 subunit beta [KO:K05425]
100690857  interleukin-12 subunit beta [KO:K05425]
100703536  ifih1; interferon-induced helicase C domain-containing protein 1 isoform X1 [KO:K12647] [EC:5.6.2.6]
100710322  mavs; mitochondrial antiviral-signaling protein [KO:K12648]
100702578  traf3; TNF receptor-associated factor 3 [KO:K03174]
100695544  ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
100711888  tbk1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
112847710  interferon a3-like [KO:K05414]
102083274  interferon a3 [KO:K05414]
100691561  interferon a3-like [KO:K05414]
109203135  interferon a3-like isoform X1 [KO:K05414]
109203155  interferon a3-like isoform X1 [KO:K05414]
100690759  interferon a3 isoform X1 [KO:K05414]
109203210  interferon a3 isoform X1 [KO:K05414]
109203208  interferon a3-like [KO:K05414]
100691025  interferon a3-like [KO:K05414]
112847709  interferon a3-like [KO:K05414]
112841720  interferon a3-like [KO:K05414]
109203266  interferon a3 isoform X1 [KO:K05414]
109203267  interferon a3-like isoform X1 [KO:K05414]
100691290  interferon a3 [KO:K05414]
100696424  interferon a3-like [KO:K05414]
100704886  interferon a3-like [KO:K05414]
100706412  interferon a3-like [KO:K05414]
109203209  interferon a3-like [KO:K05414]
102078106  cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
106097853  cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
109204785  cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
100697006  tmem173; stimulator of interferon genes protein [KO:K12654]
100692155  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100692170  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100691882  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
100706881  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
109196021  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
100689853  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
100708945  eif2ak1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
100691607  interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
100700343  interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
100691545  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
100704164  eif2ak4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
100696887  eif2s1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
100712493  eif2b1; translation initiation factor eIF-2B subunit alpha [KO:K03239]
100708663  eif2b2; translation initiation factor eIF-2B subunit beta [KO:K03754]
100709571  eif2b3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
100691675  eif2b4; translation initiation factor eIF-2B subunit delta [KO:K03680]
100697298  eif2b5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
100703662  host cell factor 1 isoform X1 [KO:K14966]
100695550  host cell factor 1 isoform X1 [KO:K14966]
100694816  hcfc2; host cell factor 2 isoform X1 [KO:K27390]
100690040  pou2f2; POU domain, class 2, transcription factor 2 isoform X2 [KO:K09364]
100695154  pou2f3; POU domain, class 2, transcription factor 3 isoform X1 [KO:K09364]
100708203  POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
100691666  pou2f1; POU domain, class 2, transcription factor 1 isoform X8 [KO:K09364]
102078673  interferon alpha/beta receptor 2 [KO:K05131]
100692065  interferon alpha/beta receptor 2 isoform X2 [KO:K05131]
100702554  socs3a; suppressor of cytokine signaling 3a [KO:K04696]
100704232  suppressor of cytokine signaling 3 [KO:K04696]
100690671  jak1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
100692332  tyk2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
100696359  stat1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
100709564  signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
100701534  signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11221]
100696509  irf9; interferon regulatory factor 9 isoform X1 [KO:K04693]
102076188  zinc finger protein 883 isoform X1 [KO:K09228]
102080068  zinc finger protein 345 isoform X1 [KO:K09228]
112846541  zinc finger protein 271-like [KO:K09228]
102081028  zinc finger protein 121 [KO:K09228]
102081628  zinc finger protein 420 [KO:K09228]
100699708  gastrula zinc finger protein XlCGF26.1 isoform X2 [KO:K09228]
102076594  zinc finger protein 250 [KO:K09228]
102079888  zinc finger protein 2 [KO:K09228]
109200302  zinc finger protein 121-like isoform X1 [KO:K09228]
112841622  zinc finger protein 11-like [KO:K09228]
102080469  zinc finger protein 2 [KO:K09228]
102083192  zinc finger protein 99-like [KO:K09228]
100695519  zinc finger protein 2 homolog isoform X1 [KO:K09228]
100695786  zinc finger protein 2 homolog isoform X1 [KO:K09228]
102079265  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
100692303  zinc finger protein 180 isoform X1 [KO:K09228]
106097637  zinc finger protein 271-like [KO:K09228]
102078101  zinc finger protein 708 isoform X1 [KO:K09228]
109200527  putative uncharacterized zinc finger protein 814 isoform X2 [KO:K09228]
109203667  zinc finger protein OZF [KO:K09228]
112843488  zinc finger protein 184-like [KO:K09228]
100697883  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
102081397  zinc finger protein 345 isoform X1 [KO:K09228]
102080440  gastrula zinc finger protein XlCGF26.1 isoform X3 [KO:K09228]
102079920  zinc finger protein 250 [KO:K09228]
100701940  zinc finger protein 729 [KO:K09228]
102076428  uncharacterized protein LOC102076428 [KO:K09228]
109201161  zinc finger protein 235-like isoform X1 [KO:K09228]
100693265  zinc finger protein 345 isoform X1 [KO:K09228]
102075971  zinc finger protein 729 isoform X1 [KO:K09228]
112847817  zinc finger protein 729-like [KO:K09228]
100699524  zinc finger protein 501 isoform X1 [KO:K09228]
109195406  uncharacterized protein LOC109195406 [KO:K09228]
102077170  zinc finger protein OZF [KO:K09228]
102079916  zinc finger protein 436 isoform X1 [KO:K09228]
100711268  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
112841726  oocyte zinc finger protein XlCOF6-like isoform X1 [KO:K09228]
100705896  zinc finger protein 2 homolog isoform X1 [KO:K09228]
102081460  zinc finger protein 235-like [KO:K09228]
109196585  zinc finger protein 99-like [KO:K09228]
112847859  zinc finger protein 665-like [KO:K09228]
112847881  zinc finger protein 721-like isoform X1 [KO:K09228]
112847882  zinc finger protein 595-like isoform X1 [KO:K09228]
112847915  zinc finger protein 665-like [KO:K09228]
106096688  zinc finger protein 729-like [KO:K09228]
112847938  zinc finger protein 708-like [KO:K09228]
112847941  zinc finger protein 721-like [KO:K09228]
112844887  zinc finger protein 708-like [KO:K09228]
100694627  zinc finger protein 239 isoform X2 [KO:K09228]
100710702  zinc finger protein 37 isoform X1 [KO:K09228]
106096933  oocyte zinc finger protein XlCOF6 isoform X1 [KO:K09228]
109195459  zinc finger and SCAN domain-containing protein 2 isoform X1 [KO:K09228]
112841690  zinc finger protein 501-like [KO:K09228]
106098952  zinc finger protein 436 isoform X1 [KO:K09228]
109201369  zinc finger protein 850-like [KO:K09228]
109201376  zinc finger protein 271-like [KO:K09228]
112846313  zinc finger protein 595-like [KO:K09228]
112847952  zinc finger protein 595-like [KO:K09228]
109203480  zinc finger protein 708-like [KO:K09228]
112847957  zinc finger protein 665-like [KO:K09228]
102078243  oocyte zinc finger protein XlCOF6 isoform X1 [KO:K09228]
109197587  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
109194563  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
109196860  zinc finger protein 99-like isoform X1 [KO:K09228]
102077972  zinc finger protein 665 [KO:K09228]
100703558  zinc finger protein 2 homolog [KO:K09228]
106097074  zinc finger protein 227 [KO:K09228]
102079997  zinc finger protein Xfin isoform X2 [KO:K09228]
100701877  zinc finger protein 260 isoform X1 [KO:K09228]
109195572  zinc finger protein OZF [KO:K09228]
109195575  zinc finger protein 135 [KO:K09228]
109195434  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
112846506  zinc finger protein 91-like [KO:K09228]
102079581  zinc finger protein 99-like [KO:K09228]
112846508  zinc finger protein 708-like [KO:K09228]
112846528  zinc finger protein 2 homolog [KO:K09228]
102076345  zinc finger protein OZF [KO:K09228]
100699804  zinc finger protein 883 isoform X2 [KO:K09228]
102083020  gastrula zinc finger protein XlCGF26.1 isoform X1 [KO:K09228]
109203498  zinc finger protein 664-like isoform X1 [KO:K09228]
102077854  zinc finger protein OZF [KO:K09228]
102076881  zinc finger protein 260 isoform X2 [KO:K09228]
100702763  zinc finger protein 708 [KO:K09228]
109197793  zinc finger protein 271 [KO:K09228]
109200328  zinc finger and SCAN domain-containing protein 2 isoform X1 [KO:K09228]
109203510  gastrula zinc finger protein XlCGF52.1 isoform X1 [KO:K09228]
100700874  zinc finger protein 2 homolog [KO:K09228]
100707319  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
102083182  gastrula zinc finger protein XlCGF26.1 isoform X1 [KO:K09228]
106097251  zinc finger and SCAN domain-containing protein 31 isoform X4 [KO:K09228]
112845603  zinc finger protein 271-like isoform X1 [KO:K09228]
100695089  zinc finger protein 391 [KO:K09228]
109200614  zinc finger protein 493 [KO:K09228]
102080237  zinc finger protein 37 isoform X1 [KO:K09228]
109203669  zinc finger protein 77 [KO:K09228]
112841743  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
106098120  zinc finger protein 660 [KO:K09228]
102081504  zinc finger protein 665 isoform X1 [KO:K09228]
102081668  endothelial zinc finger protein induced by tumor necrosis factor alpha isoform X1 [KO:K09228]
100710590  gastrula zinc finger protein xFG20-1 isoform X1 [KO:K09228]
100690414  zinc finger protein 37 homolog isoform X1 [KO:K09228]
106096685  zinc finger protein 420 isoform X1 [KO:K09228]
100706495  uncharacterized protein LOC100706495 [KO:K09228]
109200674  zinc finger protein 771 [KO:K09228]
100711400  zinc finger protein OZF [KO:K09228]
106098621  zinc finger protein 485 isoform X1 [KO:K09228]
112845985  zinc finger protein 883-like [KO:K09228]
112845994  zinc finger protein OZF-like [KO:K09228]
109201362  zinc finger protein 271-like [KO:K09228]
100709885  zinc finger protein 14 [KO:K09228]
100694247  zinc finger protein OZF [KO:K09228]
100699968  zinc finger protein 665 isoform X1 [KO:K09228]
106098460  zinc finger protein 37 [KO:K09228]
106097435  zinc finger protein 239-like [KO:K09228]
100690930  oocyte zinc finger protein XlCOF6.1 [KO:K09228]
100694456  zinc finger protein 260 isoform X1 [KO:K09228]
102080698  zinc finger protein 14 isoform X1 [KO:K09228]
100694192  zinc finger protein 391 isoform X1 [KO:K09228]
102078572  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
106098477  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112843845  zinc finger protein 431-like [KO:K09228]
102076097  zinc finger and SCAN domain-containing protein 2 isoform X5 [KO:K09228]
102075738  zinc finger protein 91 isoform X1 [KO:K09228]
100694564  zinc finger protein 664 isoform X1 [KO:K09228]
100698008  zinc finger protein OZF [KO:K09228]
102080542  zinc finger protein 595-like [KO:K09228]
100711962  zinc finger protein OZF-like isoform X1 [KO:K09228]
100700328  zinc finger protein 260 [KO:K09228]
102082686  zinc finger protein 184 [KO:K09228]
102080905  zinc finger protein 260 isoform X1 [KO:K09228]
100694110  zinc finger protein 436 isoform X1 [KO:K09228]
100709547  gastrula zinc finger protein XlCGF26.1 isoform X1 [KO:K09228]
102080278  gastrula zinc finger protein XlCGF26.1 isoform X2 [KO:K09228]
102081041  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
109196781  zinc finger protein 347-like [KO:K09228]
112846306  zinc finger protein 726-like [KO:K09228]
112847886  zinc finger protein 678-like [KO:K09228]
106096689  zinc finger protein 726-like [KO:K09228]
102079992  uncharacterized protein LOC102079992 isoform X1 [KO:K09228]
102079088  zinc finger protein 525 [KO:K09228]
102077488  zinc finger protein 471 isoform X1 [KO:K09228]
100695441  zinc finger protein OZF isoform X1 [KO:K09228]
109194524  zinc finger protein 260-like isoform X2 [KO:K09228]
100698278  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
109196898  zinc finger protein 883-like isoform X1 [KO:K09228]
109199366  zinc finger protein 14-like [KO:K09228]
109201442  zinc finger protein 99-like [KO:K09228]
109194485  zinc finger protein 2-like isoform X1 [KO:K09228]
112847951  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
100696676  zinc finger protein 501 [KO:K09228]
109195617  gastrula zinc finger protein XlCGF8.2DB-like [KO:K09228]
106097167  zinc finger protein 665-like [KO:K09228]
102083228  zinc finger protein 2 isoform X1 [KO:K09228]
102077355  zinc finger protein 544 [KO:K09228]
100710048  zinc finger protein 501 [KO:K09228]
102079854  zinc finger protein OZF-like [KO:K09228]
102079942  oocyte zinc finger protein XlCOF20 [KO:K09228]
100704393  zinc finger protein OZF isoform X5 [KO:K09228]
102078639  zinc finger protein 3 isoform X1 [KO:K09228]
102079609  zinc finger and SCAN domain-containing protein 31-like isoform X3 [KO:K09228]
102081078  zinc finger protein 271 [KO:K09228]
102080097  zinc finger protein Xfin [KO:K09228]
102080341  zinc finger protein 2 homolog [KO:K09228]
100702488  zinc finger protein 397 [KO:K09228]
102082333  zinc finger protein 250 isoform X1 [KO:K09228]
100711392  zinc finger protein 271 isoform X1 [KO:K09228]
100710859  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
109203181  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
109203184  zinc finger protein 37 [KO:K09228]
100697744  zinc finger protein 883 [KO:K09228]
109195431  zinc finger protein 665-like [KO:K09228]
100695994  zinc finger protein 345 [KO:K09228]
106099028  gastrula zinc finger protein XlCGF46.1 [KO:K09228]
100701582  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
102080177  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
100706509  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
100706246  zinc finger protein 271 isoform X1 [KO:K09228]
109197593  zinc finger protein 616-like isoform X1 [KO:K09228]
109194461  zinc finger protein OZF isoform X1 [KO:K09228]
102076612  zinc finger protein OZF [KO:K09228]
100691464  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
100691195  zinc finger and SCAN domain-containing protein 12 [KO:K09228]
109196101  zinc finger protein 271-like [KO:K09228]
109203538  zinc finger protein 347 [KO:K09228]
102079115  uncharacterized protein LOC102079115 isoform X3 [KO:K09228]
102080800  zinc finger protein 37 [KO:K09228]
102081738  zinc finger protein 397 [KO:K09228]
100697682  zinc finger protein 260 isoform X1 [KO:K09228]
102077529  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
100690512  ifngr1l; interferon gamma receptor 1-like precursor [KO:K05132]
102081538  ifngr1; interferon gamma receptor 1 precursor [KO:K05132]
109194437  ifngr2-2; uncharacterized protein ifngr2-2 [KO:K05133]
100692564  tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
100710044  tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
100700970  daxx; death domain-associated protein 6 isoform X1 [KO:K02308]
100701175  tap1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
100698679  antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
100696572  antigen peptide transporter 2-like [KO:K05654] [EC:7.4.2.14]
100701247  tapasin [KO:K08058]
100707709  protein disulfide-isomerase A3 isoform X2 [KO:K08056] [EC:5.3.4.1]
100706685  pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
100701980  calreticulin [KO:K08057]
100711757  calreticulin [KO:K08057]
100704618  calreticulin [KO:K08057]
100704307  H-2 class I histocompatibility antigen, Q10 alpha chain [KO:K06751]
100704575  H-2 class I histocompatibility antigen, L-D alpha chain isoform X1 [KO:K06751]
100690589  major histocompatibility complex class I-related gene protein [KO:K06751]
100693013  major histocompatibility complex class I-related gene protein [KO:K06751]
109200342  HLA class I histocompatibility antigen, B-53 alpha chain [KO:K06751]
109200348  HLA class I histocompatibility antigen, B-53 alpha chain-like [KO:K06751]
109194531  class I histocompatibility antigen, F10 alpha chain-like [KO:K06751]
100704472  H-2 class I histocompatibility antigen, Q9 alpha chain [KO:K06751]
109194569  class I histocompatibility antigen, F10 alpha chain-like [KO:K06751]
112841703  major histocompatibility complex class I-related gene protein-like isoform X1 [KO:K06751]
112843554  class I histocompatibility antigen, F10 alpha chain-like [KO:K06751]
100702595  LOW QUALITY PROTEIN: class I histocompatibility antigen, F10 alpha chain [KO:K06751]
100702241  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
100701791  class I histocompatibility antigen, F10 alpha chain [KO:K06751]
100698385  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
102076922  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
102075777  LOW QUALITY PROTEIN: DLA class I histocompatibility antigen, A9/A9 alpha chain [KO:K06751]
109198656  H-2 class I histocompatibility antigen, L-D alpha chain-like [KO:K06751]
112841710  class I histocompatibility antigen, F10 alpha chain-like [KO:K06751]
109201079  HLA class I histocompatibility antigen, B-53 alpha chain-like [KO:K06751]
112846215  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100689711  class I histocompatibility antigen, F10 alpha chain isoform X2 [KO:K06751]
109196810  H-2 class I histocompatibility antigen, L-D alpha chain-like [KO:K06751]
109196813  H-2 class I histocompatibility antigen, L-D alpha chain-like [KO:K06751]
100699631  LOW QUALITY PROTEIN: class I histocompatibility antigen, F10 alpha chain [KO:K06751]
109200724  LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
109199964  major histocompatibility complex class I-related gene protein-like [KO:K06751]
106096465  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
100697852  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
100702327  class I histocompatibility antigen, F10 alpha chain [KO:K06751]
109200123  class I histocompatibility antigen, F10 alpha chain [KO:K06751]
100698118  uncharacterized protein LOC100698118 isoform X2 [KO:K06751]
106098985  H-2 class I histocompatibility antigen, L-D alpha chain-like [KO:K06751]
100696765  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
102076776  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
102077098  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100692201  major histocompatibility complex class I-related gene protein isoform X2 [KO:K06751]
100692471  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
109196360  major histocompatibility complex class I-related gene protein [KO:K06751]
100701504  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
109196367  major histocompatibility complex class I-related gene protein-like [KO:K06751]
109196370  major histocompatibility complex class I-related gene protein-like [KO:K06751]
109196374  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100711084  major histocompatibility complex class I-related gene protein [KO:K06751]
102078978  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
100711353  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100691933  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
100700419  major histocompatibility complex class I-related gene protein-like isoform X1 [KO:K06751]
109194594  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100690863  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
100699341  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
102082902  major histocompatibility complex class I-related gene protein [KO:K06751]
100711894  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100712435  major histocompatibility complex class I-related gene protein [KO:K06751]
112841688  hereditary hemochromatosis protein homolog [KO:K06751]
102079388  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
100708586  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100699614  major histocompatibility complex class I-related gene protein-like [KO:K06751]
109196375  major histocompatibility complex class I-related gene protein-like [KO:K06751]
100703933  major histocompatibility complex class I-related gene protein-like [KO:K06751]
102079144  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
102080229  major histocompatibility complex class I-related gene protein [KO:K06751]
100699073  major histocompatibility complex class I-related gene protein [KO:K06751]
100697370  beta-2-microglobulin [KO:K08055]
100698172  beta-2-microglobulin [KO:K08055]
100692549  H-2 class II histocompatibility antigen, A-U alpha chain isoform X1 [KO:K06752]
109194340  H-2 class II histocompatibility antigen, A-U alpha chain isoform X1 [KO:K06752]
109201613  H-2 class II histocompatibility antigen, E-S beta chain [KO:K06752]
100702234  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
109204230  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
106098650  DLA class II histocompatibility antigen, DR-1 beta chain [KO:K06752]
100691970  orni-dba; mamu class II histocompatibility antigen, DR alpha chain-like precursor [KO:K06752]
100703853  HLA class II histocompatibility antigen, DRB1-8 beta chain [KO:K06752]
109194176  H-2 class II histocompatibility antigen, E-S beta chain-like [KO:K06752]
100701242  H-2 class II histocompatibility antigen, E-S beta chain isoform X1 [KO:K06752]
100701693  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
100701969  H-2 class II histocompatibility antigen, E-S beta chain [KO:K06752]
100703581  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
102082262  H-2 class II histocompatibility antigen, E-S beta chain isoform X1 [KO:K06752]
100698680  RLA class II histocompatibility antigen, DP alpha-1 chain [KO:K06752]
109195038  class II histocompatibility antigen, B-L beta chain [KO:K06752]
106096967  class II histocompatibility antigen, B-L beta chain [KO:K06752]
109195039  H-2 class II histocompatibility antigen, A-F alpha chain [KO:K06752]
109196430  H-2 class II histocompatibility antigen, A-U alpha chain isoform X1 [KO:K06752]
100710202  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
100690666  HLA class II histocompatibility antigen, DRB1-8 beta chain-like [KO:K06752]
100699091  H-2 class II histocompatibility antigen, E-S beta chain isoform X1 [KO:K06752]
112841757  RLA class II histocompatibility antigen, DP alpha-1 chain-like [KO:K06752]
100709109  H-2 class II histocompatibility antigen, E-S beta chain isoform X1 [KO:K06752]
100710185  RLA class II histocompatibility antigen, DP alpha-1 chain isoform X1 [KO:K06752]
100709378  RLA class II histocompatibility antigen, DP alpha-1 chain-like [KO:K06752]
100710179  H-2 class II histocompatibility antigen, E-S beta chain-like isoform X1 [KO:K06752]
100710971  RLA class II histocompatibility antigen, DP alpha-1 chain isoform X3 [KO:K06752]
100701975  H-2 class II histocompatibility antigen, E-S beta chain isoform X1 [KO:K06752]
100708205  H-2 class II histocompatibility antigen, E-S beta chain [KO:K06752]
100693481  H-2 class II histocompatibility antigen, A-U alpha chain isoform X1 [KO:K06752]
100705515  RLA class II histocompatibility antigen, DP alpha-1 chain [KO:K06752]
100702826  H-2 class II histocompatibility antigen, E-S beta chain-like isoform X2 [KO:K06752]
109201948  rano class II histocompatibility antigen, A beta chain-like isoform X1 [KO:K06752]
109201950  H-2 class II histocompatibility antigen, A-Q alpha chain-like [KO:K06752]
100706040  LOW QUALITY PROTEIN: mamu class II histocompatibility antigen, DR alpha chain-like [KO:K06752]
109204231  rano class II histocompatibility antigen, A beta chain [KO:K06752]
109194343  DLA class II histocompatibility antigen, DR-1 beta chain isoform X1 [KO:K06752]
100709279  mamu class II histocompatibility antigen, DR alpha chain-like [KO:K06752]
100690392  RLA class II histocompatibility antigen, DP alpha-1 chain [KO:K06752]
100628564  MHC class II beta chain [KO:K06752]
100692238  patr class I histocompatibility antigen, B-1 alpha chain isoform X1 [KO:K06752]
100711901  H-2 class II histocompatibility antigen, E-S beta chain [KO:K06752]
100697318  RLA class II histocompatibility antigen, DP alpha-1 chain [KO:K06752]
109202867  HLA class II histocompatibility antigen, DRB1-8 beta chain-like [KO:K06752]
109204294  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
100691149  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
100692000  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
100702693  H-2 class II histocompatibility antigen, A-U alpha chain isoform X1 [KO:K06752]
100692508  RLA class II histocompatibility antigen, DP alpha-1 chain isoform X1 [KO:K06752]
109194454  rano class II histocompatibility antigen, A beta chain-like isoform X1 [KO:K06752]
102082498  rano class II histocompatibility antigen, A beta chain isoform X1 [KO:K06752]
100709634  cd74; HLA class II histocompatibility antigen gamma chain [KO:K06505]
100704479  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100707861  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100706609  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100705849  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
100691322  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
100693657  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
100710015  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100709733  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
100691647  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100708273  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
100690473  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X5 [KO:K02649]
100707971  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100705233  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100692017  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100702193  RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100691860  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100705892  hamartin isoform X1 [KO:K07206]
100704495  hamartin [KO:K07206]
100696216  tsc2; tuberin isoform X2 [KO:K07207]
100699213  rheb; GTP-binding protein Rheb [KO:K07208]
100700986  GTP-binding protein Rheb [KO:K07208]
100700382  mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
100704901  eukaryotic translation initiation factor 4E-binding protein 1 isoform X1 [KO:K07205]
100692160  eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
100692146  SRSF protein kinase 1 isoform X2 [KO:K15409] [EC:2.7.11.1]
100701465  srpk1; SRSF protein kinase 1 isoform X1 [KO:K15409] [EC:2.7.11.1]
100692325  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 1 [KO:K12890]
100704524  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 1B [KO:K12890]
100705065  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 1 [KO:K12890]
100695205  serine/arginine-rich splicing factor 2 isoform X1 [KO:K12891]
100710640  serine/arginine-rich splicing factor 2 [KO:K12891]
100711756  serine/arginine-rich splicing factor 3 [KO:K12892]
100692059  srsf3; serine/arginine-rich splicing factor 3 [KO:K12892]
100695830  srsf5; serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
100690725  srsf6; serine/arginine-rich splicing factor 6 isoform X1 [KO:K12893]
100690823  serine/arginine-rich splicing factor 6 isoform X1 [KO:K12893]
100707620  serine/arginine-rich splicing factor 5 [KO:K12893]
100690923  serine/arginine-rich splicing factor 4 isoform X1 [KO:K12893]
100708809  srsf7; serine/arginine-rich splicing factor 7 isoform X2 [KO:K12896]
100707309  serine/arginine-rich splicing factor 9 isoform X2 [KO:K21123]
100704151  nxf1; nuclear RNA export factor 1 isoform X1 [KO:K14284]
100707310  alyref; THO complex subunit 4 [KO:K12881]
100709252  THO complex subunit 4 [KO:K12881]
100703882  cd40lg; CD40 ligand [KO:K04389]
100705827  tumor necrosis factor ligand superfamily member 6 [KO:K04389]
102083126  tumor necrosis factor receptor superfamily member 6 [KO:K04390]
100705695  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
102080840  tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
100707974  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
100706963  fadd; FAS-associated death domain protein [KO:K02373]
100702676  caspase-8 [KO:K04398] [EC:3.4.22.61]
100702139  caspase-8 [KO:K04398] [EC:3.4.22.61]
102079913  caspase-8 [KO:K04398] [EC:3.4.22.61]
109194206  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
100699927  uncharacterized protein LOC100699927 [KO:K04726]
106097998  apoptosis regulator BAX [KO:K02159]
109201890  apoptosis regulator BAX [KO:K02159]
100706164  apoptosis regulator BAX [KO:K02159]
100712130  bad; bcl2-associated agonist of cell death [KO:K02158]
100710191  bcl2; apoptosis regulator Bcl-2 [KO:K02161]
102079353  apoptosis regulator Bcl-2 [KO:K02161]
100704382  bcl2l1; bcl-2-like protein 1 [KO:K04570]
100700270  bcl-2-like protein 1 [KO:K04570]
100692041  cytochrome c isoform X3 [KO:K08738]
100693973  LOW QUALITY PROTEIN: cytochrome c-a-like [KO:K08738]
100696271  cytochrome c-b [KO:K08738]
100701636  apaf1; apoptotic protease-activating factor 1 [KO:K02084]
100700134  casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
100695417  caspase-3 [KO:K02187] [EC:3.4.22.56]
100695678  caspase-3 [KO:K02187] [EC:3.4.22.56]
100534438  casp3a; caspase 3, apoptosis-related cysteine peptidase a [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
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Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
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Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
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MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
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PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
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Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
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Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
PMID:15056211
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
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Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
PMID:12855695
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
PMID:24262390
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
PMID:26952111
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
PMID:21994567
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
PMID:15276609
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
  Journal
Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
PMID:29298887
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
PMID:19344302
  Authors
Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
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Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
PMID:23115300
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
  Journal
J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
PMID:17229694
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
Reference
PMID:12826401
  Authors
Wysocka J, Herr W
  Title
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
  Journal
Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
Reference
PMID:27367734
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
  Journal
Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
Reference
PMID:15163721
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
Reference
PMID:23864622
  Authors
Gu H, Zheng Y, Roizman B
  Title
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
  Journal
J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
Reference
PMID:21994592
  Authors
Tavalai N, Stamminger T
  Title
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
  Journal
Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
Reference
PMID:21146386
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Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
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Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:12960333
  Authors
Neumann J, Eis-Hubinger AM, Koch N
  Title
Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
  Journal
J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
Reference
PMID:25798530
  Authors
Liu X, Cohen JI
  Title
The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
  Journal
Virology 479-480:568-77 (2015)
DOI:10.1016/j.virol.2015.02.040
Reference
PMID:28468873
  Authors
Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
  Journal
J Virol 91:e00295-17 (2017)
DOI:10.1128/JVI.00295-17
Reference
PMID:18508584
  Authors
Sandri-Goldin RM
  Title
The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
  Journal
Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
Reference
PMID:15078920
  Authors
Sandri-Goldin RM
  Title
Viral regulation of mRNA export.
  Journal
J Virol 78:4389-96 (2004)
DOI:10.1128/JVI.78.9.4389-4396.2004
Reference
PMID:27154074
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
onl03040  Spliceosome
onl03050  Proteasome
onl04115  p53 signaling pathway
onl04210  Apoptosis
onl04620  Toll-like receptor signaling pathway
onl04622  RIG-I-like receptor signaling pathway
KO pathway
ko05168   
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