KEGG   ORTHOLOGY: K05071
Entry
K05071                      KO                                     

Name
IL4R, CD124
Definition
interleukin 4 receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
Disease
H00079  Asthma
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
   04151 PI3K-Akt signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05071  IL4R, CD124; interleukin 4 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05071  IL4R, CD124; interleukin 4 receptor
   04658 Th1 and Th2 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
   04659 Th17 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05071  IL4R, CD124; interleukin 4 receptor
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05071  IL4R, CD124; interleukin 4 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05071  IL4R, CD124; interleukin 4 receptor
   04090 CD molecules
    K05071  IL4R, CD124; interleukin 4 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05071  IL4R, CD124; interleukin 4 receptor
CD molecules [BR:ko04090]
 Proteins
  K05071  CD124, IL4R; interleukin 4 receptor
Other DBs
GO: 0004913
Genes
HSA: 3566(IL4R)
PTR: 454005(IL4R)
PPS: 100969808(IL4R)
GGO: 101124934(IL4R)
PON: 100449812(IL4R)
NLE: 100606206(IL4R)
MCC: 705404(IL4R)
MCF: 102133649(IL4R)
CSAB: 103230069(IL4R)
RRO: 104665638(IL4R)
RBB: 108538856(IL4R)
CJC: 100412639(IL4R)
SBQ: 101044733(IL4R)
MMU: 16190(Il4ra)
MCAL: 110299093(Il4r)
MPAH: 110322992(Il4r)
RNO: 25084(Il4r)
MUN: 110564641(Il4r)
CGE: 100762840(Il4r)
NGI: 103741011(Il4r)
HGL: 101704138(Il4r)
CCAN: 109698033(Il4r)
OCU: 100337721(IL4R)
TUP: 102469844(IL4R)
CFA: 489957(IL4R)
VVP: 112929179(IL4R)
AML: 100476095(IL4R)
UMR: 103657902(IL4R)
UAH: 113267608(IL4R)
ORO: 101373228(IL4R)
ELK: 111162191
FCA: 101096277(IL4R)
PTG: 102949893(IL4R)
PPAD: 109256524(IL4R)
AJU: 106966182(IL4R)
BTA: 404154(IL4R)
BOM: 102273764(IL4R)
BIU: 109578521(IL4R)
BBUB: 102394204(IL4R)
CHX: 102176382(IL4R)
OAS: 101109063(IL4R)
SSC: 397614(IL4R)
CFR: 102504937(IL4R)
CDK: 105098257(IL4R)
BACU: 103017383(IL4R)
LVE: 103085500(IL4R)
OOR: 101281237(IL4R)
DLE: 111182213(IL4R)
PCAD: 102979109(IL4R)
ECB: 791252(IL4R)
EPZ: 103556347(IL4R)
EAI: 106829083(IL4R)
MYB: 102243995
MYD: 102752440(IL4R)
HAI: 109385965(IL4R)
DRO: 112304724 112304842(IL4R)
PALE: 102882815(IL4R)
RAY: 107506151(IL4R)
MJV: 108405149(IL4R)
LAV: 100654822(IL4R)
TMU: 101351007
MDO: 103092514(IL4R)
SHR: 100922104(IL4R)
PCW: 110221658(IL4R)
OAA: 103164911(IL4R)
GGA: 416585(IL4R)
MGP: 100541265(IL4R)
CJO: 107320714(IL4R)
NMEL: 110405596(IL4R)
APLA: 101796552(IL4R)
ACYG: 106046042(IL4R)
TGU: 100220266(IL4R)
LSR: 110477758(IL4R)
SCAN: 103817792(IL4R)
GFR: 102032458(IL4R)
FAB: 101812385(IL4R)
PHI: 102114232(IL4R)
PMAJ: 107211179(IL4R)
CCAE: 111936216(IL4R)
CCW: 104684903(IL4R)
ETL: 114061435(IL4R)
FPG: 101913747(IL4R)
FCH: 102059925(IL4R)
CLV: 102092650(IL4R)
EGZ: 104131347(IL4R)
NNI: 104015288(IL4R)
ACUN: 113485935(IL4R)
PADL: 103913920(IL4R)
AAM: 106486134(IL4R)
ASN: 102384900
AMJ: 102563749(IL4R)
PSS: 102459395(IL4R)
CMY: 102929479(IL4R)
CPIC: 101942260(IL4R)
ACS: 103281083(il4r)
PVT: 110085007
PBI: 103065038(IL4R)
TSR: 106546610(IL4R)
PMUA: 114584165(IL4R)
XTR: 101732450(il4r) 105948365
DRE: 563674(il4r.2)
SRX: 107745579
IPU: 108257347(il4r) 108280483
PHYP: 113535949(il4r) 113546473
AMEX: 111195543
EEE: 113575903(il4r)
ONL: 100705710
XMA: 111608325
CVG: 107086945
AOCE: 111587969
CSEM: 103398546
POV: 109624836
LCF: 108877014
SDU: 111219228
BPEC: 110175441
SASA: 100195064(il4ra) 106601108
SALP: 111979922
SFM: 108932964
PKI: 111846440(il4r)
LCM: 102349939
CMK: 103186635(il4r)
 » show all
Reference
PMID:2307934
  Authors
Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.
  Title
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
  Journal
J Exp Med 171:861-73 (1990)
DOI:10.1084/jem.171.3.861
  Sequence
[hsa:3566]
Reference
PMID:8124718
  Authors
Keegan AD, Nelms K, White M, Wang LM, Pierce JH, Paul WE
  Title
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.
  Journal
Cell 76:811-20 (1994)
DOI:10.1016/0092-8674(94)90356-5
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