Homo sapiens (human): 8440 Entry 8440              CDS       T01001                                  Gene name NCK2, GRB4, NCKbeta Definition (RefSeq) NCK adaptor protein 2   KO K19862   NCK adaptor protein 2 Organism hsa  Homo sapiens (human) Pathway hsa04012   ErbB signaling pathway hsa04360   Axon guidance hsa04660   T cell receptor signaling pathway hsa05130   Pathogenic Escherichia coli infection Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     8440 (NCK2)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     8440 (NCK2)   09158 Development and regeneration    04360 Axon guidance     8440 (NCK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     8440 (NCK2) SSDB Motif Pfam:  SH3_1 SH3_9 SH3_2 SH2 SH3_3 SH3_10 hSH3 SH2_2 Other DBs NCBI-GeneID:  8440 NCBI-ProteinID:  NP_001004720 OMIM:  604930 HGNC:  7665 Ensembl:  ENSG00000071051 Vega:  OTTHUMG00000153116 Pharos:  O43639(Tbio) UniProt:  O43639 A0A0S2Z4M6 LinkDB Structure PDB:  2CIA 4E6R 2JXB 2FRW 2FRY 2B86 1Z3K 1WX6 1U5S Position 2q12.2 AA seq 380 aa MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKN SLKKGSLVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKF AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFL SLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNA RGQVGLVPKNYVVVLSDGPALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALN ERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYK KAPIFTSEHGEKLYLVRALQ NT seq 1143 nt   +upstreamnt  +downstreamnt atgacagaagaagttattgtgatagccaagtgggactacaccgcccagcaggaccaggag ctggacatcaagaagaacgagcggctgtggttgctggacgactccaagacgtggtggcgg gtgaggaacgcggccaacaggacgggctatgtaccgtccaactacgtggagcggaagaac agcctgaagaagggctccctcgtgaagaacctgaaggacacactaggcctcggcaagacg cgcaggaagaccagcgcgcgggatgcgtcccccacgcccagcacggacgccgagtacccc gccaatggcagcggcgccgaccgcatctacgacctcaacatcccggccttcgtcaagttc gcctatgtggccgagcgggaggatgagttgtccctggtgaaggggtcgcgcgtcaccgtc atggagaagtgcagcgacggttggtggcggggcagctacaacgggcagatcggctggttc ccctccaactacgtcttggaggaggtggacgaggcggctgcggagtccccaagcttcctg agcctgcgcaagggcgcctcgctgagcaatggccagggctcccgcgtgctgcatgtggtc cagacgctgtaccccttcagctcagtcaccgaggaggagctcaacttcgagaagggggag accatggaggtgattgagaagccggagaacgaccccgagtggtggaaatgcaaaaatgcc cggggccaggtgggcctcgtccccaaaaactacgtggtggtcctcagtgacgggcctgcc ctgcaccctgcgcacgccccacagataagctacaccgggccctcgtccagcgggcgcttc gcgggcagagagtggtactacgggaacgtgacgcggcaccaggccgagtgcgccctcaac gagcggggcgtggagggcgacttcctcattagggacagcgagtcctcgcccagcgacttc tccgtgtcccttaaagcgtcagggaagaacaaacacttcaaggtgcagctcgtggacaat gtctactgcattgggcagcggcgcttccacaccatggacgagctggtggaacactacaaa aaggcgcccatcttcaccagcgagcacggggagaagctctacctcgtcagggccctgcag tga

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