KEGG   PATHWAY: sbq04714
Entry
sbq04714                    Pathway                                
Name
Thermogenesis - Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Description
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological function under conditions of environmental challenge. Thermogenesis in brown and beige adipose tissue is mainly controlled by norepinephrine, which is released from sympathetic nervous system in response to cold or dietary stimuli. The mitochondrial uncoupling protein 1 (UCP1) is responsible for the process whereby chemical energy is converted into heat in these adipocytes. Activation of these adipocytes leads to an increase in calorie consumption and is expected to improve overweight conditions, providing a potential strategy for treating obesity and its related metabolic disorders.
Class
Organismal Systems; Environmental adaptation
Pathway map
sbq04714  Thermogenesis
sbq04714

Other DBs
GO: 1990845
Organism
Saimiri boliviensis boliviensis (Bolivian squirrel monkey) [GN:sbq]
Gene
101029188  ADRB3; LOW QUALITY PROTEIN: beta-3 adrenergic receptor [KO:K04143]
101043452  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
104652116  neuroendocrine secretory protein 55 [KO:K04632]
101027981  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
101043334  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
101040601  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
101044688  ADCY4; adenylate cyclase type 4 isoform X2 [KO:K08044] [EC:4.6.1.1]
101049747  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
101037803  ADCY6; adenylate cyclase type 6 isoform X2 [KO:K08046] [EC:4.6.1.1]
101032672  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
101034552  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
101052034  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
101048632  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
101034152  cAMP-dependent protein kinase catalytic subunit gamma-like [KO:K04345] [EC:2.7.11.11]
101036705  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
101043989  PRKACG; cAMP-dependent protein kinase catalytic subunit gamma isoform X1 [KO:K04345] [EC:2.7.11.11]
101047300  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
101034085  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
101042795  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
101044974  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
101036473  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
101052885  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
101041199  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X4 [KO:K09048]
101054090  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
101028887  PRDM16; PR domain zinc finger protein 16 [KO:K22410] [EC:2.1.1.367]
101052328  ZNF516; zinc finger protein 516 [KO:K22411]
101034653  KDM1A; lysine-specific histone demethylase 1A isoform X1 [KO:K11450] [EC:1.14.99.66]
101044613  UCP1; mitochondrial brown fat uncoupling protein 1 [KO:K08769]
101036878  KDM3B; lysine-specific demethylase 3B [KO:K15601] [EC:1.14.11.65]
101048409  KDM3A; lysine-specific demethylase 3A [KO:K15601] [EC:1.14.11.65]
101052445  SMARCA4; transcription activator BRG1 [KO:K11647] [EC:5.6.2.-]
101035707  SMARCA2; probable global transcription activator SNF2L2 isoform X1 [KO:K11647] [EC:5.6.2.-]
101037648  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
101040225  SMARCC1; SWI/SNF complex subunit SMARCC1 [KO:K11649]
101028240  SMARCC2; SWI/SNF complex subunit SMARCC2 [KO:K11649]
101029512  SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X2 [KO:K11650]
101041234  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1 [KO:K11650]
101038519  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [KO:K11650]
101033768  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 [KO:K11651]
101037287  ACTB; actin, cytoplasmic 1 [KO:K05692]
101050060  actin, cytoplasmic 2-like isoform X1 [KO:K05692]
101049910  ACTG1; actin, cytoplasmic 2 [KO:K05692]
104651678  actin, cytoplasmic 1-like [KO:K05692]
101034204  ACTL6A; LOW QUALITY PROTEIN: actin-like protein 6A [KO:K11340]
101051206  ACTL6B; actin-like protein 6B isoform X1 [KO:K11652]
101044635  ARID1B; AT-rich interactive domain-containing protein 1B isoform X6 [KO:K11653]
101037097  ARID1A; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
101038484  DPF1; zinc finger protein neuro-d4 [KO:K22198]
101052635  DPF3; zinc finger protein DPF3 isoform X1 [KO:K22198]
101028278  PPARG; peroxisome proliferator-activated receptor gamma [KO:K08530]
101034123  MAP3K5; mitogen-activated protein kinase kinase kinase 5 [KO:K04426] [EC:2.7.11.25]
101034633  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X2 [KO:K04432] [EC:2.7.12.2]
101037444  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
101044137  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
101040899  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
101052690  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
101046514  PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X2 [KO:K07202]
101035834  ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
101037109  SIRT6; NAD-dependent protein deacetylase sirtuin-6 isoform X2 [KO:K11416] [EC:2.3.1.286]
101048392  FGF21; fibroblast growth factor 21 [KO:K22429]
101039003  PLIN1; perilipin-1 [KO:K08768]
101052652  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
101033046  PNPLA2; patatin-like phospholipase domain-containing protein 2 [KO:K16816] [EC:3.1.1.3]
101037361  MGLL; monoglyceride lipase isoform X4 [KO:K01054] [EC:3.1.1.23]
101030830  PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2 [KO:K07198] [EC:2.7.11.31]
101033212  PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 [KO:K07198] [EC:2.7.11.31]
101029046  PRKAB1; 5'-AMP-activated protein kinase subunit beta-1 [KO:K07199]
101051388  PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 [KO:K07199]
101028682  PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3 isoform X1 [KO:K07200]
101044457  PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1 [KO:K07200]
101042380  PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 [KO:K07200]
101041383  GCG; glucagon [KO:K05259]
101033727  BMP8A; bone morphogenetic protein 8A [KO:K16622]
101053389  CNR1; cannabinoid receptor 1 [KO:K04277]
101042923  NPPA; natriuretic peptides A [KO:K12334]
101042618  NPPB; natriuretic peptides B [KO:K12335]
101044584  NPR1; atrial natriuretic peptide receptor 1 isoform X2 [KO:K12323] [EC:4.6.1.2]
101043597  PRKG1; cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
101033123  PRKG2; cGMP-dependent protein kinase 2 isoform X1 [KO:K19477] [EC:2.7.11.12]
101035459  KLB; beta-klotho [KO:K22404]
101033213  FGFR1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
101043538  FRS2; fibroblast growth factor receptor substrate 2 [KO:K12461]
101038666  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
101036943  SOS1; son of sevenless homolog 1 [KO:K03099]
101046427  SOS2; son of sevenless homolog 2 [KO:K03099]
101047663  HRAS; GTPase HRas isoform X2 [KO:K02833]
101047035  KRAS; GTPase KRas isoform X1 [KO:K07827]
101036877  NRAS; GTPase NRas [KO:K07828]
101045905  RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
101047213  RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
101045276  ribosomal protein S6 kinase alpha-2 [KO:K04373] [EC:2.7.11.1]
101035085  RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
101028002  TSC1; hamartin isoform X1 [KO:K07206]
101031475  TSC2; tuberin isoform X5 [KO:K07207]
101039601  RPTOR; regulatory-associated protein of mTOR [KO:K07204]
101047083  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
101028510  MLST8; target of rapamycin complex subunit LST8 isoform X1 [KO:K08266]
101035426  AKT1S1; proline-rich AKT1 substrate 1 isoform X2 [KO:K16184]
101033758  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
101038541  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
101038852  RPS6; 40S ribosomal protein S6 [KO:K02991]
101031622  ACSL5; LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase 5 [KO:K01897] [EC:6.2.1.3]
101041309  ACSL3; long-chain-fatty-acid--CoA ligase 3 [KO:K01897] [EC:6.2.1.3]
101028636  ACSL1; long-chain-fatty-acid--CoA ligase 1 isoform X2 [KO:K01897] [EC:6.2.1.3]
101044212  ACSL6; long-chain-fatty-acid--CoA ligase 6 isoform X1 [KO:K01897] [EC:6.2.1.3]
101033719  ACSL4; long-chain-fatty-acid--CoA ligase 4 isoform X2 [KO:K01897] [EC:6.2.1.3]
13228911  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
13228912  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
13228918  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
13228910  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
13228919  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
13228907  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
13228908  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
101037033  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
101049213  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
101031505  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:7.1.1.2]
101039247  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
101044441  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
101047065  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
101027656  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1 [KO:K03940] [EC:7.1.1.2]
101027721  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
101047545  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:7.1.1.2]
101044354  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
101035145  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
101053450  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
101052501  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 isoform X2 [KO:K03946]
101030840  NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
101035938  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
101031560  NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
101039979  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like isoform X1 [KO:K03949]
101027595  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
101035220  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like isoform X1 [KO:K03949]
104653297  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like isoform X1 [KO:K03949]
104652594  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like [KO:K03949]
101051623  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
101038075  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
101035659  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
101028201  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
101028433  NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
101035902  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
101030516  acyl carrier protein, mitochondrial-like [KO:K03955]
101047198  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
101044072  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
101047340  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
101051290  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial isoform X1 [KO:K03958]
101039525  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial-like [KO:K03958]
101029660  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
101048990  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
101034513  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
101044891  NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 isoform X2 [KO:K03962]
101033565  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
104650487  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform X1 [KO:K03964]
101028411  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
101034007  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
101039653  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
101035051  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
101051211  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
101041764  NDUFAF1; complex I intermediate-associated protein 30, mitochondrial [KO:K18159]
101047126  NDUFAF2; mimitin, mitochondrial [KO:K18160]
101030355  NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 [KO:K09008]
101047967  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4-like [KO:K18161]
101040733  NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [KO:K18161]
101039392  NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [KO:K18162] [EC:2.1.1.-]
101050821  NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 [KO:K18163]
101051914  NDUFAF7; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 isoform X1 [KO:K18164]
101037821  uncharacterized protein C17orf89 homolog [KO:K24726]
101049489  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
101044303  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
101051329  succinate dehydrogenase cytochrome b560 subunit, mitochondrial-like isoform X2 [KO:K00236]
101052834  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236]
101028994  SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X1 [KO:K00237]
101051648  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
13228909  CYTB; cytochrome b [KO:K00412]
101028265  cytochrome c1, heme protein, mitochondrial [KO:K00413]
101044497  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
101027563  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
101048570  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
101033949  cytochrome b-c1 complex subunit 7 [KO:K00417]
101035084  cytochrome b-c1 complex subunit 8 [KO:K00418]
101049239  cytochrome b-c1 complex subunit 9 [KO:K00419]
101046568  cytochrome b-c1 complex subunit 9 [KO:K00419]
101029246  cytochrome b-c1 complex subunit 10 [KO:K00420]
13228913  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
13228914  COX2; cytochrome c oxidase subunit II [KO:K02261]
13228917  COX3; cytochrome c oxidase subunit III [KO:K02262]
101034432  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
101039974  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
101040245  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
101035543  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
101035057  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
104652045  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
101046056  cytochrome c oxidase subunit 6B1-like [KO:K02267]
101053685  cytochrome c oxidase subunit 6B1 [KO:K02267]
101048324  cytochrome c oxidase subunit 6B2 [KO:K02267]
104651513  cytochrome c oxidase subunit 6C [KO:K02268]
104653005  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
101040014  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
101047978  LOW QUALITY PROTEIN: cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
101031292  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
101052499  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
101048999  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
104650017  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
101037219  cytochrome c oxidase subunit 8C, mitochondrial [KO:K02273]
101045622  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
101040253  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
101041549  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
101030790  cytochrome c oxidase assembly protein COX14 [KO:K18181]
101046257  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
101053452  cytochrome c oxidase copper chaperone [KO:K02260]
101048012  mitochondrial inner membrane protein COX18 isoform X1 [KO:K17797]
104650203  cytochrome c oxidase assembly protein COX19 [KO:K18183]
101039309  cytochrome c oxidase protein 20 homolog [KO:K18184]
101051193  cytochrome c oxidase assembly factor 1 homolog [KO:K18173]
101036388  cytochrome c oxidase assembly factor 3 homolog, mitochondrial [KO:K18175]
101037862  cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X2 [KO:K18177]
101039880  cytochrome c oxidase assembly factor 5 [KO:K18178]
104649867  cytochrome c oxidase assembly factor 6 homolog [KO:K18179]
101035940  cytochrome c oxidase assembly factor 7 [KO:K18180]
101039546  ATP5A1; ATP synthase subunit alpha, mitochondrial [KO:K02132]
101030792  ATP5B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
101032905  ATP5C1; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
101033378  ATP5D; ATP synthase subunit delta, mitochondrial [KO:K02134]
101042605  ATP5E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
101032192  ATP5O; ATP synthase subunit O, mitochondrial [KO:K02137]
101044387  ATP synthase subunit O, mitochondrial-like [KO:K02137]
101046136  ATP synthase subunit O, mitochondrial-like [KO:K02137]
13228916  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
101046852  ATP5F1; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
101041657  ATP5G1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
101034795  ATP5G2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
101035317  ATP5G3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
101043332  ATP5H; ATP synthase subunit d, mitochondrial [KO:K02138]
101029644  ATP synthase subunit d, mitochondrial-like isoform X1 [KO:K02138]
101029354  ATP synthase subunit d, mitochondrial-like isoform X1 [KO:K02138]
101039563  LOW QUALITY PROTEIN: ATP synthase subunit d, mitochondrial-like [KO:K02138]
104652365  ATP5J2; ATP synthase subunit f, mitochondrial [KO:K02130]
101031595  ATP synthase subunit f, mitochondrial-like isoform X1 [KO:K02130]
101030869  ATP5J; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
13228915  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
101028470  ATP5L; ATP synthase subunit g, mitochondrial [KO:K02140]
104653108  uncharacterized protein LOC104653108 [KO:K02140]
101033529  CPT2; carnitine O-palmitoyltransferase 2, mitochondrial [KO:K08766] [EC:2.3.1.21]
101028151  SLC25A29; mitochondrial basic amino acids transporter [KO:K15109]
101045290  SLC25A20; mitochondrial carnitine/acylcarnitine carrier protein [KO:K15109]
101044692  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [KO:K08765] [EC:2.3.1.21]
101045068  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1 [KO:K19523] [EC:2.3.1.21]
101043828  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [KO:K19524] [EC:2.3.1.21]
Compound
C00002  ATP
C00004  NADH
C00008  ADP
C00010  CoA
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00080  H+
C00116  Glycerol
C00162  Fatty acid
C00165  Diacylglycerol
C00318  L-Carnitine
C00422  Triacylglycerol
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00745  Nicotine
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01352  FADH2
C01885  1-Acylglycerol
C02301  O-Acylcarnitine
C02465  Triiodothyronine
C11695  Anandamide
C13856  2-Arachidonoylglycerol
Reference
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Nat Rev Mol Cell Biol 17:480-95 (2016)
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Mol Cell Biol 25:5466-79 (2005)
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  Title
JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis.
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Nat Commun 6:7052 (2015)
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Mol Cell 57:235-46 (2015)
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Cell Rep 15:2536-49 (2016)
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Cell Rep 17:29-36 (2016)
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Reference
PMID:22020112
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The mitochondrial carnitine/acylcarnitine carrier: function, structure and physiopathology.
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Mol Aspects Med 32:223-33 (2011)
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Reference
PMID:26303601
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Nat Rev Endocrinol 11:617-25 (2015)
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PMID:28955734
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Chronic high-fat feeding impairs adaptive induction of mitochondrial fatty acid combustion-associated proteins in brown adipose tissue of mice.
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Biochem Biophys Rep 10:32-38 (2017)
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Related
pathway
sbq00020  Citrate cycle (TCA cycle)
sbq00190  Oxidative phosphorylation
sbq04010  MAPK signaling pathway
sbq04022  cGMP-PKG signaling pathway
sbq04024  cAMP signaling pathway
sbq04150  mTOR signaling pathway
sbq04923  Regulation of lipolysis in adipocytes
KO pathway
ko04714   
LinkDB

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