Entry
Symbol
PPP3R1, CALNB1, CNB, CNB1
Name
(RefSeq) protein phosphatase 3 regulatory subunit B, alpha
KO
K06268 serine/threonine-protein phosphatase 2B regulatory subunit
Organism
Pathway
hsa04625 C-type lectin receptor signaling pathway
hsa04650 Natural killer cell mediated cytotoxicity
hsa04658 Th1 and Th2 cell differentiation
hsa04660 T cell receptor signaling pathway
hsa04662 B cell receptor signaling pathway
hsa05022 Pathways of neurodegeneration - multiple diseases
hsa05163 Human cytomegalovirus infection
hsa05166 Human T-cell leukemia virus 1 infection
hsa05167 Kaposi sarcoma-associated herpesvirus infection
hsa05170 Human immunodeficiency virus 1 infection
hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
Network
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
nt06161 Human immunodeficiency virus 1 (HIV-1)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165 Epstein-Barr virus (EBV)
nt06167 Human cytomegalovirus (HCMV)
nt06220 Calcium signaling (cancer)
nt06528 Calcium signaling
nt06537 TCR/BCR signaling
Element
N00147 EGF-EGFR-PLCG-calcineurin signaling pathway
N00401 CXCR4-GNAQ-PLCB/G-calcineurin signaling pathway
N00487 BCR-PLCG-Calcineurin signaling pathway
N01647 Ca2+/CAM-CN signaling pathway
Drug target
Brite
KEGG Orthology (KO) [BR:hsa00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
5534 (PPP3R1)
04022 cGMP-PKG signaling pathway
5534 (PPP3R1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
5534 (PPP3R1)
04660 T cell receptor signaling pathway
5534 (PPP3R1)
04658 Th1 and Th2 cell differentiation
5534 (PPP3R1)
04659 Th17 cell differentiation
5534 (PPP3R1)
04662 B cell receptor signaling pathway
5534 (PPP3R1)
09152 Endocrine system
04922 Glucagon signaling pathway
5534 (PPP3R1)
04921 Oxytocin signaling pathway
5534 (PPP3R1)
04924 Renin secretion
5534 (PPP3R1)
09156 Nervous system
04724 Glutamatergic synapse
5534 (PPP3R1)
04720 Long-term potentiation
5534 (PPP3R1)
09158 Development and regeneration
04360 Axon guidance
5534 (PPP3R1)
04380 Osteoclast differentiation
5534 (PPP3R1)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
5534 (PPP3R1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
5534 (PPP3R1)
05170 Human immunodeficiency virus 1 infection
5534 (PPP3R1)
05163 Human cytomegalovirus infection
5534 (PPP3R1)
05167 Kaposi sarcoma-associated herpesvirus infection
5534 (PPP3R1)
09171 Infectious disease: bacterial
05152 Tuberculosis
5534 (PPP3R1)
09164 Neurodegenerative disease
05010 Alzheimer disease
5534 (PPP3R1)
05014 Amyotrophic lateral sclerosis
5534 (PPP3R1)
05020 Prion disease
5534 (PPP3R1)
05022 Pathways of neurodegeneration - multiple diseases
5534 (PPP3R1)
09165 Substance dependence
05031 Amphetamine addiction
5534 (PPP3R1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
5534 (PPP3R1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:hsa01009 ]
5534 (PPP3R1)
Protein phosphatases and associated proteins [BR:hsa01009 ]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Regulatory subunits
5534 (PPP3R1)
BRITE hierarchy
SSDB
Ortholog Paralog Gene cluster GFIT
Motif
Motif
Other DBs
Structure
PDB PDBj
LinkDB
All DBs
Position
2:complement(68178857..68252532)
Genome browser
AA seq
170 aa AA seq DB search
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
NT seq
513 nt NT seq +upstream nt +downstream nt
atgggaaatgaggcaagttatcctttggaaatgtgctcacactttgatgcggatgaaatt
aaaaggctaggaaagagatttaagaagcttgatttggacaattctggttctttgagtgtg
gaagagttcatgtctctgcctgagttacaacagaatcctttagtacagcgagtaatagat
atattcgacacagatgggaatggagaagtagactttaaagaattcattgagggcgtctct
cagttcagtgtcaaaggagataaggagcagaaattgaggtttgctttccgtatctatgac
atggataaagatggctatatttccaatggggaactcttccaggtattgaagatgatggtg
gggaacaatctgaaagatacacagttacagcaaattgtagacaaaaccataataaatgca
gataaggatggagatggaagaatatcctttgaagaattctgtgctgttgtaggtggccta
gatatccacaaaaagatggtggtagatgtgtga