KEGG ORTHOLOGY: K05071

ORTHOLOGY: K05071

Entry

K05071 KO

Name

IL4R, CD124

Definition

interleukin 4 receptor

Pathway

ko04060

Cytokine-cytokine receptor interaction

ko04151

PI3K-Akt signaling pathway

ko04630

JAK-STAT signaling pathway

ko04640

Hematopoietic cell lineage

ko04658

Th1 and Th2 cell differentiation

ko04659

Th17 cell differentiation

ko05200

Pathways in cancer

ko05321

Inflammatory bowel disease

Disease

H00079

Asthma

H01358

Atopic dermatitis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
   04151 PI3K-Akt signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05071  IL4R, CD124; interleukin 4 receptor
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05071  IL4R, CD124; interleukin 4 receptor
   04658 Th1 and Th2 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
   04659 Th17 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05071  IL4R, CD124; interleukin 4 receptor
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05071  IL4R, CD124; interleukin 4 receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05071  IL4R, CD124; interleukin 4 receptor
   04090 CD molecules
    K05071  IL4R, CD124; interleukin 4 receptor
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IL2 receptor family
   K05071  IL4R, CD124; interleukin 4 receptor
CD molecules [BR:ko04090]
Proteins
  K05071  CD124, IL4R; interleukin 4 receptor

Other DBs

GO:

0004913

Genes

HSA:	3566(IL4R)

PTR:	454005(IL4R)

PPS:	100969808(IL4R)

GGO:	101124934(IL4R)

PON:	100449812(IL4R)

NLE:	100606206(IL4R)

MCC:	705404(IL4R)

MCF:	102133649(IL4R)

CSAB:

103230069(IL4R)

RRO:	104665638(IL4R)

RBB:	108538856(IL4R)

CJC:	100412639(IL4R)

SBQ:	101044733(IL4R)

MMU:	16190(Il4ra)

MCAL:

110299093(Il4r)

MPAH:

110322992(Il4r)

RNO:	25084(Il4r)

MUN:	110564641(Il4r)

CGE:	100762840(Il4r)

NGI:	103741011(Il4r)

HGL:	101704138(Il4r)

CCAN:

109698033(Il4r)

OCU:	100337721(IL4R)

TUP:	102469844(IL4R)

CFA:	489957(IL4R)

VVP:	112929179(IL4R)

AML:	100476095(IL4R)

UMR:	103657902(IL4R)

UAH:	113267608(IL4R)

ORO:	101373228(IL4R)

ELK:

111162191

FCA:	101096277(IL4R)

PTG:	102949893(IL4R)

PPAD:

109256524(IL4R)

AJU:	106966182(IL4R)

BTA:	404154(IL4R)

BOM:	102273764(IL4R)

BIU:	109578521(IL4R)

BBUB:

102394204(IL4R)

CHX:	102176382(IL4R)

OAS:	101109063(IL4R)

SSC:	397614(IL4R)

CFR:	102504937(IL4R)

CDK:	105098257(IL4R)

BACU:

103017383(IL4R)

LVE:	103085500(IL4R)

OOR:	101281237(IL4R)

DLE:	111182213(IL4R)

PCAD:

102979109(IL4R)

ECB:	791252(IL4R)

EPZ:	103556347(IL4R)

EAI:	106829083(IL4R)

MYB:

102243995

MYD:	102752440(IL4R)

MNA:	107539670 107544754

HAI:	109385965(IL4R)

DRO:	112304724 112304842(IL4R)

PALE:

102882815(IL4R)

RAY:	107506151(IL4R)

MJV:	108405149(IL4R)

LAV:	100654822(IL4R)

TMU:

101351007

MDO:	103092514(IL4R)

SHR:	100922104(IL4R)

PCW:	110221658(IL4R)

OAA:	103164911(IL4R)

GGA:	416585(IL4R)

MGP:	100541265(IL4R)

CJO:	107320714(IL4R)

NMEL:

110405596(IL4R)

APLA:

101796552(IL4R)

ACYG:

106046042(IL4R)

TGU:	100220266(IL4R)

LSR:	110477758(IL4R)

SCAN:

103817792(IL4R)

GFR:	102032458(IL4R)

FAB:	101812385(IL4R)

PHI:	102114232(IL4R)

PMAJ:

107211179(IL4R)

CCAE:

111936216(IL4R)

CCW:	104684903(IL4R)

ETL:	114061435(IL4R)

FPG:	101913747(IL4R)

FCH:	102059925(IL4R)

CLV:	102092650(IL4R)

EGZ:	104131347(IL4R)

NNI:	104015288(IL4R)

ACUN:

113485935(IL4R)

PADL:

103913920(IL4R)

AAM:	106486134(IL4R)

ASN:

102384900

AMJ:	102563749(IL4R)

PSS:	102459395(IL4R)

CMY:	102929479(IL4R)

CPIC:

101942260(IL4R)

ACS:	103281083(il4r)

PVT:

110085007

PBI:	103065038(IL4R)

TSR:	106546610(IL4R)

PMUA:

114584165(IL4R)

XLA:	108701563 108703132

XTR:	101732450(il4r) 105948365

DRE:	563674(il4r.2)

SRX:

107745579

SANH:

107674679 107703316

SGH:	107564686 107564689 107568934

CCAR:

109051510 109051533 109054693 109056524 109080519

IPU:	108257347(il4r) 108280483

PHYP:

113535949(il4r) 113546473

AMEX:

111195543

EEE:	113575903(il4r)

ONL:

100705710

OLA:	101171817 111947159

XMA:

CVG:

AOCE:

CSEM:

POV:

LCF:

SDU:

BPEC:

SASA:

100195064(il4ra) 106601108

OTW:	112226040 112226042 112246014

SALP:

111979922

ELS:	105013235 114840419

SFM:

108932964

PKI:	111846440(il4r)

LCM:

102349939

CMK:	103186635(il4r)

» show all

Reference

PMID:2307934

Authors

Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.

Title

Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.

Journal

J Exp Med 171:861-73 (1990)
DOI:10.1084/jem.171.3.861

Sequence

[hsa:3566]

Reference

PMID:8124718

Authors

Keegan AD, Nelms K, White M, Wang LM, Pierce JH, Paul WE

Title

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.

Journal

Cell 76:811-20 (1994)
DOI:10.1016/0092-8674(94)90356-5

LinkDB

DBGET integrated database retrieval system