KEGG   ORTHOLOGY: K00460
Entry
K00460                      KO                                     

Name
ALOX15
Definition
arachidonate 15-lipoxygenase [EC:1.13.11.33]
Pathway
map00590  Arachidonic acid metabolism
map00591  Linoleic acid metabolism
map01100  Metabolic pathways
map04216  Ferroptosis
map04217  Necroptosis
map04726  Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K00460  ALOX15; arachidonate 15-lipoxygenase
   00591 Linoleic acid metabolism
    K00460  ALOX15; arachidonate 15-lipoxygenase
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K00460  ALOX15; arachidonate 15-lipoxygenase
   04217 Necroptosis
    K00460  ALOX15; arachidonate 15-lipoxygenase
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K00460  ALOX15; arachidonate 15-lipoxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.33  arachidonate 15-lipoxygenase
     K00460  ALOX15; arachidonate 15-lipoxygenase
Other DBs
RN: R01593 R03626
GO: 0050473
Genes
HSA: 246(ALOX15)
PTR: 748294(ALOX15) 750581
PPS: 100990568(ALOX15)
GGO: 101130490(ALOX15) 101138809
PON: 100174413(ALOX15)
NLE: 100598410(ALOX15) 100599862
MCC: 100425071 709212(ALOX15) 713683
MCF: 102124513(ALOX15) 102137290
CSAB: 103242192(ALOX15) 103242262
CATY: 105583615(ALOX15) 105584566
PANU: 101014249(ALOX15) 101016522
RRO: 104673354 104677212(ALOX15)
RBB: 108514294 108520722(ALOX15)
TFN: 117067819 117067883(ALOX15)
CJC: 100388086(ALOX15)
SBQ: 101031385(ALOX15)
MMUR: 105879207(ALOX15) 105879210
MMU: 11687(Alox15)
MCAL: 110305643
MPAH: 110332116
RNO: 81639(Alox15)
MUN: 110541720 110541721 110542750
CGE: 100764916(Alox15)
PLEU: 114693221 114693249
NGI: 103752179(Alox15)
CCAN: 109697448(Alox15)
OCU: 100009114(ALOX15) 100271999(ALOX12)
TUP: 102478167(ALOX15) 102488255 102495183
CFA: 119871841 489458(ALOX15)
VVP: 112924802(ALOX15) 112924804
VLG: 121500376
AML: 100479002(ALOX15)
UMR: 103660453(ALOX15)
UAH: 113271093(ALOX15)
ORO: 101379891 101380189(ALOX15)
ELK: 111161195
MPUF: 101685628 101685913
EJU: 114225435 114225462
MLX: 117999977
HHV: 120227740
BTA: 282139(ALOX15)
BOM: 102285373 102285661(ALOX15)
BIU: 109574003
BBUB: 102396987 102397311
CHX: 102178853 102179132(ALOX15)
OAS: 101116587(ALOX15)
ODA: 120866092 120866093
SSC: 396971(ALOX15)
CFR: 102522465 116669221
CDK: 105106001
BACU: 103006231(ALOX15)
LVE: 103073785(ALOX15)
OOR: 101281563(ALOX15)
DLE: 111185975(ALOX15)
PCAD: 102986457(ALOX15)
ECB: 100072900(ALOX15)
EPZ: 103561432(ALOX15)
EAI: 106844159(ALOX15)
MYB: 102240358
MYD: 102765226 102769401
MMYO: 118672418(ALOX15)
MNA: 107528023(ALOX15)
HAI: 109394595(ALOX15)
DRO: 112308861(ALOX15)
SHON: 119001049(ALOX15)
AJM: 119043192(ALOX15)
MMF: 118634572(ALOX15)
PALE: 102896986(ALOX15)
RAY: 107509499(ALOX15)
MJV: 108386766(ALOX15)
TOD: 119232067
LAV: 100660599 104845446
TMU: 101359454
MDO: 100015976(ALOX15)
PCW: 110194258
 » show all
Reference
  Authors
Kuhn H, Walther M, Kuban RJ
  Title
Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications.
  Journal
Prostaglandins Other Lipid Mediat 68-69:263-90 (2002)
DOI:10.1016/S0090-6980(02)00035-7
Reference
PMID:3202857
  Authors
Sigal E, Craik CS, Highland E, Grunberger D, Costello LL, Dixon RA, Nadel JA
  Title
Molecular cloning and primary structure of human 15-lipoxygenase.
  Journal
Biochem Biophys Res Commun 157:457-64 (1988)
DOI:10.1016/S0006-291X(88)80271-7
  Sequence
[hsa:246]
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