KEGG ENZYME: 1.5.1.8

ENZYME: 1.5.1.8

Entry

EC 1.5.1.8                  Enzyme

Name

saccharopine dehydrogenase (NADP+, L-lysine-forming);
lysine-2-oxoglutarate reductase;
lysine-ketoglutarate reductase;
L-lysine-alpha-ketoglutarate reductase;
lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming);
saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase;
6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)

Class

Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)

Reaction(IUBMB)

N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-lysine + 2-oxoglutarate + NADPH + H+ [RN:R00716]

Reaction(KEGG)

R00716

Substrate

N6-(L-1,3-dicarboxypropyl)-L-lysine [CPD:C00449];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

Product

L-lysine [CPD:C00047];
2-oxoglutarate [CPD:C00026];
NADPH [CPD:C00005];
H+ [CPD:C00080]

History

EC 1.5.1.8 created 1972

Pathway

ec00310

Lysine degradation

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K14157

alpha-aminoadipic semialdehyde synthase

Genes

HSA:	10157(AASS)

PTR:	472493(AASS)

PPS:	100983928(AASS)

GGO:	101143865(AASS)

PON:	100454072(AASS)

PPYG:

129040607(AASS)

NLE:	100607105(AASS)

HMH:	116814294(AASS)

SSYN:

129484945(AASS)

MCC:	694594(AASS)

MCF:	102145151(AASS)

MTHB:

126951178

MNI:	105475252(AASS)

CSAB:

103226802(AASS)

CATY:

105598498(AASS)

PANU:

101023478(AASS)

TGE:	112621792(AASS)

MLEU:

105550927(AASS)

RRO:	104657067(AASS)

RBB:	108518504(AASS)

TFN:	117072333(AASS)

PTEH:

111550222 113219515

CANG:

105508558(AASS)

CJC:	100385723(AASS)

SBQ:	101030460(AASS)

CIMI:

108292795(AASS) 108297229

ANAN:

105732088(AASS)

CSYR:

103266259(AASS)

MMUR:

105864150(AASS)

LCAT:

123647228(AASS)

PCOQ:

105817157(AASS)

OGA:	100943543(AASS)

MMU:	30956(Aass)

MCAL:

110296036(Aass)

MPAH:

110316418(Aass)

RNO:	296925(Aass)

MCOC:

116098018(Aass)

ANU:	117721064(Aass)

ASYL:

127678387(Aass)

MUN:	110560725(Aass)

CGE:	100751161(Aass)

MAUA:

101831679(Aass)

PROB:

127215354(Aass)

PLEU:

114695606(Aass)

MORG:

121463453(Aass)

MFOT:

126503976

AAMP:

119806653(Aass)

NGI:	103730601(Aass)

HGL:	101707268(Aass)

CPOC:

100722098(Aass)

CCAN:

109685533(Aass)

DORD:

105988398(Aass)

DSP:	122121749(Aass)

PLOP:

125347072(Aass)

NCAR:

124990904

MMMA:

107144499(Aass)

ITI:	101973939(Aass)

OCU:

100352070

OPI:	101536276(AASS)

TUP:	102489208(AASS)

GVR:	103596796(AASS)

CFA:	482429(AASS)

CLUD:

112678088(AASS)

VVP:	112910607(AASS)

VLG:	121474769(AASS)

NPO:	129502917(AASS)

AML:	100468913(AASS)

UMR:	103676605(AASS)

UAH:	113263479(AASS)

UAR:	123789016(AASS)

ELK:

111152037

LLV:

125080848

MPUF:

101682519

MNP:	132015755(AASS)

MLK:	131829682(AASS)

NVS:	122905024(AASS)

ORO:	101383022(AASS)

EJU:	114210641(AASS)

ZCA:	113911600(AASS)

MLX:	118021028(AASS)

NSU:	110588919(AASS)

LWW:	102739643(AASS)

FCA:	101091272(AASS)

PYU:	121028418(AASS)

PCOO:

112866648(AASS)

PBG:	122488152(AASS)

PVIV:

125160638(AASS)

LRUF:

124523798

LGF:	123606776(AASS)

AJU:

106970654

PTG:	102960744(AASS)

PPAD:

109268907(AASS)

PUC:

125930096

PLEZ:

122210484(AASS)

HHV:	120236729(AASS)

BTA:	520865(AASS)

BOM:	102275417(AASS)

BIU:	109557575(AASS)

BBUB:

102394960(AASS)

BBIS:

104987236(AASS)

CHX:	102185894(AASS)

OAS:	101103973(AASS)

BTAX:

128046624(AASS)

CSUM:

138079866(AASS)

ODA:	120877291(AASS)

CCAD:

122438583(AASS)

MREE:

136170493(AASS)

OVR:	110136706(AASS)

MBEZ:

129552599(AASS)

SSC:	100513962(AASS)

CFR:	102520837(AASS)

CBAI:

105063132(AASS)

CDK:	105085335(AASS)

VPC:	102530174(AASS)

BACU:

103016134(AASS)

BMUS:

118900596(AASS)

LVE:	103085872(AASS)

OOR:	101285244(AASS)

LALB:

132521265 132524607(AASS)

DLE:	111179042(AASS)

PCAD:

102992598(AASS)

PSIU:

116759791(AASS)

NASI:

112408261(AASS)

ECB:	100056260(AASS)

EPZ:	103547307(AASS)

EAI:	106829857(AASS)

MYB:	102254732(AASS)

MYD:	102770634(AASS)

MMYO:

118666463(AASS)

MLF:	102432631(AASS)

MDT:	132242696(AASS)

MYUM:

139016160(AASS)

PKL:	118712123(AASS)

EFUS:

103300691(AASS)

MNA:	107537367(AASS)

DRO:	112299931(AASS)

SHON:

118994001(AASS)

AJM:	119046514(AASS)

PDIC:

114507757(AASS)

PHAS:

123824426(AASS)

MMF:	118619894(AASS)

PPAM:

129062876

HAI:	109371287(AASS)

RFQ:	117018160(AASS)

PALE:

102881018(AASS)

PGIG:

120601214(AASS)

PVP:	105290157(AASS)

RAY:	107500210(AASS)

MJV:	108404217(AASS)

TOD:	119246109(AASS)

SARA:

101548455(AASS)

SFUM:

130027380(AASS)

SETR:

126005783(AASS)

LAV:	100665204(AASS)

TMU:

101358790

ETF:	101659941(AASS)

DNM:	101414881(AASS)

MDO:	100016400(AASS)

GAS:	123250759(AASS)

SHR:	100923009(AASS)

AFZ:

127563973

PCW:	110194178(AASS)

TVP:	118850600(AASS)

PBRV:

138160541(AASS)

OAA:	100076030(AASS)

TACU:

119933086(AASS)

GGA:	417757(AASS)

PCOC:

116243788(AASS)

MGP:	100543809(AASS)

CJO:	107308784(AASS)

TPAI:

128073735(AASS)

LMUT:

125688366(AASS)

NMEL:

110392561(AASS)

APLA:

101793380(AASS)

ACYG:

106044525(AASS)

CATA:

118254260(AASS)

AFUL:

116491208(AASS)

TGU:	100222251(AASS)

LSR:	110483501(AASS)

SCAN:

103813475(AASS)

PMOA:

120510701(AASS)

OTC:	121336320(AASS)

PRUF:

121355789(AASS)

ATRC:

139588412(AASS)

GFR:	102036981(AASS)

FAB:	101818954(AASS)

OMA:	130266122(AASS)

PHI:	102112915(AASS)

PMAJ:

107204864(AASS)

CCAE:

111922957(AASS)

CCW:	104686812(AASS)

CBRC:

103622077(AASS)

ACOE:

138099305(AASS)

ETL:	114064186(AASS)

ZAB:	102066527(AASS)

ZLE:	135442660(AASS)

ACHL:

103803905(AASS)

SVG:	106854054(AASS)

MMEA:

130580767(AASS)

HRT:	120751602(AASS)

SATI:

136360969(AASS)

CCIC:

134043049(AASS)

FPG:	101923487(AASS)

FCH:	102047696(AASS)

CCRI:

104162754(AASS)

NNT:	104409609(AASS)

SHAB:

115605565(AASS)

ACUN:

113490507(AASS)

TALA:

104369177(AASS)

ACHC:

115341719(AASS)

HALD:

104319552(AASS)

HLE:	104840397(AASS)

AGEN:

126044299

HHAR:

128143353(AASS)

GCL:

127014004

LDI:	104342779(AASS)

MNB:

103776647

DPUB:

104303122(AASS)

PPUS:

135174657(AASS)

AVIT:

104274653(AASS)

BRHI:

104496765(AASS)

EGZ:	104125682(AASS)

NNI:	104011825(AASS)

PCRI:

104029622(AASS)

PCAO:

104042521(AASS)

PADL:

103923842(AASS)

AFOR:

103905212(AASS)

FGA:	104080942(AASS)

GSTE:

104250234(AASS)

CBOY:

140651547(AASS)

CLV:	102094241(AASS)

MUI:	104537916(AASS)

PGUU:

104457428(AASS)

PLET:

104613552(AASS)

EHS:	104513185(AASS)

CMAC:

104473130(AASS)

TEO:	104378926(AASS)

BREG:

104636344(AASS)

OHA:	104330036(AASS)

ACAR:

104529636(AASS)

CPEA:

104394675(AASS)

CVF:	104285242(AASS)

RTD:	128900827(AASS)

CRID:

134510232(AASS)

AAM:	106495938(AASS)

AROW:

112966683(AASS)

NPD:	112957907(AASS)

TGT:	104578451(AASS)

DNE:	112990916(AASS)

SCAM:

104152135(AASS)

ASN:	102376316(AASS)

AMJ:	102574453(AASS)

CPOO:

109315640(AASS)

GGN:	109292023(AASS)

PSS:	102454542(AASS)

CMY:	102948389(AASS)

CCAY:

125630370(AASS)

DCC:	119842928(AASS)

CPIC:

101934272(AASS)

TST:	117876370(AASS)

CABI:

116831587(AASS)

MRV:	120388288(AASS)

ACS:	100553247(aass)

ASAO:

132776275(AASS)

PVT:	110084070(AASS)

SUND:

121930747(AASS)

PBI:	103054458(AASS)

PMUR:

107293701(AASS)

CTIG:

120301264(AASS)

TSR:	106555089(AASS)

PGUT:

117673614(AASS)

APRI:

131202393(AASS)

PTEX:

113445073(AASS)

NSS:	113413051(AASS)

VKO:	123019869(AASS)

PMUA:

114605071(AASS)

PRAF:

128422072(AASS)

ZVI:	118090844(AASS)

HCG:	128327296(AASS)

GJA:	107111118(AASS)

STOW:

125435842(AASS)

EMC:	129335988(AASS)

XLA:	444409(aass.L)

XTR:	496923(aass)

NPR:	108788040(AASS)

RTEM:

120931849(AASS)

BBUF:

120981869(AASS)

BGAR:

122927937(AASS)

PWL:	138288354(AASS)

MUO:	115478577(AASS)

GSH:	117367147(AASS)

DRE:	556229(aass)

SRX:	107752301 107753626

SANH:

107678990 107698474

SGH:

107575779

CCAR:

109050748 109061151(aass)

CAUA:

113066967(aass)

CGIB:

127947095 127953010

PTET:

122330775(aass)

LROH:

127157008(aass)

OMC:	131534050(aass)

PPRM:

120469052(aass)

MAMB:

125247135(aass)

CIDE:

127507189

CERY:

137015258(aass)

MASI:

127435942

TROS:

130551474(aass)

TDW:	130413823(aass)

MANU:

129433156(aass)

PDAB:

135781504(aass)

IPU:

108274751

IFU:	128618341(aass)

PHYP:

113529768(aass)

SMEO:

124392555(aass)

TFD:	113660164(aass)

TVC:	132856901(aass)

CGAR:

128507821(aass)

NGRA:

132881828(aass)

TRN:	134310725(aass)

AMEX:

103040216(aass)

CMAO:

118811735(aass)

EEE:	113582558(aass)

CHAR:

105901951(aass)

SPIL:

134094715(aass)

TRU:	101061348(aass)

TFS:	130536227(aass)

TNG:	GSTEN00019707G001

LCO:	104927983(aass)

TBEN:

117471823(aass)

CGOB:

115009199(aass)

PGEO:

117448336(aass)

GACU:

117536875(aass)

EMAC:

134880987(aass)

ELY:	117261991(aass)

EFO:	125887417(aass)

SLUC:

116036255(aass)

ECRA:

117949029(aass)

ESP:	116693715(aass)

PFLV:

114559584(aass)

GAT:	120808988(aass)

PPUG:

119195464(aass)

AFB:	129108028(aass)

CLUM:

117732281(aass)

PSWI:

130195102(aass)

CANA:

137803994(aass)

CVE:	137881303(aass)

MSAM:

119893411(aass)

SCHU:

122874397(aass)

CUD:	121515421(aass)

SPUL:

138613278(aass)

LMIX:

132973540(aass)

ALAT:

119023863(aass)

ASTR:

137593959(aass)

MZE:	101483693(aass)

ONL:	100700037(aass)

OAU:	116322054(aass)

OLA:	101155996(aass)

OML:	112139570(aass)

CSAI:

133444430(aass)

XMA:	102235893(aass)

XCO:	114136268(aass)

XHE:	116708415(aass)

PRET:

103465787(aass)

PFOR:

103130309(aass)

PLAI:

106934445(aass)

PMEI:

106934269(aass)

GAF:	122836023(aass)

PPRL:

129355816(aass)

CVG:	107092787(aass)

CTUL:

119793851(aass)

GMU:	124882332(aass)

NFU:	107389491(aass)

KMR:	108247341(aass)

ALIM:

106530280(aass)

NWH:	119416419(aass)

AOCE:

111567529(aass)

EJA:	138206163(aass)

BFRE:

138632868(aass)

MCEP:

125015290(aasS)

CSEM:

103379906(aass)

POV:	109624603(aass)

SSEN:

122775709(aass)

SSOE:

131470054(aass)

HHIP:

117762862(aass)

HSP:	118109577(aass)

PPLT:

128444540(aass)

SMAU:

118315049(aass)

LCF:

108902912

SDU:	111235992(aass)

SLAL:

111665076(aass)

XGL:	120793423(aass)

HCQ:	109522992(aass)

SSCV:

125970260(aass)

SBIA:

133512160(aass)

PEE:	133402816(aass)

PTAO:

133477961(aass)

BPEC:

110166755(aass)

ENY:	140348819(aass)

MALB:

109956395(aass)

BSPL:

114857226(aass)

SJO:	128358975(aass)

SSCO:

133981684(aass)

GMH:	115550831(aass)

SASA:

106584550

STRU:

115192728

OTW:	112220815(aass)

OMY:	100136272(aass)

OGO:	124037596(aass)

ONE:

115144791

OKI:

109897782

OKE:	118359306(aass)

OMM:

135556611

OCLA:

139406456

SALP:

111971984

SNH:	120052382(aass)

CCLU:

121531191 121540551(aass)

ELS:	105018620(aass)

OEP:	134021266(aass)

SFM:	108931602(aass)

PKI:	111851693(aass)

AANG:

118231204(aass)

AROT:

135258981(aass)

CCOG:

133135312 133135425(aass)

LOC:	102692209(aass)

PSPA:

121319777(aass)

ARUT:

117415599(aass)

PSEX:

120533967(aass)

LCM:	102353181(AASS)

CMK:	103179368(aass)

RTP:	109937592(aass)

CPLA:

122559543(aass)

HOC:	132824761(aass)

LERI:

129706180(aass)

PMRN:

116942293(AASS) 116942294

LRJ:	133349553(AASS)

BFO:	118415155 118415358 118415478 118427549

BBEL:

109477241 109477755

CIN:

104265748

SCLV:

120340173

SPU:

592682

AJJ:

139961000

APLC:

110989169

ARUN:

117305920

AAMU:

139953740

AFIL:

140148928 140149217 140159252 140159316

AJC:

117108583

SKO:	100367386 102804295

PFLL:

139134387 139135166

DME:	Dmel_CG7144(LKRSDH)

DER:

6542219

DSE:

6611574

DSI:	Dsimw501_GD22468(Dsim_GD22468)

DYA:	Dyak_GE18334

DAN:

6505494

DSR:

110177043

DPO:

4817347

DPE:	113565906 6589787

DMN:

108163154

DWI:

6642305

DGR:

6562901

DMO:	Dmoj_GI18086

DAZ:

108609826

DNV:

115562596

DHE:

111592904

DVI:	6628879(LKRSDH)

CCAT:

101450855

BOD:

106621807

BDR:

105229197

RZE:

108358102

AOQ:

129248452

ALUD:

128863654

TDA:

119689879

MDE:

101897193

SCAC:

106092052

LCQ:

111679431

LSQ:

119613732

CVJ:	135950063(LKRSDH)

GFS:

119633785

ECOE:

129951393

CLON:

129608299

HIS:

119661555

AGA:

1275481

ACOZ:

120957044

AARA:

120905075

AMER:

121596677

ASTE:

118512449

AMAP:

126564046

AFUN:

125762287

AMOU:

128302314

AMRS:

128710837

AALI:

118459293

ACOS:

131262813

AAG:

5565118

AALB:

109407239 109414306

ASUA:

134212693

CQU:	CpipJ_CPIJ000416

CPII:

120420617

CBRI:

134829268

CNS:

116346778

BCOO:

119072875

LLL:

129791156

PPAP:

129807038

AME:

552130

ACER:

107993221

ALAB:

122719092

ADR:

102673302

AFLR:

100863927

BIM:

100740455

BBIF:

117214583

BVK:

117242720

BVAN:

117156401

BHUN:

126866851

BTER:

100649340

BAFF:

126928864

BPYO:

122572167

BPAS:

132908982

FVI:

122527656

CCAL:

108624730

OBB:

114872249

OLG:

117606544

MGEN:

117225381

NMEA:

116432045

SOC:

105196134

MPHA:

105839608

AEC:

105151834

ACEP:

105617717

PBAR:

105430393

VEM:

105559362

COBS:

139107656(Lkrsdh)

TLN:	139811247(Lkrsdh)

HST:

105187630

DQU:

106742161

CFO:

105250242

FEX:

115245296

PMEC:

138936380(Lkrsdh)

LHU:	105677283(LKRSDH)

PGC:

109862633

OBO:

105279439

PCF:

106791120

PFUC:

122518837

VPS:

122637751

VCRB:

124432726

VVE:

124958004

NVI:

100123521

CSOL:

105362224

TPRE:

106657970 111694081

LHT:

122509485

LBD:

127278803

MDL:

103579460

CGLO:

123274549

FAS:

105273192

DAM:

107035469

AGIF:

122850241

CINS:

118066811

VCAN:

122408775

CCIN:

107270374

DSM:

124405981

NPT:	124211155(LKRSDH)

NFB:

124175823

NLO:

107227399

NVG:

124298021

AROA:

105689746

TCA:

660388

TMOL:

138127038(LKRSDH)

DPA:	109539617 109539618

ESIM:

136418765(LKRSDH)

EFOR:

136348019(LKRSDH)

SOY:

115886547

AGRG:

126748485

ATD:

109604531

CSET:

123312888

HAXR:

123680772

AGB:	108913067 108916332

LDC:

111517256

DVV:

126880063

NVL:	108562347 108569430

APLN:

108744951

PPYR:

116175770 116182203

OTU:

111421131

BMOR:

101743783

BMAN:

114246112

MSEX:

115445397

DPL:	KGM_208487

BANY:

112043908

MJU:

123869631

NIQ:

126771513

VCD:

124532101

MCIX:

123656034

PMAC:

106714130

PPOT:

106106693

PXU:

106127440

BPHI:

137932643(LKRSDH)

PRAP:

111001125

PBX:

123720716

PNAP:

125052192

ZCE:

119834310

CCRC:

123693868

LSIN:

126971766

AAGE:

121739622

HAW:	110384393(Lkrsdh)

HZE:

124629954

TNL:	113497359 113503145

SLIU:

111348498

OFU:

114354176

ONU:

135072485

ATRA:

106129177

GMW:

113512405

PXY:

105384700

PGW:

126367999

LGLY:

125230114

CSTB:

134744773

CFEL:

113366242

CCRN:

123305173

API:	100163885 100166221

DNX:

107166523

AGS:

114121214

RMD:

113557325

ACOO:

126833642

DVT:

126895879

BTAB:

109042690

DCI:

103507716

CLEC:

106664604

HHAL:

106686293(LKRSDH)

NLU:

111052657

HVI:

124359779

MQU:	128995051 129005465

PHU:	Phum_PHUM016080

FOC:

113206348

TPAL:

117640314

ZNE:

110831369

CSEC:

111874328

PAME:

138707633(LKRSDH)

SGRE:

126298160

BROR:

134535490

IEL:

124166535

HAMR:

139695428(LKRSDH)

FCD:	110853651 110858421

DPX:	DAPPUDRAFT_334150

DMK:	116929230 123475612

DPZ:

124352613

AFRA:

136042118

PVM:	113818204(LKRSDH)

PJA:

122258971

PCHN:

125042398

PMOO:

119590073

HAME:

121854523

PCLA:

123764920(LKRSDH)

PTRU:

123505951 123506511

ESN:

126991216

MNZ:

135216389

MRJ:	136849009(LKRSDH)

PORN:

139765599(LKRSDH)

HAZT:

108675946

EAF:

111698421

LSM:	121115761(LKRSDH)

TCF:

131891242

PPOI:

119090302

ISC:

8031023

DSV:

119465726

RSAN:

119406956

RMP:

119163450

VDE:

111248839

VJA:

111260394

TUT:

107367889

DPTE:

113793337

DFR:

124492124

CSCU:

111632261

CVS:	136974894(LKRSDH)

PTEP:

107451145

ABRU:

129981903

UDV:

129222849

SDM:

118186528

PMEO:

129588049

CEL:	CELE_R02D3.1(aass-1)

CBR:

CBG_13546

CRQ:	GCK72_016303

NAI:	NECAME_02067

HRO:	HELRODRAFT_110863

LGI:	LOTGIDRAFT_218445

PVUL:

126828352

PCAN:

112571884

LSAX:

138964590 138964916

BGT:

106072931

GAE:

121368084

HRF:

124145923

HRJ:

124252979

HASI:

137295597

HCRA:

139445553

CRG:

105322594

CANU:

128158488

CVN:

111106992

OED:

130048327

MYI:

110443085

PMAX:

117331930

AIRR:

138336990

MCAF:

127705507

MMER:

123529809

RPHI:

132730326 132736418

DPOL:

127858137 127867537

MAEA:

128216761

OBI:

106869155

OSN:

115219785

LJP:

135471837

LAK:	106164010 106175203 106177321

OVI:	T265_08833

LLON:

135491492

NVE:

5509803

EPA:

110241709

ATEN:

116286530

ADF:

107348484

AMIL:

114959146

MCAZ:

138056879

MFOO:

138010574

PDAM:

113684100

SPIS:

111338891

DGT:

114521682

XEN:

124434613

HMG:

100199926

HSY:

130625325

RES:	135692723 135692727

TAD:	TRIADDRAFT_36926

AQU:

100641330

ATH:

AT4G33150

ALY:	9303270 9305293

CRB:	111829356 17877973

CSAT:

104716844 104721500 104729943 104733158

EUS:	EUTSA_v10024287mg

BRP:	103849713 103862218

BNA:	106368756 106408600 106423277 106438508

BOE:	106305178 106310570

RSZ:	108843027 108852642 130508219

THJ:

104804447

CPAP:

110812057

CIT:

102608315

CIC:	CICLE_v10007313mg

PVY:	116114036 116118520

MINC:

123194548

TCC:

18588195

GRA:

105772791

GHI:	107900997 107962841

GAB:

108486121

DZI:	111285465 111285563 111303021

EGR:

104437949

RARG:

115746750

GMX:	100811246 100813294

GSJ:	114381717 114393744

PVU:

137807124

VRA:

106769194

VAR:

108320668

VUN:

114178190

VUM:

124838538

CCAJ:

109807314

APRC:

113847964

MTR:

11443731

TPRA:

123907166

CAM:

101500267

PSAT:

127138739

VVO:

131630128

LJA:

130709866

ADU:

107495845

AIP:

107638430

AHF:	112696156 112740737

LANG:

109356534

PCIN:

129308194

QSA:	O6P43_003776

FVE:

101310736

AANS:

126796586

RCN:

112185872

PPER:

18769367

PMUM:

103340501

PAVI:

110748930

PDUL:

117635831

MDM:

103454158

MSYL:

126608195

PXB:

103959117

PCOX:

137746970

ZJU:

107423840

MNT:

21402511

CSAV:

115705496

CSV:

101214976

CMO:

103492407

BHJ:

120071235

MCHA:

111016508

CMAX:

111466259 111484863

CMOS:

111441122 111461645

CPEP:

111780162 111793871

RCU:

8259021

MEAN:

126668988

JCU:

105638037

HBR:	110636542 110636543

MESC:

110603783

POP:

18100258

PEU:

105111406

PALZ:

118048527

PNZ:	133689921 133690143

JRE:

108993578

CILL:

122304213

CAVE:

132165282

AGLU:

133857423

QSU:

111987337

QLO:

115969174

TWL:	120005172 120005358

VVI:

100268037

VRI:

117925033

SLY:

101261722

SPEN:

107026571

SOT:

102586908

SSTN:

125877804

SDUL:

129891201

CANN:

107877934

LBB:

132603356

NTA:	107798112 107827281

NSY:

104234932

NTO:

104110270

NAU:

109206597

INI:

109190601

ITR:

116022700

SIND:

105173734

OEU:

111403740

EGT:

105970939

SSPL:

121796221 121799967

SHIS:

125197015

APAN:

127264780

HAN:

110928432

ECAD:

122599311

LSV:

111910406

DCR:

108192546

CSIN:

114261914

RVL:

131327279

AEW:	130756747 130789657

DLT:

127805779

BVG:	104901700 104901702

SOE:

110799548

CQI:	110715969 110721851

ATRI:

130816174

MOF:

131157283

MING:

122066726

TSS:

122669199

PSOM:

113326588 113339287 113339302

OSA:

4330940

DOSA:

Os02g0783700

OBR:

102714890

OGL:

127762320

BDI:

100824912

ATS:

109771574

TDC:	119318189 119323058

TAES:

123128669 123138725 123145804

TUA:

125514986

LPER:

127305673

LRD:	124693311 124693332

SBI:

8081954

ZMA:

541648

MFLO:

136478215 136478247

SITA:

101756273

SVS:

117840635

PVIR:

120644250 120657403

PHAI:

112891708

PAUA:

133919944 133921062

PDA:

103716942

EGU:

105041974

MUS:

103969029

ZOF:	122000812 122005102

DCT:

110110517

PEQ:

110033140

AOF:

109844832

MSIN:

131251814

ACAK:

137956690

NCOL:

116257349

ATR:

18423952

CJF:

131050789

SMO:	SELMODRAFT_103525 SELMODRAFT_173433

PPP:

112278437

GSL:	Gasu_48290

CNE:

CNA02370

CNB:

CNBA2210

CNG:	CNAG_00247

CGI:	CGB_B3130C

CDEU:

CNBG_0322

CDEC:

89990217(IAS62_003445)

CTEG:

91989555(I308_102699)

CDEP:

91087707(L203_103496)

KMG:	30160678(I203_104189)

KNE:	92178845(IAR55_001586)

KDJ:	28968319(I303_104401)

KBI:	30209394(I302_105871)

KPIN:

30172581(I206_104213)

KSH:	87955391(IL334_003260)

TMS:	TREMEDRAFT_29255

TASA:

A1Q1_07452

CCAC:

CcaHIS019_0601920(CcaverHIS019_0601920)

TVS:	TRAVEDRAFT_67257

DSQ:	DICSQDRAFT_92955

PCO:	PHACADRAFT_177943

SHS:	STEHIDRAFT_102335

HIR:	HETIRDRAFT_235542

PSQ:	PUNSTDRAFT_76716

ADL:	AURDEDRAFT_83944

FME:	FOMMEDRAFT_126943

GTR:	GLOTRDRAFT_140080

RSX:	RhiXN_07831

LBC:	LACBIDRAFT_241294

CCI:	CC1G_15806

ABP:	AGABI1DRAFT77562(AGABI1DRAFT_77562)

ABV:	AGABI2DRAFT188762(AGABI2DRAFT_188762)

MRR:	Moror_7544

E1B28_003344

SCM:	SCHCO_02629850(SCHCODRAFT_02629850)

CPUT:

CONPUDRAFT_128756 CONPUDRAFT_147051

SLA:	SERLADRAFT_350049

PTRC:

PtA15_11A440

PSTR:

Pst134EA_017495

MLR:	MELLADRAFT_90413

RIE:	OCT59_008979

MBR:	MONBRDRAFT_16322

SRE:	PTSG_00811

DDI:	DDB_G0284835(aass)

DPP:	DICPUDRAFT_51448

DFA:	DFA_03752(aass)

TET:	TTHERM_00149450

PTM:	GSPATT00020034001 GSPATT00022271001 GSPATT00031371001

PTI:	PHATRDRAFT_54394(LKRSDH)

FCY:	FRACYDRAFT_264866

TPS:	THAPSDRAFT_261124

PIF:	PITG_03530

PSOJ:

PHYSODRAFT_552101

BLAC:

94344421(CCR75_000644)

SPAR:

SPRG_16261

NGR:	NAEGRDRAFT_79185

EHX:	EMIHUDRAFT_467888 EMIHUDRAFT_74668

» show all

Reference

1 [PMID:4385118]

Authors

Hutzler J, Dancis J.

Title

Conversion of lysine to saccharopine by human tissues.

Journal

Biochim Biophys Acta 158:62-9 (1968)
DOI:10.1016/0304-4165(68)90072-X

Reference

2 [PMID:6434529]

Authors

Markovitz PJ, Chuang DT, Cox RP.

Title

Familial hyperlysinemias. Purification and characterization of the bifunctional aminoadipic semialdehyde synthase with lysine-ketoglutarate reductase and saccharopine dehydrogenase activities.

Journal

J Biol Chem 259:11643-6 (1984)

Other DBs

ExplorEnz - The Enzyme Database:

1.5.1.8

IUBMB Enzyme Nomenclature:

1.5.1.8

ExPASy - ENZYME nomenclature database:

1.5.1.8

BRENDA, the Enzyme Database:

1.5.1.8

CAS:

9031-19-0

LinkDB

DBGET integrated database retrieval system