| Entry |
|
| Name |
Escherichia Eae/Tir to Actin signaling pathway
|
| Definition |
Eae -> Tir -> NCK -> (WASL+WIPF) -> ARP2/3 -> (ACTB,ACTG1) |
| Expanded |
K12790 -> K12784 -> (4690,8440) -> (8976+(7456,147179,644150)) -> (10097+10096+10552+10095+10109+10094+10093+10092+81873) -> (60,71) |
| Class |
nt06180 Pathogenic Escherichia coli
|
| Type |
Pathogen
|
| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
|
| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
|
| Gene |
| 4690 | NCK1; NCK adaptor protein 1 |
| 8440 | NCK2; NCK adaptor protein 2 |
| 8976 | WASL; WASP like actin nucleation promoting factor |
| 7456 | WIPF1; WAS/WASL interacting protein family member 1 |
| 147179 | WIPF2; WAS/WASL interacting protein family member 2 |
| 644150 | WIPF3; WAS/WASL interacting protein family member 3 |
| 10097 | ACTR2; actin related protein 2 |
| 10096 | ACTR3; actin related protein 3 |
| 10552 | ARPC1A; actin related protein 2/3 complex subunit 1A |
| 10095 | ARPC1B; actin related protein 2/3 complex subunit 1B |
| 10109 | ARPC2; actin related protein 2/3 complex subunit 2 |
| 10094 | ARPC3; actin related protein 2/3 complex subunit 3 |
| 10093 | ARPC4; actin related protein 2/3 complex subunit 4 |
| 10092 | ARPC5; actin related protein 2/3 complex subunit 5 |
| 81873 | ARPC5L; actin related protein 2/3 complex subunit 5 like |
|
| Perturbant |
| K12784 (Tir) | tir; translocated intimin receptor |
|
| Reference |
|
| Authors |
Lai Y, Rosenshine I, Leong JM, Frankel G |
| Title |
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli. |
| Journal |
|
| LinkDB |
|