MODULE: M00527
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Entry
M00527 Pathway Module
Name
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Definition
(K00928,K12524,K12525,K12526) K00133 K01714 K00215 K10206 K01778 (K01586,K12526)
Diagram
Orthology
K00928
,
K12524
,
K12525
,
K12526
aspartate kinase [EC:
2.7.2.4
] [RN:
R00480
]
K00133
aspartate-semialdehyde dehydrogenase [EC:
1.2.1.11
] [RN:
R02291
]
K01714
4-hydroxy-tetrahydrodipicolinate synthase [EC:
4.3.3.7
] [RN:
R10147
]
K00215
4-hydroxy-tetrahydrodipicolinate reductase [EC:
1.17.1.8
] [RN:
R04198
R04199
]
K10206
LL-diaminopimelate aminotransferase [EC:
2.6.1.83
] [RN:
R07613
]
K01778
diaminopimelate epimerase [EC:
5.1.1.7
] [RN:
R02735
]
K01586
,
K12526
diaminopimelate decarboxylase [EC:
4.1.1.20
] [RN:
R00451
]
Ortholog table
Taxonomy
Module table
Class
Pathway modules; Amino acid metabolism; Lysine metabolism
BRITE hierarchy
Pathway
map00300
Lysine biosynthesis
map01230
Biosynthesis of amino acids
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Reaction
R00480
C00049
->
C03082
R02291
C03082
->
C00441
R10147
C00441
->
C20258
R04198
,
R04199
C20258
->
C03972
R07613
C03972
->
C00666
R02735
C00666
->
C00680
R00451
C00680
->
C00047
Compound
C00049
L-Aspartate
C03082
4-Phospho-L-aspartate
C00441
L-Aspartate 4-semialdehyde
C20258
(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate
C03972
2,3,4,5-Tetrahydrodipicolinate
C00666
LL-2,6-Diaminoheptanedioate
C00680
meso-2,6-Diaminoheptanedioate
C00047
L-Lysine
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integrated database retrieval system