| Entry |
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| Name |
glucose-6-phosphate dehydrogenase (NAD+);
Glc6PDH;
azf (gene name);
archaeal zwischenferment
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
D-glucose-6-phosphate:NAD+ 1-oxidoreductase
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| Reaction(IUBMB) |
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+ [RN: R10520]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme catalyses a step of the pentose phosphate pathway. The enzyme from the archaeon Haloferax volcanii is specific for NAD+. cf. EC 1.1.1.363, glucose-6-phosphate dehydrogenase [NAD(P)+] and EC 1.1.1.49, glucose-6-phosphate dehydrogenase (NADP+).
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| History |
EC 1.1.1.388 created 2015
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| Pathway |
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| Orthology |
| K19243 | NAD+ dependent glucose-6-phosphate dehydrogenase |
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| Genes |
» show all
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| Reference |
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| Authors |
Pickl A, Schonheit P |
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| Title |
The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase--The archaeal Zwischenferment. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.388 |
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| LinkDB |
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