KEGG   PATHWAY: tgu05168
Entry
tgu05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Taeniopygia guttata (zebra finch)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
tgu05168  Herpes simplex virus 1 infection
tgu05168

Organism
Taeniopygia guttata (zebra finch) [GN:tgu]
Gene
100223400  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
100219054  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
100225072  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 [KO:K07209] [EC:2.7.11.10]
116807244  inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [KO:K07209] [EC:2.7.11.10]
100221281  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
115491960  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
100220015  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
100221542  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X2 [KO:K02580]
115492066  RELA; transcription factor p65 isoform X1 [KO:K04735]
100225317  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
100227285  NECTIN1; nectin-1 isoform X2 [KO:K06081]
100218949  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [KO:K07293] [EC:3.1.3.48]
115491489  integrin alpha-5-like [KO:K06484]
100226539  ITGB3; integrin beta-3 [KO:K06493]
100227812  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
100229485  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
100219285  CARD9; caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
100222821  C3; complement C3 isoform X1 [KO:K03990]
100227865  C5; complement C5 isoform X2 [KO:K03994]
100219691  TLR2; toll-like receptor 2 isoform X2 [KO:K10159]
100223638  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
100222919  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
100232771  TLR3; toll-like receptor 3 [KO:K05401]
100231928  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
100227974  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
100229606  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
100221443  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X5 [KO:K04427] [EC:2.7.11.25]
100223478  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
100225126  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
100227014  IL1B; interleukin-1 beta isoform X2 [KO:K04519]
105758643  CCL17; C-C motif chemokine 17 [KO:K12499]
116809122  C-C motif chemokine 5-like [KO:K12499]
100220682  IL6; interleukin-6 isoform X2 [KO:K05405]
100217488  IL12B; interleukin-12 subunit beta isoform X2 [KO:K05425]
115494797  interleukin-12 subunit beta-like [KO:K05425]
100222705  DDX58; probable ATP-dependent RNA helicase DDX58 isoform X1 [KO:K12646] [EC:5.6.2.6]
100225529  IFIH1; interferon-induced helicase C domain-containing protein 1 isoform X1 [KO:K12647] [EC:5.6.2.6]
100218625  MAVS; mitochondrial antiviral-signaling protein [KO:K12648]
100218184  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
100228860  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
100225715  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
100228379  interferon omega-1 [KO:K05414]
115491042  interferon-like [KO:K05414]
105760863  LOW QUALITY PROTEIN: interferon-like [KO:K05414]
116806752  interferon-like [KO:K05414]
100224044  CGAS; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
100218078  STING1; stimulator of interferon genes protein isoform X1 [KO:K12654]
100190013  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
100190751  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
100224238  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100223214  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [KO:K16194] [EC:2.7.11.1]
100223594  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
100223479  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
100232582  EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
100190668  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
100225688  EIF2B1; translation initiation factor eIF-2B subunit alpha isoform X1 [KO:K03239]
100190609  EIF2B2; translation initiation factor eIF-2B subunit beta [KO:K03754]
100226101  EIF2B3; translation initiation factor eIF-2B subunit gamma isoform X1 [KO:K03241]
100230981  EIF2B4; translation initiation factor eIF-2B subunit delta isoform X4 [KO:K03680]
100225935  EIF2B5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
100225405  HCFC2; host cell factor 2 isoform X2 [KO:K27390]
100218624  POU2F3; POU domain, class 2, transcription factor 3 [KO:K09364]
100219507  POU2F1; POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
115490564  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
115497673  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
100227853  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
115496244  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
115491597  non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
100221342  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
105760310  signal transducer and activator of transcription 2 [KO:K11221]
115491620  interferon regulatory factor 9-like [KO:K04693]
100224667  uncharacterized protein LOC100224667 [KO:K09228]
115494107  zinc finger protein 316-like [KO:K09228]
105760267  zinc finger protein 883 isoform X1 [KO:K09228]
105758954  neurofilament heavy polypeptide isoform X1 [KO:K09228]
105758956  zinc finger protein 398 isoform X1 [KO:K09228]
105759121  zinc finger protein 493 [KO:K09228]
115493334  zinc finger protein 239-like [KO:K09228]
115490572  zinc finger protein 239-like [KO:K09228]
100222056  zinc finger protein 239 isoform X1 [KO:K09228]
100220872  zinc finger protein 239-like [KO:K09228]
115493087  zinc finger protein 135 [KO:K09228]
115492069  zinc finger protein 397-like [KO:K09228]
115492522  zinc finger protein 239-like [KO:K09228]
100220738  zinc finger protein 239-like [KO:K09228]
105760508  zinc finger protein 436-like [KO:K09228]
115492498  zinc finger protein 239-like [KO:K09228]
100220454  LOW QUALITY PROTEIN: zinc finger protein 665 [KO:K09228]
100220813  LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 2-like [KO:K09228]
100230077  LOW QUALITY PROTEIN: zinc finger protein 501-like [KO:K09228]
100231014  zinc finger protein 3-like [KO:K09228]
100232749  zinc finger protein 501 [KO:K09228]
101233471  zinc finger protein 391 [KO:K09228]
101233943  LOW QUALITY PROTEIN: zinc finger protein 436 [KO:K09228]
105759787  LOW QUALITY PROTEIN: zinc finger protein 883 [KO:K09228]
105759916  zinc finger protein 239-like [KO:K09228]
115492305  LOW QUALITY PROTEIN: zinc finger protein 135-like [KO:K09228]
115492329  zinc finger protein 271-like [KO:K09228]
115492352  zinc finger protein 239 [KO:K09228]
115492816  zinc finger protein 239-like isoform X1 [KO:K09228]
115493091  zinc finger protein 3 homolog [KO:K09228]
115493097  zinc finger protein 239-like [KO:K09228]
115493101  LOW QUALITY PROTEIN: zinc finger protein 883-like [KO:K09228]
115493103  zinc finger protein 239-like [KO:K09228]
115493304  zinc finger protein 391-like [KO:K09228]
116806636  zinc finger protein 239-like [KO:K09228]
116807032  zinc finger protein 239-like [KO:K09228]
116807035  zinc finger protein 572-like [KO:K09228]
116807038  zinc finger protein 239-like [KO:K09228]
116807102  zinc finger protein 3 homolog [KO:K09228]
116807115  zinc finger protein 239-like [KO:K09228]
116807369  zinc finger protein 184-like [KO:K09228]
116807377  zinc finger protein 239-like [KO:K09228]
116807561  zinc finger protein 239-like [KO:K09228]
116807578  zinc finger protein 239-like [KO:K09228]
116807694  zinc finger protein OZF-like [KO:K09228]
116807695  zinc finger protein 239-like [KO:K09228]
116807943  zinc finger protein 27-like [KO:K09228]
116807118  zinc finger protein 239-like [KO:K09228]
100226664  IFNG; interferon gamma [KO:K04687]
100222262  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
100217912  IFNGR2; interferon gamma receptor 2 isoform X2 [KO:K05133]
100225452  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
115493070  DAXX; death domain-associated protein 6 [KO:K02308]
115492664  antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
101234078  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
100190479  CALR; calreticulin [KO:K08057]
100231469  class I histocompatibility antigen, F10 alpha chain isoform X3 [KO:K06751]
100190403  B2M; beta-2-microglobulin precursor [KO:K08055]
100225145  class II histocompatibility antigen, B-L beta chain-like isoform X1 [KO:K06752]
115492234  HLA class II histocompatibility antigen, DM beta chain-like [KO:K06752]
115493267  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
115493286  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
115493243  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
115493268  class II histocompatibility antigen, B-L beta chain-like isoform X1 [KO:K06752]
115493254  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
115493246  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
116807535  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
116807540  class II histocompatibility antigen, B-L beta chain-like [KO:K06752]
100229033  CD74; HLA class II histocompatibility antigen gamma chain [KO:K06505]
100224188  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100229768  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100219602  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
100221185  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
100223949  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100226234  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
100217811  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100232504  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100228268  TSC1; hamartin isoform X1 [KO:K07206]
100222231  TSC2; tuberin isoform X1 [KO:K07207]
100190126  RHEB; GTP-binding protein Rheb [KO:K07208]
100219695  MTOR; serine/threonine-protein kinase mTOR isoform X2 [KO:K07203] [EC:2.7.11.1]
100230789  EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 isoform X1 [KO:K07205]
100219206  SRPK1; SRSF protein kinase 1 isoform X2 [KO:K15409] [EC:2.7.11.1]
100219525  SRSF1; serine/arginine-rich splicing factor 1 [KO:K12890]
100227528  SRSF2; serine/arginine-rich splicing factor 2 [KO:K12891]
116809219  cactin-like [KO:K12891]
100190651  SRSF3; serine/arginine-rich splicing factor 3 [KO:K12892]
100217999  SRSF4; serine/arginine-rich splicing factor 4 isoform X2 [KO:K12893]
100231521  SRSF5; serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
100220017  serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
100228119  SRSF6; serine/arginine-rich splicing factor 6 [KO:K12893]
100190231  SRSF7; serine/arginine-rich splicing factor 7 [KO:K12896]
100222291  serine/arginine-rich splicing factor 7 isoform X2 [KO:K12896]
115492082  NXF1; nuclear RNA export factor 1 [KO:K14284]
100190053  ALYREF; THO complex subunit 4 [KO:K12881]
100230435  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
100225721  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
100227485  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
100224702  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
100229649  FADD; FAS-associated death domain protein [KO:K02373]
100222284  caspase-8 [KO:K04398] [EC:3.4.22.61]
100223333  caspase-8 [KO:K04398] [EC:3.4.22.61]
100228765  BID; LOW QUALITY PROTEIN: BH3-interacting domain death agonist [KO:K04726]
100221739  BAK1; bcl-2 homologous antagonist/killer isoform X2 [KO:K14021]
100224888  BCL2; apoptosis regulator Bcl-2 isoform X2 [KO:K02161]
100224900  BCL2L1; bcl-2-like protein 1 [KO:K04570]
100223555  CYCS; cytochrome c [KO:K08738]
100222477  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
100227981  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
100230799  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
PMID:15056211
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
  Journal
Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
PMID:12855695
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
PMID:24262390
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
PMID:26952111
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
PMID:21994567
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
PMID:15276609
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
  Journal
Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
PMID:29298887
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
PMID:19344302
  Authors
Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
  Journal
Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
PMID:23115300
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
  Journal
J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
PMID:17229694
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
Reference
PMID:12826401
  Authors
Wysocka J, Herr W
  Title
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
  Journal
Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
Reference
PMID:27367734
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
  Journal
Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
Reference
PMID:15163721
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
Reference
PMID:23864622
  Authors
Gu H, Zheng Y, Roizman B
  Title
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
  Journal
J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
Reference
PMID:21994592
  Authors
Tavalai N, Stamminger T
  Title
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
  Journal
Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
Reference
PMID:21146386
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:12960333
  Authors
Neumann J, Eis-Hubinger AM, Koch N
  Title
Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
  Journal
J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
Reference
PMID:25798530
  Authors
Liu X, Cohen JI
  Title
The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
  Journal
Virology 479-480:568-77 (2015)
DOI:10.1016/j.virol.2015.02.040
Reference
PMID:28468873
  Authors
Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
  Journal
J Virol 91:e00295-17 (2017)
DOI:10.1128/JVI.00295-17
Reference
PMID:18508584
  Authors
Sandri-Goldin RM
  Title
The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
  Journal
Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
Reference
PMID:15078920
  Authors
Sandri-Goldin RM
  Title
Viral regulation of mRNA export.
  Journal
J Virol 78:4389-96 (2004)
DOI:10.1128/JVI.78.9.4389-4396.2004
Reference
PMID:27154074
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
tgu03040  Spliceosome
tgu03050  Proteasome
tgu04115  p53 signaling pathway
tgu04210  Apoptosis
tgu04620  Toll-like receptor signaling pathway
tgu04622  RIG-I-like receptor signaling pathway
KO pathway
ko05168   
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