KEGG ORTHOLOGY: K10177

ORTHOLOGY: K10177

Entry

K10177                      KO

Symbol

TBX3

Name

T-box protein 3

Pathway

map04550

Signaling pathways regulating pluripotency of stem cells

Disease

H00637

Ulnar-mammary syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K10177  TBX3; T-box protein 3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K10177  TBX3; T-box protein 3
Transcription factors [BR:ko03000]
Eukaryotic type
  Other transcription factors
   T-box
    K10177  TBX3; T-box protein 3

Genes

HSA:	6926(TBX3)

PTR:	740308(TBX3)

PPS:	100985552(TBX3)

GGO:	101138901(TBX3)

PON:	100451759(TBX3)

PPYG:

129010448(TBX3)

NLE:	100593496(TBX3)

HMH:	116477871(TBX3)

SSYN:

129460302(TBX3)

MCC:	713740(TBX3)

MCF:	102143388(TBX3)

MTHB:

126931446

MNI:	105495376(TBX3)

CSAB:

103239188(TBX3)

CATY:

105592728(TBX3)

PANU:

101020127(TBX3)

TGE:	112635150(TBX3)

MLEU:

105530001(TBX3)

RRO:	104675546(TBX3)

RBB:	108512206(TBX3)

TFN:	117089349(TBX3)

PTEH:

111537373(TBX3)

CANG:

105502287(TBX3)

CJC:	100397791(TBX3)

SBQ:	101037725(TBX3)

CIMI:

108305019(TBX3)

ANAN:

105728576(TBX3)

CSYR:

103274362

MMUR:

105866971(TBX3)

LCAT:

123626008(TBX3)

PCOQ:

105825586(TBX3)

OGA:	100949452(TBX3)

MMU:	21386(Tbx3)

MCAL:

110294499(Tbx3)

MPAH:

110312942(Tbx3)

RNO:	353305(Tbx3)

MCOC:

116068306(Tbx3)

ANU:	117697689(Tbx3)

ASYL:

127673025(Tbx3)

MUN:	110551785(Tbx3)

CGE:	100751320(Tbx3)

MAUA:

101830985(Tbx3)

PROB:

127216021(Tbx3)

PLEU:

114699642(Tbx3)

MORG:

121446288(Tbx3)

MFOT:

126511652

AAMP:

119824926(Tbx3)

NGI:	103745533(Tbx3)

HGL:	101718984(Tbx3)

CPOC:

100724889(Tbx3)

CCAN:

109700126(Tbx3)

DORD:

105984194(Tbx3)

DSP:	122101281(Tbx3)

PLOP:

125349085(Tbx3)

NCAR:

124990971

MMMA:

107156461(Tbx3)

ITI:	101971131(Tbx3)

OCU:

100342578

OPI:	101527592(TBX3)

TUP:	102485888(TBX3)

GVR:	103583293 103609963

CFA:	477494(TBX3)

CLUD:

112676606(TBX3)

VVP:	112932890(TBX3)

VLG:	121475605(TBX3)

NPO:	129508197(TBX3)

AML:	100478252(TBX3)

UMR:	103661299(TBX3)

UAH:	113267002(TBX3)

UAR:	123778647(TBX3)

ELK:

111156410

LLV:

125081847

MPUF:

101694115(TBX3)

MNP:	132023195(TBX3)

MLK:	131811808(TBX3)

NVS:	122903393(TBX3)

ORO:	101380475(TBX3)

EJU:	114219163(TBX3)

ZCA:	113912676(TBX3)

MLX:	118018505(TBX3)

NSU:	110588233(TBX3)

LWW:	102747974(TBX3)

FCA:	101090649(TBX3)

PYU:	121010294(TBX3)

PBG:	122470262(TBX3)

PVIV:

125148824(TBX3)

LRUF:

124518546

PTG:	102955685(TBX3)

PPAD:

109277603(TBX3)

PUC:

125914145

AJU:

106971648

HHV:	120245691(TBX3)

BTA:	781063(TBX3)

BOM:	102274762(TBX3)

BIU:	109570923(TBX3)

BBUB:

102391400(TBX3)

BBIS:

104980189(TBX3)

CHX:	102185207(TBX3)

OAS:	101110875(TBX3)

BTAX:

128062251(TBX3)

CSUM:

138093670(TBX3)

ODA:	120871591(TBX3)

CCAD:

122423119(TBX3)

MREE:

136145602(TBX3)

MBEZ:

129542387(TBX3)

SSC:	100152741(TBX3)

CFR:	102520153(TBX3)

CBAI:

105075694

CDK:	105104923(TBX3)

VPC:	102526953(TBX3)

BACU:

103013355

BMUS:

118880031(TBX3)

LVE:

103084351

OOR:	101271214(TBX3)

DLE:	111162765(TBX3)

PCAD:

102996809(TBX3)

PSIU:

116739074(TBX3)

NASI:

112397367(TBX3)

ECB:	100056019(TBX3)

EPZ:	103548551(TBX3)

EAI:	106842207(TBX3)

MYB:	102245203(TBX3)

MYD:	102766864(TBX3)

MMYO:

118678315(TBX3)

MLF:	102437619(TBX3)

MDT:	132221994(TBX3)

PKL:	118725435(TBX3)

EFUS:

103287249(TBX3)

MNA:	107542389(TBX3)

DRO:	112310474(TBX3)

SHON:

118991138(TBX3)

AJM:	119057420(TBX3)

PDIC:

114509530(TBX3)

PHAS:

123822445(TBX3)

MMF:	118640044(TBX3)

PPAM:

129087480(TBX3)

HAI:	109382276(TBX3)

RFQ:	117017563(TBX3)

PALE:

102882132(TBX3)

PGIG:

120606748(TBX3)

PVP:

105289398

RAY:	107517128(TBX3)

MJV:	108405393(TBX3)

TOD:	119244950(TBX3)

SARA:

101557887(TBX3)

SFUM:

130018291(TBX3)

SETR:

126030569(TBX3)

LAV:	100675695(TBX3)

TMU:

101344225

ETF:	101653172(TBX3)

DNM:	101410743(TBX3)

MDO:	100027044(TBX3)

GAS:	123245028(TBX3)

SHR:	100922535(TBX3)

AFZ:

127545511

PCW:	110222790(TBX3)

TVP:	118829662(TBX3)

PBRV:

138156518(TBX3)

OAA:	100078876(TBX3)

GGA:	374202(TBX3)

PCOC:

116228331(TBX3)

MGP:	100547611 104913609

CJO:	107321441(TBX3)

TPAI:

128083900(TBX3)

LMUT:

125701881(TBX3)

NMEL:

110406274(TBX3)

APLA:

101792038(TBX3)

ACYG:

106031461(TBX3)

CATA:

118253001(TBX3)

AFUL:

116496132(TBX3)

TGU:	100232374(TBX3)

LSR:	110481331(TBX3)

SCAN:

103818056(TBX3)

PMOA:

120510281(TBX3)

OTC:	121344440(TBX3)

PRUF:

121364908(TBX3)

GFR:	102042462(TBX3)

FAB:	101811015(TBX3)

OMA:	130259664(TBX3)

PHI:	102105926(TBX3)

PMAJ:

107211836(TBX3)

CCAE:

111936746(TBX3)

CCW:	104695014(TBX3)

CBRC:

103623791(TBX3)

ACOE:

138119072(TBX3)

ETL:	114069523(TBX3)

ZAB:	102072434(TBX3)

ZLE:	135454721(TBX3)

SVG:	106864877(TBX3)

MMEA:

130578245(TBX3)

HRT:	120760707(TBX3)

SATI:

136368875(TBX3)

FPG:	101910284(TBX3)

FCH:	102055679(TBX3)

SHAB:

115614583(TBX3)

TALA:

104359752(TBX3)

ACHC:

115346055(TBX3)

HLE:	104835945(TBX3)

AGEN:

126041034

HHAR:

128146117(TBX3)

GCL:

127022807

LDI:	104353095(TBX3)

DPUB:

104308452(TBX3)

PPUS:

135188865(TBX3)

EGZ:	104129915(TBX3)

NNI:	104011524(TBX3)

PADL:

103913677(TBX3)

CLV:	102087988(TBX3)

CUCA:

104059361(TBX3)

CPEA:

104386996(TBX3)

CVF:	104288004(TBX3)

RTD:	128917120(TBX3)

AAM:	106482182(TBX3)

AROW:

112970663(TBX3)

NPD:	112945985(TBX3)

TGT:	104571016(TBX3)

DNE:	112994668(TBX3)

SCAM:

104144126(TBX3)

ASN:	102374200(TBX3)

AMJ:	102575375(TBX3)

CPOO:

109313025(TBX3)

GGN:	109290211(TBX3)

PSS:	102445486 102456286

CMY:	102940709(TBX3)

CCAY:

125622977(TBX3)

DCC:	119843922(TBX3)

CPIC:

101935294(TBX3)

TST:	117888096(TBX3)

CABI:

116836430(TBX3)

MRV:	120386062(TBX3)

ACS:

100563414

ASAO:

132781309(TBX3)

PVT:	110086439(TBX3)

SUND:

121916579(TBX3)

PBI:	103065606(TBX3)

PMUR:

107297707(TBX3)

CTIG:

120303186(TBX3)

TSR:	106543717(TBX3)

PGUT:

117657924(TBX3)

APRI:

131185733(TBX3)

NSS:	113427098(TBX3)

VKO:	123032820(TBX3)

PMUA:

114586067(TBX3)

PRAF:

128403438(TBX3)

ZVI:	118075703(TBX3)

HCG:	128337993(TBX3)

GJA:	107105886(TBX3)

STOW:

125442742(TBX3)

EMC:	129341047(TBX3)

XLA:	373612(tbx3.L) 397816(tbx3.S)

XTR:	613116(tbx3)

NPR:	108793894(TBX3)

RTEM:

120938813(TBX3)

BBUF:

120988884(TBX3)

BGAR:

122933706(TBX3)

MUO:	115479439(TBX3)

GSH:	117365394(TBX3)

DRE:	556870(tbx3a)

SRX:	107709835 107728866 107742157 107750184

SANH:

107670392 107672722 107673376 107687999

SGH:	107566860 107592413 107595035 107597930

CCAR:

109059961 109064312(tbx3) 109080111

CAUA:

113048742 113049425 113084526 113091399

CGIB:

127958307 127992970

PTET:

122342995(tbx3a)

LROH:

127165998(tbx3a)

OMC:	131540443(tbx3a)

PPRM:

120469472(tbx3b) 120472383(tbx3a)

RKG:	130078103(tbx3a)

MAMB:

125266501(tbx3b) 125267844(tbx3a)

CIDE:

127513461

CERY:

137033805(tbx3a)

MASI:

127422713 127435633

TROS:

130567752(tbx3a)

TDW:	130419999(tbx3a)

MANU:

129440752(tbx3a)

IPU:	108255409(tbx3b) 108260432(tbx3a)

IFU:	128599223(tbx3b) 128603824(tbx3a)

PHYP:

113531608(tbx3) 113542488

SMEO:

124379395(tbx3a) 124380330(tbx3b)

TFD:	113639759 113641772(tbx3a)

TVC:	132841035(tbx3a)

TRN:	134303312(tbx3a)

AMEX:

103021647(tbx3a) 103043344(tbx3b)

CMAO:

118814538(tbx3a)

EEE:	113583935(tbx3) 113588122

CHAR:

105888899(tbx3a) 105889871(tbx3b)

SPIL:

134089697(tbx3b) 134101332(tbx3a)

TRU:	101069968(tbx3) 101079097

TFS:	130517383(tbx3a) 130526203

TNG:	GSTEN00017195G001 GSTEN00034873G001

LCO:	104924901(tbx3)

NCC:	104956397(tbx3) 104966371

TBEN:

117476794(tbx3a)

CGOB:

115017124(tbx3)

PGEO:

117455766(tbx3a)

GACU:

117535037 117539198(tbx3a)

EMAC:

134868289(tbx3a) 134873273

ELY:	117270102(tbx3a)

EFO:	125906012(tbx3a)

PLEP:

121960284(tbx3a)

SLUC:

116035095(tbx3a)

ECRA:

117959458(tbx3a)

ESP:	116689847 116704292(tbx3)

PFLV:

114570935(tbx3)

GAT:	120832098(tbx3a)

PPUG:

119226964(tbx3a)

AFB:	129101878 129102559(tbx3a)

CLUM:

117740494(tbx3a)

PSWI:

130205026(tbx3a)

CANA:

137783806(tbx3a) 137805157(tbx3b)

CVE:	137867174 137869089(tbx3a)

MSAM:

119891150(tbx3b) 119914804(tbx3a)

SCHU:

122865470(tbx3a) 122876740

CUD:	121524635(tbx3a)

SPUL:

138601991(tbx3a)

LMIX:

132973801 132991980(tbx3a)

ALAT:

119019910 119030618(tbx3a)

ASTR:

137608750(tbx3a)

MZE:	101466675 101473636(tbx3)

ONL:	100694461 100698260(tbx3)

OAU:	116316346 116334214(tbx3a)

OLA:	100049473(tbx3)

OML:	112136126(tbx3a)

CSAI:

133451236 133455187(tbx3a)

XMA:	102221328 102231429(tbx3)

XCO:	114150033(tbx3) 114155012

XHE:	116724789(tbx3) 116730163

PRET:

103460837 103469565 103473795(tbx3)

PFOR:

103149623(tbx3)

PLAI:

106944534(tbx3)

PMEI:

106924242(tbx3)

GAF:	122819481(tbx3a) 122827752

PPRL:

129351617 129366412(tbx3a)

CVG:	107088453(tbx3) 107102669

CTUL:

119777292 119781527(tbx3a)

GMU:	124872499(tbx3a) 124878335

NFU:	107374120(tbx3)

KMR:	108231069(tbx3a)

ALIM:

106514418 106529576 106534649(tbx3)

NWH:	119424951(tbx3a)

AOCE:

111565999 111570614 111574171 111578180(tbx3)

EJA:	138208266(tbx3b) 138211974(tbx3a)

BFRE:

138622587 138629832(tbx3a)

MCEP:

124997141(tbx3a)

CSEM:

103390180(tbx3)

POV:	109626416(tbx3) 109633663

SSEN:

122758592(tbx3a) 122769953

HHIP:

117767839 117771986(tbx3a)

HSP:	118098191(tbx3a) 118114483

PPLT:

128424879(tbx3a) 128439007

SMAU:

118285327(tbx3a) 118314138

LCF:	108878020 108888972(tbx3a)

SDU:	111227464 111237784(tbx3)

SLAL:

111647972 111664883(tbx3)

XGL:	120805022(tbx3b) 120806880(tbx3a)

HCQ:	109514708(tbx3)

SSCV:

125965760 125979910(tbx3a)

SBIA:

133515308(tbx3a)

PEE:	133414038(tbx3a)

PTAO:

133490340(tbx3a)

BPEC:

110160512(tbx3) 110165840

MALB:

109959730 109960673(tbx3)

BSPL:

114846479(tbx3b) 114867050(tbx3a)

SJO:	128380513(tbx3a)

SSCO:

133995040(tbx3a)

SASA:

106563287 106566936 106580546 106584937

STRU:

115159568 115164261 115199654 115204066

OTW:	112236832 112247124 112249702(tbx3b)

OMY:	110509791 110523583 110525900(tbx3b)

OGO:	124007112 124034931 124048967

ONE:	115101165 115111806 115122629 115140693

OKI:	109868717 109874088 109894933

OKE:	118357879 118373207 118385303 118394254(tbx3b)

SALP:

111957561 111961614 111964013 111973826

SNH:	120021491 120026127 120062915

CCLU:

121541664 121582514 121584214(tbx3b)

ELS:	105014509 105015020(tbx3)

SFM:	108927186 108927525(tbx3)

PKI:	111847467(tbx3)

AANG:

118212106(tbx3a) 118237090

CCOG:

133105683 133140847

LOC:	102682460(tbx3)

PSPA:

121297364 121299803

ARUT:

117427874(tbx3a)

PSEX:

120541049(tbx3a)

LCM:	102364919(TBX3)

CMK:	103172753(tbx3a)

RTP:	109927924(tbx3a)

CPLA:

122562727(tbx3a)

HOC:	132827160(tbx3a)

LERI:

129709318(tbx3a)

LRJ:

133348960

CIN:	100185942 445621(tbx2/3)

SPU:	575938(Tbx2/3) 592389

APLC:

ARUN:

PJA:

PCHN:

CQD:

DSV:

RSAN:

RMP:

ABRU:

LPOL:

PMEO:

PVUL:

PCAN:

112561151 112561153 112562743

HRF:	124135001 124135003

HRJ:

HASI:

CANU:

OED:

MCAF:

MMER:

LJP:

LAK:

SMM:	Smp_145230

LLON:

NVE:

EPA:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

TAD:	TRIADDRAFT_59753

» show all

Reference

PMID:22002537

Authors

Martin N, Benhamed M, Nacerddine K, Demarque MD, van Lohuizen M, Dejean A, Bischof O

Title

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.

Journal

EMBO J 31:95-109 (2012)
DOI:10.1038/emboj.2011.370

Sequence

[hsa:6926]

LinkDB

DBGET integrated database retrieval system