KEGG   PATHWAY: rde00630
Entry
rde00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Roseobacter denitrificans
Class
Metabolism; Carbohydrate metabolism
Pathway map
rde00630  Glyoxylate and dicarboxylate metabolism
rde00630

Module
rde_M00373  Ethylmalonyl pathway [PATH:rde00630]
rde_M00621  Glycine cleavage system [PATH:rde00630]
rde_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rde00630]
Other DBs
GO: 0046487 0043648
Organism
Roseobacter denitrificans [GN:rde]
Gene
RD1_2332  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RD1_1117  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RD1_3325  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
RD1_1617  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RD1_3219  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
RD1_2555  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
RD1_4246  mtkB; malate-CoA ligase, alpha subunit, putative [KO:K08692] [EC:6.2.1.9]
RD1_1163  mtkB; Malate-CoA ligase, alpha subunit, putative [KO:K08692] [EC:6.2.1.9]
RD1_1162  mtkA; malate-CoA ligase, beta subunit, putative [KO:K14067] [EC:6.2.1.9]
RD1_0201  bktB; beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
RD1_3394  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RD1_0025  thiolase, N-terminal domain [KO:K00626] [EC:2.3.1.9]
RD1_3972  fadA; fatty acid oxidation complex beta subunit [KO:K00626] [EC:2.3.1.9]
RD1_3395  phbB; acetoacetyl-CoA reductase, putative [KO:K00023] [EC:1.1.1.36]
RD1_3522  MaoC-like protein, putative [KO:K17865] [EC:4.2.1.55]
RD1_0507  MaoC-like protein, putative [KO:K17865] [EC:4.2.1.55]
RD1_1637  ccrA; crotonyl-CoA reductase, putative [KO:K14446] [EC:1.3.1.85]
RD1_1179  conserved hypothetical protein [KO:K05606] [EC:5.1.99.1]
RD1_1635  mutB; methylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
RD1_1372  ibd2; isobutyryl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
RD1_1623  MaoC family protein [KO:K14449] [EC:4.2.1.148]
RD1_4242  mclA; malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
RD1_1160  mclA; malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
RD1_1001  citE; citrate lyase, beta subunit, putative [KO:K08691] [EC:4.1.3.24 4.1.3.25]
RD1_1620  citE; citrate lyase, beta subunit, putative [KO:K14451] [EC:3.1.2.30]
RD1_2032  pccA; propionyl-CoA carboxylase, alpha subunit [KO:K01965] [EC:6.4.1.3]
RD1_2028  pccB; propionyl-CoA carboxylase, beta subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
RD1_2035  mutA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
RD1_0625  glcD; glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
RD1_0626  glcE; glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
RD1_0627  glcF; glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
RD1_3437  gyaR; glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
RD1_1204  2-hydroxyacid dehydrogenase, putative [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RD1_1442  hydrolase, putative [KO:K01091] [EC:3.1.3.18]
RD1_2529  haloacid dehalogenase-like hydrolase, putative [KO:K01091] [EC:3.1.3.18]
RD1_3303  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
RD1_3476  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
RD1_1750  sgaA; serine--glyoxylate aminotransferase, putative [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RD1_2892  sgaA; serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RD1_1497  glutamine synthetase, putative [KO:K01915] [EC:6.3.1.2]
RD1_1894  glutamine synthetase, putative [KO:K01915] [EC:6.3.1.2]
RD1_1892  glutamine synthetase, putative [KO:K01915] [EC:6.3.1.2]
RD1_2173  ipuC; gamma-glutamylisopropylamide synthetase, putative [KO:K01915] [EC:6.3.1.2]
RD1_2569  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
RD1_3991  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RD1_4249  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RD1_1165  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RD1_1225  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
RD1_0003  aminomethyltransferase, putative [KO:K00605] [EC:2.1.2.10]
RD1_1222  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
RD1_3858  glycine cleavage T-protein (aminomethyl transferase) family protein [KO:K00605] [EC:2.1.2.10]
RD1_1603  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
RD1_2995  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
RD1_3670  pyridine nucleotide-disulfide oxidoreductase, putative [KO:K00382] [EC:1.8.1.4]
RD1_1223  gcvH; glycine cleavage system H protein [KO:K02437]
RD1_0684  glxR; 2-hydroxy-3-oxopropionate reductase, putative [KO:K00042] [EC:1.1.1.60]
RD1_4241  hydroxypyruvate reductase, putative [KO:K11529] [EC:2.7.1.165]
RD1_1981  ttuD; hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
RD1_2878  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RD1_4234  fdhA; formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
RD1_2897  fdhA; formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
RD1_4233  fdhB; formate dehydrogenase, beta subunit [KO:K22515] [EC:1.17.1.9]
RD1_2896  fdhB; formate dehydrogenase Fe-S subunit [KO:K00124]
RD1_2895  fdhI; formate dehydrogenase, gamma subunit, putative [KO:K00127]
RD1_3602  fmdA; amidase [KO:K01455] [EC:3.5.1.49]
RD1_3679  hutG; N-formylglutamate amidohydrolase, putative [KO:K01458] [EC:3.5.1.68]
RD1_2061  n-formylglutamate amidohydrolase, putative [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
rde00010  Glycolysis / Gluconeogenesis
rde00020  Citrate cycle (TCA cycle)
rde00030  Pentose phosphate pathway
rde00053  Ascorbate and aldarate metabolism
rde00071  Fatty acid degradation
rde00230  Purine metabolism
rde00250  Alanine, aspartate and glutamate metabolism
rde00260  Glycine, serine and threonine metabolism
rde00620  Pyruvate metabolism
rde00710  Carbon fixation by Calvin cycle
rde00750  Vitamin B6 metabolism
rde00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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